- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Aortic Disease and Treatment Approaches
- Sarcoma Diagnosis and Treatment
- Hip disorders and treatments
- Musculoskeletal synovial abnormalities and treatments
- Aortic aneurysm repair treatments
- Congenital Heart Disease Studies
- Pelvic and Acetabular Injuries
- Neurogenetic and Muscular Disorders Research
- Metabolism and Genetic Disorders
- Gene Regulatory Network Analysis
- Diverticular Disease and Complications
- Ultrasound in Clinical Applications
- Tracheal and airway disorders
- Semiconductor Lasers and Optical Devices
- Bone Tumor Diagnosis and Treatments
- Surgical Sutures and Adhesives
- Vascular Tumors and Angiosarcomas
- Hip and Femur Fractures
- Intracranial Aneurysms: Treatment and Complications
- Cardiac Imaging and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Laser Material Processing Techniques
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2023
Istituto Ortopedico Rizzoli
2019-2023
The Microsoft Research - University of Trento Centre for Computational and Systems Biology
2023
University of Trento
2023
Università Cattolica del Sacro Cuore
2014
Ospedale San Filippo Neri
2006
University of Florence
1994
Alzheimer's disease is the most common form of dementia. Notwithstanding huge investments in drug development, only one disease-modifying treatment has been recently approved. Here we present a single-cell-led systems biology pipeline for identification repurposing candidates. Using single-cell RNA sequencing data brain tissues from patients with disease, genome-wide association study results, and multiple gene annotation resources, built multi-cellular molecular network that leveraged...
Aim of this study was to describe the clinical outcomes 16 patients with iliopsoas (IP) impingement after primary total hip arthroplasty (THA), treated an arthroscopic tendon release.16 (11 females/5 males), a mean age 57.8 ± 11.1 years (age at THA: 54.4 11 years) and diagnosis IP THA, were Wettstein tenotomy. Preoperatively, every patient underwent diagnostic ultrasonography guided peritendinous injection computed tomography (CT) scan. Every clinically evaluated using WOMAC score....
The aim of this study was to evaluate the middle term cup survival, assess functional implementation and radiographic evolution tantalum acetabular cups implanted on patients with a history pelvic radiotherapy.From 2005 2013, we performed 12 THA replacements (4 males 8 females; mean age: 46.6 years (range 25-75)) irradiated bone Trabecular metal cups, primary implants 4 revision implants. radiation dose delivered 5500 cGy 3000 cGy-13,600 cGy). follow-up 68 months, ranging from 38 136....
The accuracy of scintigraphic evidence perfusion defects, even when classified as 'high probability' by matching with ventilation techniques or thoracic roentenograms is unsatisfactory used without a pre-test clinical evaluation probability. Although unusual, complete near-complete unilateral absence in lung normal controlaterally must alert clinicians to the possibility false-positive result. In such instances, administration therapeutic dosages fibrinolitic and antithrombotic agents (or...
Recurrent dislocations are still the most frequent reason for revision in total hip arthroplasty (THA). The impact of bearing surfaces on is controversial. We hypothesized that: (1) influence revisions due to dislocations; (2) ceramic-on-ceramic reduced adjusted models; (3) Delta-on-Delta bearings comparison with cross-linked polyethylene. regional registry was enquired about and instability. Unadjusted rates were provided, including sex, age (<65 years or ≥65 years), head diameter (≤28 mm...
The aim is to compare the results of isolated hip arthroscopy in patients with borderline dysplasia Lateral center edge angle (LCEA) between 18° and 25° a control group normal LCEA (> 25°).Fifty arthroscopies performed 45 were retrospectively evaluated. Exclusion criteria were: age > 40, arthritis grade 2 according Tonnis classification, femoral head avascular necrosis, pediatric's orthopaedics conditions true < 18°.Two groups identified: A 15 hips Group B made 35 25°.The homogeneous for...
Articular surface replacement (ASR) XL implants exhibit higher-than-expected revision rates, blood ion concentrations and soft tissue lesions, making revisions troublesome potentially unsatisfying. Appropriate techniques outcomes in ASR are rarely documented. The aims of this study were the assessments pre-revision data, post-revision clinical radiographic levels isolated acetabular performed using highly porous titanium cups Delta ceramic articulations.18 16 patients Ti-Por (Adler Ortho,...
Abstract Background Soft-tissue sarcomas (STS) are rare in hand and foot. In this paper we present a case of reconstruction Achilles tendon defect with peroneus brevis transfer reinforced medial gastrocnemius fascia plantaris after excision local recurrence epithelioid sarcoma. Case presentation Fifty-five years-old female. MRI showed lump 5 × 2,5 2 cm into Achille’s invasion the anterior fat tissue but no surrounding bones. The patient underwent tumour tendinous transfer. Surgical technique...
Federica Mariotti, Francesco Castagnini, Massimiliano De Paolis, Maurizio Montalti, Emanuele Diquattro, Monica Cosentino, Barbara Bordini, Traina