A5017851858- Pancreatic and Hepatic Oncology Research
- Cancer Immunotherapy and Biomarkers
- Cancer Genomics and Diagnostics
- Diversity and Career in Medicine
- Esophageal and GI Pathology
- Phagocytosis and Immune Regulation
- Surgical Simulation and Training
- Lung Cancer Research Studies
- Immune cells in cancer
- Dental Education, Practice, Research
- Gallbladder and Bile Duct Disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal Tumor Research and Treatment
- Nanoplatforms for cancer theranostics
- Neuroendocrine Tumor Research Advances
- Minimally Invasive Surgical Techniques
- Intestinal Malrotation and Obstruction Disorders
- Gastroesophageal reflux and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Education and Admissions
- Eosinophilic Esophagitis
- Cardiovascular Issues in Pregnancy
- Clinical Laboratory Practices and Quality Control
- Healthcare professionals’ stress and burnout
- Diverticular Disease and Complications
Methodist Richardson Medical Center
2020-2022
University of North Texas
2021
University of North Texas Health Science Center
2021
Methodist Dallas Medical Center
2020
McGill University
2020
Thomas Jefferson University
2019
University of Arizona
2019
Lankenau Institute for Medical Research
2017-2019
Lankenau Medical Center
2016-2017
Colorectal Surgical Associates
2017
Abstract Purpose: Heritable genetic variations can affect the inflammatory tumor microenvironment, which ultimately cancer susceptibility and clinical outcomes. Recent evidence indicates that IDO2, a positive modifier in disease models, is frequently upregulated pancreatic ductal adenocarcinoma (PDAC). A unique feature of IDO2 humans high prevalence two inactivating single-nucleotide polymorphisms (SNP), affords opportunity to carry out loss-of-function studies directly humans. In this...
We genetically characterized the synaptic role of Drosophila homologue human DCAF12, a putative cofactor Cullin4 (Cul4) ubiquitin ligase complexes. Deletion DCAF12 impairs larval locomotion and arrests development. At neuromuscular junctions (NMJs), is expressed presynaptically in boutons, axons, nuclei motor neurons. Postsynaptically, muscle facilitates Cul4-dependent ubiquitination. Genetic experiments identified several mechanistically independent functions at NMJs. First, presynaptic...
Repair of inguinal hernia is a common procedure, but there lack consensus as to the optimal repair technique along with use mesh and methods fixation. The objective this study was evaluate efficacy safety fibrin sealant for fixation in laparoscopic totally extraperitoneal (TEP) repair.
The Whipple procedure in its current form owes evolution to the groundbreaking and innovative work of giants field surgery. From being a multistep with high morbidity mortality, it is now ubiquitously performed single setting, often offered via minimally invasive approaches. Training perform this an arduous task, different training paradigms vary significantly.The purpose paper share standard method by which surgeon can systematic manner. Using illustrations make steps clearer, authors will...
The Americas Hepato-Pancreato-Biliary Association (AHPBA) Education and Training Committee standardized a Hepatopancreatobiliary (HPB) Surgery Fellowship certification process in 2010. Several classes of fellows have since graduated from HPB, combined Society Surgical Oncology/AHPBA, American Transplant Surgeons/AHPBA fellowships, but there is little information on their career outcomes. We seek to offer long-term data the careers HPB fellowship graduates.A 26-question anonymous survey was...
Background:Minimally invasive esophagectomy (MIE) is becoming increasing popular. Since it was introduced, there has been debate about its safety and efficacy when compared with open esophagectomies (OE). We sought to compare the oncologic outcomes of MIE OE in this study specifically regards margin status nodal retrieval.Methods:Ninety-three patients that underwent (76/93) or (17/93) for esophageal cancer at out institution between January 2013 September 2018 were retrospectively reviewed....
Introduction Several pathophysiologic changes after the Whipple procedure have been well described, but anemia has not. Post-surgical can impede micronutrient absorption. We hypothesize that patients post-pancreatoduodenectomy suffer from iron deficiency anemia.Methods Patients who underwent a pancreatoduodenectomy 2016 to 2018 were retrospectively evaluated. Preoperative, intraoperative, and postoperative data, including hemoglobin (Hb) levels mean corpuscular volume (MCV) as therapies with...
The World Health Organization (WHO) defines intracholecystic papillary neoplasms (ICPNs) as gallbladder lesions of intraductal the bile duct (IPNB). We present a case ICPN that was incidentally diagnosed following cholecystectomy for cholecystitis and cholelithiasis. Abdominal ultrasonography computed tomography showed thickening wall cholelithiasis but were not specific tumor. Histopathological examination revealed an papillary-tubular neoplasm associated with moderately differentiated...
The primary aim of this study is to assess the necessity fundoplication for reflux in patients undergoing Heller myotomy achalasia. secondary safety robotic approach myotomy.This a single institution, retrospective analysis 61 who underwent with or without over 4-year period (January 1, 2015 - December 31, 2019). Symptoms were evaluated using pre-operative and postoperative Eckardt scores at < 2 weeks (short-term) 4 55 months (long-term) postoperatively. Incidence gastroesophageal use...
<p>Table S1. Sequencing primers for IDO2 functional polymorphisms. Table S2. genotype functionality definitions. A three-tier scale describes possible combinations of polymorphisms.</p>
<p>Supplemental legend</p>
<p>Bar graphs (black and white line dot drawing)</p>
<p>Flow cytometry graphs (black and white line dot drawing)</p>
<p>Supplemental survival data (color line graphs)</p>
<p>Table S1. Sequencing primers for IDO2 functional polymorphisms. Table S2. genotype functionality definitions. A three-tier scale describes possible combinations of polymorphisms.</p>
<p>Bar graphs (black and white line dot drawing)</p>
<p>Supplemental survival data (color line graphs)</p>
<p>Flow cytometry graphs (black and white line dot drawing)</p>
<div>AbstractPurpose:<p>Heritable genetic variations can affect the inflammatory tumor microenvironment, which ultimately cancer susceptibility and clinical outcomes. Recent evidence indicates that IDO2, a positive modifier in disease models, is frequently upregulated pancreatic ductal adenocarcinoma (PDAC). A unique feature of <i>IDO2</i> humans high prevalence two inactivating single-nucleotide polymorphisms (SNP), affords opportunity to carry out loss-of-function...