- Abdominal Surgery and Complications
- Gastroesophageal reflux and treatments
- Clinical Nutrition and Gastroenterology
- Congenital Diaphragmatic Hernia Studies
- Helicobacter pylori-related gastroenterology studies
- Drug Transport and Resistance Mechanisms
- Atrial Fibrillation Management and Outcomes
- Reconstructive Surgery and Microvascular Techniques
- Esophageal and GI Pathology
- Dental Anxiety and Anesthesia Techniques
- Pediatric Pain Management Techniques
- Genital Health and Disease
- Intestinal and Peritoneal Adhesions
- Antibiotic Resistance in Bacteria
- Microscopic Colitis
- Cardiovascular and Diving-Related Complications
- Diabetes Treatment and Management
- Colorectal Cancer Surgical Treatments
- Cardiovascular Issues in Pregnancy
- Quality and Safety in Healthcare
- Foreign Body Medical Cases
- Tracheal and airway disorders
- Biomedical Research and Pathophysiology
- Drug-Induced Adverse Reactions
- Biliary and Gastrointestinal Fistulas
Queen Elizabeth Hospital Birmingham
2024
University of Zagreb
2017-2022
University Hospital Dubrava
2021
Faculty (United Kingdom)
2017
University of Osijek
2017
Rudjer Boskovic Institute
2017
To provide new insights in treatment of colitis and ischemia reperfusion rats using stable gastric pentadecapeptide BPC 157.Medication [BPC 157, L-NAME, L-arginine (alone/combined), saline] was bath at the blood deprived colon segment. During reperfusion, medication 157 or saline. We recorded (USB microscope camera) vessel presentation through next 15 min ischemic (IC-rats) (removed ligations) (IC + RL-rats); oxidative stress as MDA (increased (IC- IC RL-rats)) NO levels (decreased...
To study the counteraction of perforated cecum lesion using BPC 157 and nitric oxide (NO) system agents.Alongside with agents' application (after 1 min, medication (/kg, 10 mL/2 min bath/rat) includes: (10 μg), L-NAME (5 mg), L-arginine (100mg) alone or combined, saline baths (controls)) on rat perforate injury, we continuously assessed gross reappearance vessels (USB microcamera) quickly propagating toward defect at surface, contraction, bleeding attenuation, MDA- NO-levels in tissue 15...
We show the complex syndrome of occluded superior sagittal sinus, brain swelling and lesions multiple peripheral organs in rat. Recovery goes centrally peripherally, with stable gastric pentadecapeptide BPC 157, which alleviated vascular occlusion disturbances, rapidly activating alternative bypassing pathways. Assessments were gross recording, venography, ECG, pressure, microscopy, biochemistry. The increased pressure portal caval hypertension, aortal hypotension, arterial venous...
Recently, the stable gastric pentadecapeptide BPC 157 was shown to counteract major vessel occlusion syndromes, i.e., peripheral and/or central occlusion, while activating particular collateral pathways. We induced abdominal compartment syndrome (intra-abdominal pressure in thiopental-anesthetized rats at 25 mmHg (60 min), 30 (30 40 and 50 (15 min) esketamine-anesthetized (25 for 120 min)) as a model of multiple syndrome. By improving function venous system with 157, we reversed chain...
Abstract Aim Most Thoracic Surgery inpatients undergo chest drain insertion during their hospitalisation. Some patients, however, experience extended stays or readmission after removal. Our departmental guidelines recommend removing stitches 5-7 days post-drain This audit aims to evaluate and enhance our practice in this regard. Method retrospective study included patients who remained as were readmitted on day-7 following the removal of a that required stitches. The was conducted two...
Aim We focused on perforated defect in stomach and caecum, NO‐tissue levels rats the therapy with stable gastric pentadecapeptide BPC 157. Effective lesion caecum as well ischemic colitis, ischemia reperfusion, 157 rapidly activates vessels “running” toward (stomach perforation (Gastroenterology 2017; 152, Issue 5, Supplement 1, S889–S890; Gastroenterology S890–S891) or to bypass vessel obstruction (ischemic colitis)(World Journal of Gastroenterology, press, 2017) largely attenuates lesions...
Background: Vulvar carcinoma most often occurs on the outer surface area of female genitalia. The vulva is skin that surrounds urethra and vagina, including clitoris labia. It quite rare cancer reproductive system accounts for 3-4% all genitourinary tract neoplasms. Though it can occur at any age, vulvar common in older adults. When present young women mostly associated with human papillomavirus (HPV)–related dysplasia. histology squamous cell vulva. Case study: This report presents a...
Aim We introduce pentadecapeptide BPC 157 therapy in rats with cysteamine induced‐terminal ileitis, 1 h, month, 2 months. counteracted gross hyperemia, edema, erosion, bleeding, and, microscopically, significant loss of villous architecture, and shortening villae severe lymphocytic infiltrate. counteracts various lesions the whole GI‐tract free radicals formation (Curr Pharm Des 2018;24:1990–2001), tested ulcerative colitis trials now multiple sclerosis 2018;24:1990–2001). Previously,...
Goal:The aim of this study was to evaluate the community-based prevalence atrial fibrillation (AF) in a geographically well-defined population central part Croatia. Methods:We searched hospital electronic health records Clinic Internal Medicine (IMD) and Emergency Department (ED) University Hospital Dubrava (UHD) for patients older than 20 years age diagnosed with AF period from January 1, 2007 2017.We then eliminated all who have died before 2017 or did not residence within official...