Giovanni Maria Comacchio

ORCID: 0000-0002-3166-1843
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About
Contact & Profiles
Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Myasthenia Gravis and Thymoma
  • Pleural and Pulmonary Diseases
  • Tracheal and airway disorders
  • Lung Cancer Treatments and Mutations
  • Pituitary Gland Disorders and Treatments
  • Transplantation: Methods and Outcomes
  • Organ Transplantation Techniques and Outcomes
  • Thyroid and Parathyroid Surgery
  • Meningioma and schwannoma management
  • Lung Cancer Research Studies
  • Cancer Immunotherapy and Biomarkers
  • Peptidase Inhibition and Analysis
  • Head and Neck Cancer Studies
  • Renal Transplantation Outcomes and Treatments
  • Salivary Gland Tumors Diagnosis and Treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Medical Imaging and Pathology Studies
  • Congenital Diaphragmatic Hernia Studies
  • Esophageal and GI Pathology
  • Esophageal Cancer Research and Treatment
  • Neuroendocrine Tumor Research Advances
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Trauma Management and Diagnosis
  • Chronic Obstructive Pulmonary Disease (COPD) Research

University of Padua
2016-2025

Thoracic Surgery Foundation
2024

Azienda Ospedaliera di Padova
2020

ORCID
2019

University of Pisa
2016

Innsbruck Medical University
2016

Robotic thymectomy for early-stage thymomas has been recently suggested as a technically sound and safe approach. However, due to lack of data on long term results, controversy still exists regarding its oncological efficacy. In this multi-institutional series collected from four European Centres with high volumes robotic procedures, we evaluate the results after robot-assisted thoracoscopic thymoma.Between 2002 2014, 134 patients (61 males 73 females, median age 59 years) clinical diagnosis...

10.3978/j.issn.2225-319x.2015.08.13 article EN PubMed 2016-01-01

Abstract OBJECTIVES Robotic thymectomy has been suggested and considered technically feasible for thymic tumours. However, because of small-sample series the lack data on long-term results, controversies still exist surgical oncological results with this approach. We performed a large national multicentre study sought to evaluate early outcomes after robot-assisted thoracoscopic in epithelial METHODS All patients tumours operated through robotic approach between 2002 2022 from 15 Italian...

10.1093/ejcts/ezae178 article EN European Journal of Cardio-Thoracic Surgery 2024-04-25

Minimally invasive techniques seem to be promising alternatives open approaches in the surgical treatment of early-stage thymoma, although there are controversies because lack data on long-term results. The aim study was evaluate and oncological results after robotic thymectomy for thymoma compared median sternotomy.Between 1982 2017, 164 patients with (Masaoka I II) were operated by sternotomy (108 patients) or approach (56 patients). Duration surgery, amount blood loss, complications,...

10.1093/ejcts/ezy075 article EN European Journal of Cardio-Thoracic Surgery 2018-02-13

ABSTRACT Background Evidence supporting robotic thymectomy for myasthenia gravis is generally based on small sample‐size studies, heterogeneous in patient selection and reporting outcomes. Therefore, this study was conducted to assess the surgical neurological outcomes of myasthenic patients identify prognostic factors associated with symptoms' remission through a large cohort operated 20 years' period. Methods A retrospective analysis prospectively maintained database all undergoing between...

10.1111/ene.70147 article EN cc-by European Journal of Neurology 2025-04-01

Background: Pancoast tumors are a rare subset of lung cancers that require multimodal approach (induction chemoradiotherapy and surgery), best performed in highly specialized centers. This study analyzes the outcomes prognostic factors patients treated at high-volume center over an extended period. Methods: We retrospectively reviewed 43 who underwent surgery for tumors, following induction treatment between 2005 2023. Survival was estimated using Kaplan–Meier method, Cox proportional...

10.3390/jcm14082758 article EN Journal of Clinical Medicine 2025-04-17

Spread through air spaces (STAS) is a novel invasive pattern of lung cancer associated with poor prognosis in non-small cell (NSCLC). We aimed to investigate the incidence STAS surgical series adenocarcinomas (ADCs) resected our thoracic surgery unit and identify association other clinicopathological characteristics. retrospectively enrolled patients stage cT1a-cT2b who underwent resection between 2016 2022. For each case, comprehensive pathologic report was accessible which included...

10.1097/pas.0000000000002199 article EN The American Journal of Surgical Pathology 2024-03-04

Background and aim: Liver transplantation (LT) is an established treatment for hepatocellular carcinoma (HCC). HCC recurrence occurred between 8 to 20% of patients lung the most frequent site. Pulmonary metastases resection (PMR) prolongs survival, however in LT-setting impact on survival unclear. To shed new lights this topic, we report experience three Italian LT Centers. Methods: All consecutive transplanted Centers, who developed pulmonary metastasis from (PM-HCC), as first metastasis,...

10.3389/fonc.2020.00381 article EN cc-by Frontiers in Oncology 2020-04-15

The usefulness of digital chest drain is still debated. We are carrying out a study to determine if the use system compared with traditional reduces duration drainage. To evaluate safety, benefit, or futility this trial we planned current interim analysis.An analysis on preliminary data from ongoing investigator-initiated, multicenter, interventional, prospective randomized trial. Original protocol number: (NCT03536130). main endpoint was overall complications; secondary endpoints were...

10.1186/s13019-021-01567-y article EN cc-by Journal of Cardiothoracic Surgery 2021-07-05

Osimertinib is considered the standard-of-care for previously-untreated EGFR mutant advanced non-small cell lung cancer (NSCLC). Oncogene driver screening in early NSCLC not standard practice. A real-world study has been designed order to investigate optimal testing frequency and timing mutations clinical practice.The present observational, retrospective evaluated diagnostic-therapeutic pathway outcomes of 225 patients with stage I-III NSCLC, particular reference EGFR-mutant subgroup.Prior...

10.3389/fonc.2022.909064 article EN cc-by Frontiers in Oncology 2022-06-29

Background: The involvement of mediastinal great vessels is common in advanced stage thymic tumors, which makes their surgical resection challenging. Moreover, the impact vascular on oncological prognosis still unclear. aim this study to investigate and outcomes a population patients operated for tumors. Methods: A retrospective analysis four hundred sixty-five undergoing (Masaoka III–IV) tumors single high-volume center was performed. One forty-four met inclusion criteria were eligible...

10.3390/cancers13133355 article EN Cancers 2021-07-04

To date, no combined immunoscore has been evaluated for prognostic stratification of early stage non-small-cell lung cancer (NSCLC). The main goal this study was to investigate the impact programmed death ligand 1 (PD-L1) expression and different immune cell components (CD4+, CD8+ T-lymphocytes, CD68+ macrophages) in NSCLC patients, distinguishing peritumoral (PT) intratumoral (IT) localizations. secondary aim identify a optimize patients.This retrospective included surgical specimens from...

10.3389/fonc.2020.564915 article EN cc-by Frontiers in Oncology 2020-09-25

In the last decades, use of video-assisted thoracoscopic surgery (VATS) lobectomy for treatment early stage non-small cell lung cancer is continuously growing. This mainly due to development more advanced surgical devices, rising incidence peripheral tumors and also favored by increased reliability preoperative staging techniques. Despite this progress, postoperative unexpected nodal upstaging still a relevant issue. Aim study identify possible predictors in patients affected cT1-3N0 NSCLC...

10.21037/jovs.2017.12.23 article EN Journal of Visualized Surgery 2018-01-17
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