A5004637001- Inhalation and Respiratory Drug Delivery
- Advanced Drug Delivery Systems
- Antimicrobial Peptides and Activities
- Nanoparticle-Based Drug Delivery
- Microencapsulation and Drying Processes
- Drug Solubulity and Delivery Systems
- Advanced Photocatalysis Techniques
- Advanced Nanomaterials in Catalysis
- Burn Injury Management and Outcomes
- Antibiotic Resistance in Bacteria
- RNA Interference and Gene Delivery
- Nanoparticles: synthesis and applications
- Copper-based nanomaterials and applications
- Nausea and vomiting management
- Tea Polyphenols and Effects
- Antibiotics Pharmacokinetics and Efficacy
- Neuropeptides and Animal Physiology
- Ginseng Biological Effects and Applications
- Toxin Mechanisms and Immunotoxins
- Cystic Fibrosis Research Advances
- Advancements in Transdermal Drug Delivery
- Air Quality and Health Impacts
- Berberine and alkaloids research
- Graphene and Nanomaterials Applications
- Cellular transport and secretion
International Islamic University, Islamabad
2024
Jiangsu University
2024
Mahatma Gandhi Memorial Hospital
2024
Farooq Hospital
2024
Institute of Nano Science and Technology
2016-2023
Indian Institute of Science Education and Research Mohali
2018-2022
India Habitat Centre
2016-2021
Panjab University
2020-2021
Center for Nano Science and Technology
2019
National Institute of Pharmaceutical Education and Research
2014-2016
The tumour site-specific stimulus responsiveness of smart drug delivery systems gives a unique system for effective therapeutic with reduced toxic effects conventional chemotherapeutic drugs. In this work, matrix metalloproteinase-2 (MMP-2)-responsive mesoporous silica nanoparticles (MSNs) were synthesized and assessed "self-actuating" on-demand controlled cancer therapy. MMPs are members protease enzymes that generally overexpressed in cancerous tissues all stages cancer. MSNs have...
Growing rates of tuberculosis (TB) superbugs are alarming, which has hampered the progress made to-date to control this infectious disease, and new drug candidates few. Epigallocatechin gallate (EGCG), a major polyphenolic compound from green tea extract, shows powerful efficacy against TB bacteria in vitro studies. However, therapeutic molecule is limited due poor pharmacokinetics low bioavailability following oral administration. Aiming improve treatment outcomes EGCG therapy, we...
The critical time window between the incidence of frostbite injury and initiation treatment in remote snowbound areas is a determining factor for an effective therapeutic response. It emergency condition challenging to treat due poor vascularity affected body parts, it requires immediate action. In addition cold trauma-induced tissue damage, inflammatory mediators majorly contribute pathologic aggravations. We have designed evaluated topical "nano-spray gel (NSG)" formulation, which based on...
Cardamonin (CRD), a chalconoid obtained from several medicinal plants of Zingiberaceae family, had shown promising potential in cancer prevention and therapy. For further development better pharmacological elucidation, we performed series vitro vivo studies to characterize its preclinical pharmacokinetics. The study samples were analyzed using validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) high performance chromatography-ultra violet (HPLC-UV) methods. CRD is partially...
Effect of silver decoration on hollow silica and its antimicrobial properties.
The eradication of several pathogenic drug resistant "Superbug" such as Escherichia coli became difficult especially in chronic infections using existing antibiotics due to the emergence antibiotic resistance. Owing their unique antibacterial properties, host defense peptides (HDP) have gained significant attention combat colonization bacteria. This study aims designing delivery systems for HHC10 peptide target bacteria inside cells might be a promising approach by protecting from...
Inorganic drugs, especially polyoxometalate-based hybrids, are expected to be developed as promising future metallodrugs. Herein, an organic-inorganic hybrid solid based on pyridine-2-carboxylic acid or picolinic (pic), [(Cu(pic)2)2(Mo8O26)]·8H2O (1), was synthesized. A single-crystal structure of a possesses discrete β-type octamolybdate cluster that supramolecularly aggregates with {Cu2(pic)4}4- complex and eight lattice water molecules. The study indicates the is stable in aqueous medium...