About
Contact & Profiles
A5031546064
Research Areas
- Mitochondrial Function and Pathology
- Genetics, Aging, and Longevity in Model Organisms
- Cyclopropane Reaction Mechanisms
- Chemical synthesis and alkaloids
- Adipose Tissue and Metabolism
- Synthesis and pharmacology of benzodiazepine derivatives
- Amyotrophic Lateral Sclerosis Research
- Epigenetics and DNA Methylation
- Fibroblast Growth Factor Research
- Coenzyme Q10 studies and effects
University of Helsinki
2017-2023
Center for Excellence in Basic Sciences
2017
10.1016/j.cmet.2017.07.007
article
EN
publisher-specific-oa
Cell Metabolism
2017-08-01
10.1016/j.cmet.2019.08.019
article
EN
publisher-specific-oa
Cell Metabolism
2019-09-12
Energetic insufficiency, excess production of reactive oxygen species (ROS), and aberrant signaling partially account for the diverse pathology mitochondrial diseases. Whether interventions affecting ROS, a regulator stem cell pools, could modify somatic homeostasis remains unknown. Previous data from DNA mutator mice showed that increased ROS leads to oxidative damage in erythroid progenitors, causing lifespan-limiting anemia. Also unclear is how ROS-targeted affect terminally...
10.26508/lsa.202302036
article
EN
cc-by
Life Science Alliance
2023-09-01
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