A5023692128- Neuroscience and Neuropharmacology Research
- Insect and Pesticide Research
- Essential Oils and Antimicrobial Activity
- Bee Products Chemical Analysis
- Memory and Neural Mechanisms
- Neuropeptides and Animal Physiology
- Helicobacter pylori-related gastroenterology studies
- Insect and Arachnid Ecology and Behavior
- Plant and animal studies
- Antibiotic Resistance in Bacteria
- Pharmacological Receptor Mechanisms and Effects
- Medicinal Plants and Neuroprotection
- Receptor Mechanisms and Signaling
- GABA and Rice Research
- Hormonal and reproductive studies
- Bioactive Compounds and Antitumor Agents
- Drug Transport and Resistance Mechanisms
- Ion Transport and Channel Regulation
- Anesthesia and Sedative Agents
- Force Microscopy Techniques and Applications
- Bacterial biofilms and quorum sensing
- Lipid Membrane Structure and Behavior
- Alkaloids: synthesis and pharmacology
- Gastroesophageal reflux and treatments
- Insect Pest Control Strategies
Rudjer Boskovic Institute
2016-2025
Ahvaz Jundishapur University of Medical Sciences
2020
Lorestan University of Medical Sciences
2020
Jackson and Tull (United States)
2020
University of Zagreb
2015-2017
Faculty (United Kingdom)
2017
University of Osijek
2017
College of Agriculture at Križevci
2017
We investigated the mechanisms of anti-Candida action isoquinoline alkaloid berberine, active constituent medically important plants Barberry species. The effects on membrane, morphological transition, synthesis ergosterol and consequent changes in membrane permeability have been studied. Polarization lipid peroxidation level following berberine treatment addressed. Minimal inhibitory concentration (MIC) against C. albicans was 17.75 μg/mL. Cytotoxic effect dependent, sub-MIC concentrations...
To provide new insights in treatment of colitis and ischemia reperfusion rats using stable gastric pentadecapeptide BPC 157.Medication [BPC 157, L-NAME, L-arginine (alone/combined), saline] was bath at the blood deprived colon segment. During reperfusion, medication 157 or saline. We recorded (USB microscope camera) vessel presentation through next 15 min ischemic (IC-rats) (removed ligations) (IC + RL-rats); oxidative stress as MDA (increased (IC- IC RL-rats)) NO levels (decreased...
Several negative factors contribute to a decline in the number of insect pollinators. As novel approach therapy, we hypothesize that EM® for bees could potentially have an important therapeutic and immunomodulatory effect on honey bee colonies. The aim our study was evaluate its impact at individual colony level. This is first appliance commercial probiotic mix PROBIOTIC FOR BEES as economically social insects. sugar syrup with 10% administered by spraying or feeding colonies field...
The aim of this study was to investigate and compare in detail both the antifungal activity vitro (with planktonic biofilm-forming cells) essential oil composition (EOs) naturally growing (OMN) cultivated (OMC) samples Origanum majorana L. (marjoram). analyzed using GC-MS. major constituent EOs carvacrol: 75.3% 84%, respectively. Both oils showed high against clinically relevant Candida spp. with IC50 IC90 less than or equal 0.5 µg mL-1 inhibition biofilm a concentration 3.5 less. Cultivated...
Oxidative stress and lipid peroxidation play important roles in numerous physiological pathological processes, while the bioactive products of peroxidation, hydroperoxides reactive aldehydes, act as mediators redox signaling normal malignant cells. Many types cancer, including osteosarcoma, express altered pathways. Such pathways protect cancer cells from cytotoxic effects oxidative stress, thus supporting transformation, eventually anticancer therapies associated with stress. In this...
Copper, a transition metal with essential cellular functions, exerts neurotoxic effects when present in excess by promoting production of reactive oxygen species (ROS). The aim the study was to investigate potential benefits flavonoid quercetin against copper-induced toxicity. Results obtained MTT assay indicate that are determined severity toxic insult. In moderately injured P19 neuronal cells, concomitant treatment 150 μ M improved viability preventing ROS formation, caspase-3 activation,...
We compared the chemical composition, antioxidant and antimicrobial activity of two propolis extracts: one obtained with nonaqueous polyethylene glycol, PEG 400 (PgEP), other ethanol (EEP). analyzed total phenolic content (TPC) concentrations ten markers HPLC-UV: caffeic acid, p-coumaric trans-ferulic trans-cinnamic kaempferol, apigenin, pinocembrin, chrysin, CAPE, galangin. Antioxidant was tested using DPPH FRAP assay, assessed through minimum inhibitory (MICs) biofilm eradication...
We revealed that the stable gastric pentadecapeptide BPC 157, a useful peptide therapy against isoprenaline myocardial infarction, as well reinfarction, may follow counteraction of recently described occlusion-like syndrome, induced peripherally and centrally, which was for first time in isoprenaline-treated rats. 157 (10 ng/kg, 10 µg/kg i.p.), L-NAME (5 mg/kg L-arginine (200 i.p.) were given alone or together at (i) 30 min before or, alternatively, (ii) 5 after (75 150 s.c.). At 75 s.c., we...
Nosema ceranae can cause major problems, such as immune suppression, gut epithelial cell degeneration, reduced honeybee lifespan, or suddenly colony collapse. As a novel approach in therapy, we hypothesize the stable gastric pentadecapeptide BPC 157 to control N. invasions apiary conditions: treated sugar syrup (0.25 L supplemented with 0.1 μg/ml 157), well pure syrup; control), was administered colonies feeders situated under roof of hives, during 21 consecutive days, at end beekeeping...
Propolis is a popular subject of research worldwide due to its therapeutic potential. The antimicrobial activity propolis appears be promising but depends on many variables related origin such as the content phenolics and flavonoids. To address this issue with Croatian propolis, which has two major origins (Mediterranean continental), we exposed bacteria (Escherichia coli Staphylococcus aureus) yeasts (Candida albicans Aspergillus niger) different concentrations (two-fold microdilution...