A5012286710- Thermoregulation and physiological responses
- Textile materials and evaluations
- Building Energy and Comfort Optimization
- Urban Heat Island Mitigation
- Infrared Thermography in Medicine
- Cancer Research and Treatments
- Nanoplatforms for cancer theranostics
- Advanced Sensor and Energy Harvesting Materials
- Color perception and design
- Flood Risk Assessment and Management
- Thermal Radiation and Cooling Technologies
- Exercise and Physiological Responses
- Infection Control and Ventilation
- Climate Change and Health Impacts
- IoT and Edge/Fog Computing
- Acoustic Wave Phenomena Research
- Caching and Content Delivery
- Bacteriophages and microbial interactions
- Material Properties and Processing
- Tropical and Extratropical Cyclones Research
- Silk-based biomaterials and applications
- Radiative Heat Transfer Studies
- Silkworms and Sericulture Research
- Cancer, Hypoxia, and Metabolism
- Gut microbiota and health
Wuhan University
2018-2024
Guangdong University of Technology
2018-2024
Tianjin Normal University
2023-2024
Dalian University of Technology
2023
Jilin University
2022
Hainan Tropical Ocean University
2022
Soochow University
2015-2020
Donghua University
2010-2015
Beihang University
2013-2014
Hong Kong Polytechnic University
2013
As an emerging cancer treatment strategy, ferroptosis is greatly restricted by excessive glutathione (GSH) in tumor microenvironment (TME) and low reactive oxygen species (ROS) generation efficiency. Here, this work designs self-assembled copper-alanine nanoparticles (CACG) loaded with glucose oxidase (GOx) cinnamaldehyde (Cin) for situ activated enzymatic cascade-enhanced immunotherapy. In response to GSH-rich acidic TME, CACG allows effectively co-deliver Cu2+ , Cin, GOx into tumors....
The excessive lactate in the tumor microenvironment always leads to poor therapeutic outcomes of chemotherapy. In this study, a self-driven bioreactor (defined as SO@MDH, where SO is Shewanella oneidensis MR-1 and MDH MIL-101 metal–organic framework nanoparticles/doxorubicin/hyaluronic acid) rationally constructed via integration doxorubicin (DOX)-loaded (MOF) nanoparticles with sensitize Owing intrinsic tropism electron-driven respiration SO, biohybrid SO@MDH could actively target colonize...
The differential tumor environment guides various antitumor drug delivery strategies for efficient cancer treatment. Here, based on the special bacteria-enriched environment, we report a different strategy by targeting bacteria inhabiting sites. With tissue microarray analysis, it was found that amounts displayed significant differences between and normal tissues. Bacteria-targeted mesoporous silica nanoparticles decorated with bacterial lipoteichoic acid (LTA) antibody (LTA-MSNs) could...
Clinical treatment efficacy of oral bacterial therapy has been largely limited by insufficient gut retention probiotics. Here, we developed a bioorthogonal-mediated delivery strategy for enhancing probiotics colonization modulating adhesion between and inhabitants. Metabolic amino acid engineering was applied to metabolically incorporate azido-decorated d-alanine into peptidoglycans inhabitants, which could enable in situ bioorthogonal conjugation with dibenzocyclooctyne (DBCO)-modified Both...
AbstractThis study aimed to examine the effectiveness of a hybrid personal cooling system (PCS) in mitigating body heat stain while exercising hot environment. Eight subjects underwent two trials: PCS and CON (i.e. no cooling). All trials were conducted at an air temperature 36 ± 0.5 °C RH = 59 5%. The key findings demonstrated that could significantly reduce core temperature, mean skin heart rate physiological strain index during both exercise recovery periods (p < 0.05). Subjective...
Due to inherent differences in cellular composition and metabolic behavior with host cells, tumor-harbored bacteria can discriminatorily affect tumor immune landscape. However, the mechanisms by which intracellular antigen presentation process between cells antigen-presenting (APCs) are largely unknown. The invasion of attenuated Salmonella VNP20009 (VNP) into is investigated an attempt made modulate this modifying positively charged polymers on surface VNP. It found that non-toxic chitosan...
A novel design of personal cooling clothing incorporating additional insulation sandwiched between phase change materials (PCMs) and outer layer is proposed. Performance four systems including with only PCMs, PCMs (PCM + INS), ventilation fans (HYB), (HYB INS) was investigated. Effect on performance in terms human physiological perceptual responses also examined. Human trials were carried out a hot environment (i.e. 36 °C, RH = 59%). Results showed that significantly lower mean skin/torso...
The chemotherapy efficacy of nanodrugs is restricted by poor tumor targeting and uptake. Here, an engineered biohybrid living material (designated as EcN@HPB) constructed integrating paclitaxel BAY-876 bound human serum albumin (HPB) with Escherichia coli Nissle 1917 (EcN). Due to the inherent tropism EcN, EcN@HPB could actively target site competitively deprive glucose through bacterial respiration. Thus, would be used alternative nutrient source for metabolism, which significantly promotes...
Wearable strain sensors play a pivotal role in real-time human motion detection and health monitoring. Traditional fabric-based sensors, typically with positive Poisson's ratio, face challenges maintaining sensitivity comfort during due to conflicting resistance changes different directions. In this work, high-performance stretchable are developed based on graphene-modified auxetic fabrics (GMAF) for smart wearable devices. The proposed GMAF negative ratio achieved through commercially...
Abstract In the past few years, metal‐organic frameworks (MOFs) with high surface area, large pore volume, and tunable composition have attracted much research attention due to their applications in fields of drug delivery cancer treatment. this review, authors summarize recent developments field MOFs‐based multifunctional nanoplatforms for therapy.
Global alterations in the metabolic network provide substances and energy to support tumor progression. To fuel these processes, extracellular matrix (ECM) plays a dominant role supporting mass transport providing essential nutrients. Here, we report fibrinogen thrombin based coagulation system construct an artificial ECM (aECM) for selectively cutting-off flux. Once micro-wound is induced, cascaded gelation of aECM can be triggered besiege tumor. Studies on cell behaviors metabolomics...
Computation offloading is a popular approach for reducing energy consumption of mobile devices by computation to remote servers. Most the prior work focuses on limited form part from device single server. However, with advent and development cloud computing, it more promising reduce multiple servers/sites. This paper proposes an Energy-Efficient Multisite Offloading (EMSO) algorithm, which formulates multiway partitioning problem as 0-1 Integer Linear Programming (ILP) problem. Moreover, our...
A technique named the Microcolor system was developed to detect microbes and diagnose diseases based on changes in microbiota signatures.