A5103027005- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Antioxidant Activity and Oxidative Stress
- Medical Imaging Techniques and Applications
- Medicinal Plant Pharmacodynamics Research
- Sirtuins and Resveratrol in Medicine
- Flavonoids in Medical Research
- Radiomics and Machine Learning in Medical Imaging
- Medical Research and Treatments
- Maternal and Perinatal Health Interventions
- Plant Gene Expression Analysis
- Natural product bioactivities and synthesis
- Advanced Radiotherapy Techniques
Sichuan Agricultural University
2024
Dalian Maternal and Child Health Hospital
2009-2021
Background.Increasing radiosensitivity of cancer cells can enhance the efficacy cervical treatment.Objectives.This study evaluated potential roles and mechanism baicalein in regulating vitro. Materials methods.Real-time quantitative polymerase chain reaction (RT-qPCR) was used to assess miR-183 expression End1/E6E7 cells, Hela irradiated with X-ray (0 Gy, 1 3 5 10 Gy).Cell Counting Kit-8 (CCK-8) method measured cell viability after regulation, or RO8191 treatment.Apoptosis rates were...
Long non-coding RNA (lncRNA) KCNQ1 and opposite strand/antisense transcript 1 (KCNQ1OT1) have been validated to be carcinogenic in several cancers. However, the role of KCNQ1OT1 regulating malignant biological behavior radiotherapy resistance cervical cancer (CC) remains largely unknown. Quantitative real time-polymerase chain reaction (qRT-PCR) was carried out detect miR-491-5p expression CC tissues cells. Pyruvate kinase M1/2 (PKM2) detected by Western blot. cell proliferation, movement,...
Objective To observe the efficacy and safety of three drugs(dinoprostone suppositories,misopmstol oxytocin) to promote cervieal ripening.Methods A randomized control study method was used.The 180 primipara divided into 3 groups.Group A:dinoprostone suppositories,Group B:low-dose misoprostol,Group C:oxytocin.The maternal cervical Bishop score drugs being used before after 4,8,12 h compared between groups,as well as labor situation,the rate fetal distress neonatal asphyxia drugs.Results The...
Objective To study the short-term efficacy of computed tomography (CT)-guided iodine-125(125I) radioactive seed implantation in treatment hypoxic tumors. Methods Twenty-two patients treated with 125I our department from 2014 to 2016 were divided into hypovascular tumor group (hypoxic group, n=12) and hypervascular (non-hypoxic n=10) based on hemodynamics solid evaluated by color Doppler ultrasound. The enhanced CT images loaded three-dimensional particle planning system for...