- Psychosomatic Disorders and Their Treatments
- Action Observation and Synchronization
- Mental Health and Psychiatry
- Schizophrenia research and treatment
- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Face Recognition and Perception
- Neural and Behavioral Psychology Studies
- Psychotherapy Techniques and Applications
- Alzheimer's disease research and treatments
- Alcoholism and Thiamine Deficiency
- Body Image and Dysmorphia Studies
- Cholinesterase and Neurodegenerative Diseases
- Multisensory perception and integration
- Tryptophan and brain disorders
- Virtual Reality Applications and Impacts
- Neurology and Historical Studies
- Bipolar Disorder and Treatment
- Parkinson's Disease Mechanisms and Treatments
- Sex work and related issues
- Computational Drug Discovery Methods
- Hallucinations in medical conditions
- Cannabis and Cannabinoid Research
- Pain Mechanisms and Treatments
- Creativity in Education and Neuroscience
University of Chieti-Pescara
2004-2023
Medical Technologies (Czechia)
2014
University of Catania
2013
Italian Institute of Technology
2012
University of Udine
2004
Catholic University of America
2000
Previous studies suggested that the observation of other individuals' somatosensory experiences also activates brain circuits processing one's own experiences. However, it is unclear whether cortical regions involved with elementary stages touch are in automatic coding affective consequences observed and to which extent they show overlapping activation for self others. In order investigate these issues, present fMRI study, healthy participants either experienced or watched videos depicting...
Social dysfunction has been recognized as an elementary feature of schizophrenia, but it remains a crucial issue whether social deficits in schizophrenia concern the inter-subjective domain or primarily have their roots disturbances self-experience. perception comprises vicarious processes grounding experiential inter-relationship with others well self-regulation allowing to maintain coherent sense self. The present study investigated functional neural basis underlying these is altered...
Self-experience anomalies are elementary features of schizophrenic pathology. Such deficits can have a profound impact on self-other relationship, but how they related through aberrant brain function remains poorly understood. In this functional magnetic resonance imaging (fMRI) study, we provide new evidence for cortical link between self-experience and social cognition in first-episode schizophrenia (FES). As identified previous studies, ventral premotor cortex (vPMC) posterior insula...
The study evaluates the expression and production of cytokines in peripheral blood mononuclear cells patients with Alzheimer disease treated or not acetylcholinesterase inhibitor, which enhances neuronal transmission. Cytokines associated brain inflammation such as interleukin (IL)-1β, IL-6, tumor necrosis factor-α have been implicated regulation amyloid peptide protein synthesis. anti-inflammatory cytokine, IL-4, may suppress activity IL-1β. Patients were assessed for clinical immunologic...
We investigated the efficacy of S‐Adenosyl‐L‐Methionine (SAMe) augmentation in patients with treatment‐resistant depressive disorder (TRD). Thirty‐three outpatients major episode who failed to respond at least 8 weeks treatment two adequate and stable doses antidepressants were treated openly fixed dose SAMe (800 mg) for weeks, added existing medication. The primary outcome measure was change from baseline total score on Hamilton Rating Scale Depression (HAM‐D). Clinical Global Impression...
Abstract Severe restrictive measures were implemented globally to limit the spread of Covid-19 pandemic leading significant lifestyle changes and impacting on both physical mental health citizens. Caught by fear getting sick, some individuals have adopted behaviors which favored development exercise addiction (EA). Our aim was evaluate activity habits risk EA in general Italian population during phase 1 lockdown. The role appearance anxiety (AA), self-compassion, use performance image...
In social life actions are tightly linked with emotions. The integration of affective- and action-related information has to be considered as a fundamental component appropriate understanding. present functional magnetic resonance imaging study aimed at investigating whether an emotion (Happiness, Anger or Neutral) dynamically expressed by observed agent modulates brain activity underlying the perception his grasping action. As control stimuli, participants same either only expressing...
Major Depressive Disorder (MDD) is among the most frequent comorbidities occurring in course of Parkinson's disease (PD), and therefore, PD patients receive antidepressant drugs. Agomelatine a recently introduced drug acting as an MT1/MT2 melatonergic receptor agonist 5HT2C/5HT2B serotonergic antagonist. The aim this case series was to evaluate role agomelatine treatment MDD associated with PD.
Social perception commonly employs multiple sources of information. The present study aimed at investigating the integrative processing affective social signals. Task-related and task-free functional magnetic resonance imaging was performed in 26 healthy adult participants during a task concerning dynamic visual stimuli simultaneously depicting facial expressions emotion tactile sensations that could be either congruent or incongruent. Confounding effects due to valence, inhibitory top-down...
<b><i>Background/Aims:</i></b> Several components of social cognition are compromised in schizophrenia (SCZ) from the early stage illness. In this study we first investigated whether mirror neuron-driven embodied simulation (mnES) is altered first-episode SCZ. Second, tested emotional cues impact on mnES SCZ patients. <b><i>Methods:</i></b> Twenty-two patients and 22 healthy controls (HCs) observed goal-related actions either a neutral or...