A5007103202- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Pharmaceutical studies and practices
- Pharmaceutical Practices and Patient Outcomes
- Patient Safety and Medication Errors
- Sepsis Diagnosis and Treatment
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Medical Imaging Techniques and Applications
- Cardiac Arrest and Resuscitation
- Healthcare Decision-Making and Restraints
- Hemodynamic Monitoring and Therapy
- Anesthesia and Neurotoxicity Research
- Neonatal Respiratory Health Research
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Diabetes Management and Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Diabetes and associated disorders
- Platelet Disorders and Treatments
- Radiopharmaceutical Chemistry and Applications
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cardiac Imaging and Diagnostics
- Epilepsy research and treatment
- Pharmacy and Medical Practices
- Alcoholism and Thiamine Deficiency
Brigham and Women's Hospital
2010-2021
Harvard University
2019
Anna Needs Neuroblastoma Answers
2014-2018
Universität Hamburg
2017
University Medical Center Hamburg-Eppendorf
2017
Yale New Haven Hospital
2015
Boston Children's Hospital
2012
UMass Memorial Medical Center
2012
Northeastern University
2010
Abstract Introduction While propofol is associated with an infusion syndrome (PRIS) that may cause death, the incidence of PRIS unknown. Determining and frequency PRIS-related clinical manifestations are key steps prior to completion any controlled studies investigating PRIS. This prospective, multicenter study sought determine in a large cohort critically ill adults prescribed propofol. Methods Critically from 11 academic medical centers administered for [>/=] 24 hours were monitored at...
Sleep is known to be poor in the hospital. Patients frequently request pharmacological sleep aids, despite risk of altered mental status (delirium) and falls. Little about scope aid use hospitalized patients.We performed a single center, retrospective review all patients admitted general adult (age >18 years) medical surgical units tertiary care center during recent 2-month period (January 2013-February 2013). Review electronic medication administration system was assess for medications...
Management of pain and sedation therapy is a vital component optimizing patient outcomes; however, the ideal pharmacotherapy regimen has not been identified in postoperative cardiac surgery population. We sought to evaluate efficacy safety outcomes between mechanically ventilated patients receiving dexmedetomidine versus propofol upon arrival intensive care unit (ICU). conducted single center, descriptive study clinical practice at 20-bed ICU tertiary academic medical center. Adult...
Delirium occurs in the intensive care unit and identification is often performed using a validated assessment tool such as Confusion Assessment Method for Intensive Care Unit (CAM-ICU) patients. The CAM-ICU has three ratings: positive, negative, unable to assess (UTA). Patients may be assigned UTA when it inappropriate given level of sedation or medical condition. purpose this study evaluate rate documentations.A single-center prospective observational analysis was evaluating documentations...
Background: There are limited data regarding the incidence of adverse events associated with administering lacosamide by intravenous push (IVP) compared IV piggyback (IVPB). Objective: The objective this analysis was to compare safety profile, including cardiovascular effects, sedative and site reactions IVP IVPB administration. Methods: A retrospective pre/post cohort comparing patients who received via conducted. Safety end points included hypotension, bradycardia, medication-related...
Flolan (iFLO) and Veletri (iVEL) are 2 inhaled epoprostenol formulations. There is no published literature comparing these formulations in critically ill patients with refractory hypoxemia.To compare efficacy, safety, cost outcomes who received either iFLO or iVEL for hypoxic respiratory failure.This was a retrospective, single-center analysis of adult, mechanically ventilated receiving improvement oxygenation. The primary end point the change PaO2/FiO2 ratio after 1 hour pulmonary...
The optimal monitoring strategy for anticoagulation management in extracorporeal membrane oxygenation (ECMO) remains a clinical controversy. Extracorporeal Life Support Organization Anticoagulation Guidelines suggest that multiple assays may be needed but do not specify preferred strategy.In adult ECMO patients, which demonstrate the highest correlation with unfractionated heparin (UFH) dose requirements?We performed retrospective chart review of patients cannulated to between February 2013...
No previous studies exist examining implementation of an institution-wide guideline and order set for hyperglycemic emergencies (diabetic ketoacidosis [DKA] hyperosmolar state [HHS]).Evaluate the impact institutional emergencies.This retrospective descriptive study evaluated patients with a diagnosis DKA or HHS. Two time periods were evaluated: phase 1 (PRE) assessed practice preguideline implementation, 2 (POST) postguideline introduction.A total 172 (91 PRE 81 POST) included in analysis....
Calcium gluconate is preferred over calcium chloride for intravenous (IV) repletion of deficiencies in the inpatient setting. In setting a national shortage IV gluconate, our institution implemented compounded admixture administration. The objective this analysis to evaluate peripheral infusion site safety admixtures adult inpatients. A total 222 patients, encompassing 224 admissions, from April June 2011 were retrospectively reviewed. Sterile preparations 5% dextrose (600 mg/250 mL and 300...