A5051770939- Genetic diversity and population structure
- Plant and animal studies
- Lepidoptera: Biology and Taxonomy
- Genomics and Phylogenetic Studies
- Ecology and Vegetation Dynamics Studies
- RNA and protein synthesis mechanisms
- Evolution and Genetic Dynamics
- Insect and Arachnid Ecology and Behavior
- Agriculture and Biological Studies
- Chromosomal and Genetic Variations
- Plant Reproductive Biology
- CRISPR and Genetic Engineering
- Oil Palm Production and Sustainability
- Insect Pheromone Research and Control
- Species Distribution and Climate Change
- Insect Utilization and Effects
- Insect Resistance and Genetics
- Avian ecology and behavior
- DNA Repair Mechanisms
- Invertebrate Taxonomy and Ecology
- Genetic and Environmental Crop Studies
- Plant Virus Research Studies
- Insect-Plant Interactions and Control
- Animal Behavior and Reproduction
Uppsala University
2020-2025
Wellcome Sanger Institute
2024
University of Cambridge
2023
Abstract Karyotypes are generally conserved between closely related species and large chromosome rearrangements typically have negative fitness consequences in heterozygotes, potentially driving speciation. In the order Lepidoptera, most investigated ancestral karyotype gene synteny is often across deep divergence, although examples of extensive genome reshuffling recently been demonstrated. The genus Leptidea has an unusual level variation rearranged sex chromosomes, but extent...
Recombination is a key molecular mechanism that has profound implications on both micro- and macroevolutionary processes. However, the determinants of recombination rate variation in holocentric organisms are poorly understood, particular Lepidoptera (moths butterflies). The wood white butterfly (
Reshuffling of genetic variation occurs both by independent assortment chromosomes and homologous recombination. Such reshuffling can generate novel allele combinations break linkage between advantageous deleterious variants which increases the potential efficacy natural selection. Here we used high-density maps to characterize global regional recombination rate in two populations wood white butterfly (Leptidea sinapis) that differ considerably their karyotype as a consequence at least 27...
Characterization of gene family expansions and crossing over is crucial for understanding how organisms adapt to the environment. Here, we develop a high-density linkage map detailed genome annotation painted lady butterfly (Vanessa cardui) - non-diapausing, highly polyphagous species famous its long-distance migratory behavior almost cosmopolitan distribution. Our results reveal complex interplay between regional recombination rate variation, duplications transposable element activity...
ABSTRACT Chromosomal rearrangements, such as inversions, have received considerable attention in the speciation literature due to their hampering effects on recombination. Less is known about how other chromosome fissions and fusions, can affect evolution of reproductive isolation. Here, we use crosses between populations wood white butterfly ( Leptidea sinapis ) with different karyotypes identify genomic regions associated hybrid inviability. We map inviability candidate loci by contrasting...
Abstract In a time with decreasing biodiversity, especially among insects, detailed understanding about specific resource utilization strategies is crucial. The physiological and behavioural responses to host switches in phytophagous insects are poorly understood. Earlier studies indicate that plant switch might be associated distinctive molecular different lineages. Expanding the assessment of such associations across Lepidoptera will reveal if there general patterns adaptive responses, or...
Migration is a complex behavior involving the synchronisation of many physiological and behavioral processes. Environmental cues must thus be interpreted to make decisions regarding resource allocation between, for example, migration or reproduction. In butterflies, lack host plants sustain new generation may indicate need migrate. Here, we used painted lady butterfly ( Vanessa cardui ) as model characterize gene expression variation in response plant availability. Assessment availability...
<ns3:p>We present a genome assembly from an individual male <ns3:italic>Leptidea sinapis</ns3:italic> (the wood white; Arthropoda; Insecta; Lepidoptera; Pieridae). The sequence is 686 megabases in span. majority (99.99%) of the scaffolded into 48 chromosomal pseudomolecules, with three Z sex chromosomes assembled. Gene annotation this on Ensembl has identified 14,800 protein coding genes.</ns3:p>
The oogenesis-flight syndrome reflects the temporal allocation of energy resources between dispersal / migration and reproduction is a key concept in research on migratory behaviour animals. In butterflies, host plant abundance quality may act as environmental cues to switch two states, but mechanisms regulating this process are virtually unknown. Here, we used an experimental set-up assess how variation affected activity regulatory elements painted lady butterfly ( Vanessa cardui ), model...
Abstract Reshuffling of genetic variation occurs both by independent assortment chromosomes and homologous recombination. Such reshuffling can generate novel allele combinations break linkage between advantageous deleterious variants which increases the potential efficacy natural selection. Here we used high-density maps to characterize global regional recombination rate in two populations wood white butterfly ( Leptidea sinapis ) with distinct karyotypes. The data were compared estimates...
Abstract Coding sequence evolution is influenced by both natural selection and neutral evolutionary forces. In many species, the effects of mutation bias, codon usage, GC-biased gene conversion (gBGC) on have not been detailed. Quantification how these forces shape substitution patterns therefore necessary to understand strength direction selection. Here, we used comparative genomics investigate association between base composition usage bias in butterflies moths (Lepidoptera), including an...
Abstract Genetic recombination is a key molecular mechanism that has profound implications on both micro- and macro-evolutionary processes. However, the determinants of rate variation in holocentric organisms are poorly understood, particular Lepidoptera (moths butterflies). The wood white butterfly ( Leptidea sinapis ) shows considerable intraspecific chromosome numbers suitable system for studying regional its potential underpinnings. Here, we developed large wholegenome resequencing data...
Abstract Chromosomal rearrangements, such as inversions, have received considerable attention in the speciation literature due to their hampering effects on recombination. However, less is known about how other chromosome fissions and fusions, can affect evolution of reproductive isolation. Here, we used crosses between populations wood white butterfly ( Leptidea sinapis ) with different karyotypes identify genomic regions associated hybrid inviability. By contrasting allele frequencies F 2...
Abstract A major question in evolutionary biology is what drives the diversification of lineages. Rapid, recent radiations are ideal systems for addressing how new species arise because they still show key morphological and ecological adaptations associated with speciation. While most studied have evolved an insular environment, less research has been carried out on continental complex interactions. Melinaea Mechanitis butterflies (Nymphalidae: Ithomiini) rapidly radiated Neotropics. They...
Abstract Gene family expansions and crossing over are two main mechanisms for the generation of novel genetic variants that can be picked up by natural selection. Here, we developed a high-density, pedigree-based linkage map painted lady butterfly ( Vanessa cardui ) – non-diapausing, highly polyphagous species famous its long-distance migratory behavior. We also performed detailed annotations genes interspersed repetitive elements previously genome assembly, characterized species-specific...
Abstract Karyotypes are generally conserved between closely related species and large chromosome rearrangements typically have negative fitness consequences in heterozygotes, potentially driving speciation. In the order Lepidoptera, most investigated ancestral karyotype gene synteny is often across deep divergence, although examples of extensive genome reshuffling recently been demonstrated. The genus Leptidea has an unusual level variation rearranged sex chromosomes, but extent...