A5081031846- Vasculitis and related conditions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Eating Disorders and Behaviors
- Otitis Media and Relapsing Polychondritis
- Renal Diseases and Glomerulopathies
- Sarcoidosis and Beryllium Toxicity Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Diet and metabolism studies
- Kawasaki Disease and Coronary Complications
- Obesity and Health Practices
- Pathogenesis and Treatment of Hiccups
- Medicinal Plant Extracts Effects
- Retinal and Optic Conditions
- Renal and Vascular Pathologies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Obsessive-Compulsive Spectrum Disorders
- Ocular Diseases and Behçet’s Syndrome
- Biochemical effects in animals
- Complementary and Alternative Medicine Studies
- Sleep and related disorders
- Bariatric Surgery and Outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Gender Roles and Identity Studies
- Complement system in diseases
- Whipple's Disease and Interleukins
Research Network (United States)
2024
Hôpital du Sacré-Cœur de Montréal
2021-2024
Université de Montréal
2021-2024
Mount Sinai Hospital
2023
Health Net
2023
University of Toronto
2020-2022
Mount Sinai Hospital
2020-2022
University Health Network
2021
University of Arizona
2008-2014
Integrative Medicine Institute
2008
Antineutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAV) are small-vessel that include granulomatosis with polyangiitis (formerly Wegener's granulomatosis), microscopic polyangiitis, and eosinophilic (Churg - Strauss syndrome). Renal-limited AAV can be considered a fourth entity. Despite their rarity still unknown cause(s), research into has been very active over the past decades allowed for development of new therapeutic regimens. The pathogenesis is complex process immune...
Objective Optic nerve sheath enhancement on magnetic resonance imaging has been reported in patients with giant cell arteritis (GCA), or without visual manifestations. Whether similar findings can be documented ultrasound is unknown. a point‐of‐care, easy to learn, rapid, and noninvasive technique. This study aims investigate whether optic diameter (ONSD) measured useful the diagnosis of active, new‐onset GCA. Methods A single‐center, diagnostic accuracy was performed from June November 2022...
<h3>Abstract</h3> <h3>Background</h3> Lack of functional evidence hampers variant interpretation, leaving a large proportion cases with suspected Mendelian disorder without genetic diagnosis after genome or whole exome sequencing (WES). Research studies advocate to further sequence transcriptomes directly and systematically probe gene expression defects. However, collection additional biopsies, establishment lab workflows, analytical pipelines, defined concepts in clinical interpretation...
To assess and compare the performance of giant cell arteritis probability score (GCAPS), Ing score, Bhavsar-Khalidi (BK score), color Doppler ultrasound (CDUS) halo count, to predict a final diagnosis (GCA).
OBJECTIVE To evaluate the association between BMI and mortality in women men with type II diabetes. RESEARCH DESIGN AND METHODS Fasting plasma glucose (FPG), height weight measurements, medical history were obtained from 4,483 community-dwelling adults, aged 40–79 years, 1972–1974. A total of 373 persons either a diabetes or FPG ≥ 7.77 mmol/l studied. Subjects grouped into four sex-specific categories based on U.S. population data. Vital status after 14 years was known for 99.9% patients Cox...
Positive antineutrophil cytoplasmic antibodies (ANCAs) may occur in the setting of interstitial lung disease (ILD), with or without ANCA-associated vasculitis (AAV). We aim to compare characteristics and clinical course patients ILD positive ANCA (ANCA-ILD) those negative ANCA.
The aim was to compare the accuracy of colour Doppler ultrasonography (CDUS) and temporal artery biopsy (TAB) establish final diagnosis GCA determine how probability score (GCAPS) performs as a risk stratification tool.Descriptive statistics were performed on retrospective cohort patients referred our vasculitis referral centre between 1 July 2017 October 2020 for suspected GCA. CDUS, TAB, centre-specific TAB (vasculitis vs referring hospitals) GCAPS compared against determined by expert;...
Objective Takayasu arteritis (TA) leads to stenotic disease. Aneurysmal lesions are rarer. This study assessed the main characteristics of aneurysmal disease in a Canadian cohort patients with TA. Methods monocentric retrospective included TA followed at Mount Sinai Hospital Vasculitis Clinic Toronto. Diagnosis was based on clinical findings and/or satisfied 1990 American College Rheumatology classification criteria. Results Seventy-four were included. At any time, found 23 (31%) patients....
Abstract Introduction/Objectives Optic nerve sheath (ONS) enhancement using magnetic resonance imaging of the orbits was observed in patients with giant cell arteritis (GCA). We previously showed that ONS diameter (ONSD) by bedside ultrasound is increased patient active GCA. This study aims to assess whether ONSD decreases clinical remission Methods A prospective cohort conducted from June 2022 January 2023. Patients who had an optic at GCA diagnosis as part a previous crosssectional were...