A5033646110- Influenza Virus Research Studies
- RNA and protein synthesis mechanisms
- Immune Response and Inflammation
- Monoclonal and Polyclonal Antibodies Research
- Viral Infectious Diseases and Gene Expression in Insects
- Respiratory viral infections research
- RNA Research and Splicing
- Viral Infections and Immunology Research
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
Lankenau Institute for Medical Research
2019
Chang Gung University
2014-2019
Influenza B viruses are antigenically classified into Yamagata and Victoria lineages according to their hemagglutinin (HA) proteins. These two known either appear sequentially or cocirculate in Taiwan.Taiwanese influenza viral HA neuraminidase (NA) sequences between 2003 2014 were determined analyzed. A time-scaled phylogenetic tree was constructed decipher the evolutionary trends of these sequences, reassortment lineages. Positively selected amino acids predicted, demonstrating adaptive...
Hybridoma methods for monoclonal antibody (mAb) cloning are a mainstay of biomedical research, but they hindered by the need to maintain hybridomas in oligoclonal pools during screening. Here, we describe system which specifically capture and display mAbs secrete: On-Cell mAb Screening (OCMS™). In OCMS™, displayed on cell surface can be rapidly assayed expression level binding specificity using fluorescent antigens with high-content (image-based) or flow cytometry. OCMS™ demonstrated...