A5064721568- Genomics and Phylogenetic Studies
- Microbial Natural Products and Biosynthesis
- Plant-Microbe Interactions and Immunity
University of Basel
2022
QB3
2022
University of California, Berkeley
2022
Lawrence Berkeley National Laboratory
2022
Polyketide synthases (PKSs) are predominantly microbial biosynthetic enzymes. They assemble highly potent bioactive natural products from simple carboxylic acid precursors. The most versatile families of PKSs organized as assembly lines functional modules. Each module performs one round precursor extension and optional modification, followed by directed transfer the intermediate to next module. While enzymatic domains even modules well understood, higher-order modular architecture PKS...