Mustafa Aytek Şimşek

ORCID: 0000-0002-3217-4836
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About
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Research Areas
  • Cardiac electrophysiology and arrhythmias
  • Acute Myocardial Infarction Research
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Disease and Adiposity
  • ECG Monitoring and Analysis
  • Heart Failure Treatment and Management
  • Inflammatory Biomarkers in Disease Prognosis
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac Arrest and Resuscitation
  • Coronary Interventions and Diagnostics
  • Atrial Fibrillation Management and Outcomes
  • Cardiovascular Health and Disease Prevention
  • Heme Oxygenase-1 and Carbon Monoxide
  • Cardiac, Anesthesia and Surgical Outcomes
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cardiac pacing and defibrillation studies
  • Thermal Regulation in Medicine
  • Bariatric Surgery and Outcomes
  • Circular RNAs in diseases
  • COVID-19 Clinical Research Studies
  • Cerebrovascular and Carotid Artery Diseases
  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Immunology Research
  • Heart rate and cardiovascular health

Yeditepe University
2018-2024

Orient-Institut Istanbul
2024

Yeditepe University Hospital
2015-2024

Dokuz Eylül University
2015

State Hospital
2013

Although ST-segment elevation (STE) has been used synonymously with acute coronary occlusion (ACO), current STE criteria miss nearly one-third of ACO and result in a substantial amount false catheterization laboratory activations. As many other electrocardiographic (ECG) findings can reliably indicate ACO, we sought whether new ACO/non-ACO myocardial infarction (MI) paradigm would better identification the patients who need reperfusion therapy.A total 3000 were enrolled STEMI, non-STEMI...

10.1016/j.ijcha.2020.100603 article EN cc-by-nc-nd IJC Heart & Vasculature 2020-07-30

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic in clinical practice, and there an increasing trend its prevalence general population. Recent studies have demonstrated increased risk atrial fibrillation (AF) NAFLD. However, information on mechanism AF NAFLD lacking. Impaired conduction important factor pathophysiology AF. We aimed to investigate properties patients with by tissue Doppler echocardiography. Fifty-nine ultrasound diagnosed without diagnosis...

10.1177/0161734615595015 article EN Ultrasonic Imaging 2015-07-08

QRS fragmentation (fQRS) and distortion were separately shown to be related increased cardiovascular mortality morbidity. To our knowledge, no study so far evaluated both parameters together in ST segment elevation myocardial infarction (STEMI). The main goal of is find out if fQRS can help us determine high-risk STEMI patients, the success reperfusion.Two hundred forty-eight eligible patients with acute that underwent coronary angiography consecutively between January 1, 2009, July 2011,...

10.1111/anec.12265 article EN Annals of Noninvasive Electrocardiology 2015-02-02

Left ventricular diastolic dysfunction has a significant impact on perioperative morbidity and mortality, its incidence is high in elderly individuals. Anesthetic agents may impair function, which increase the of complications. The aim this prospective, clinical, phase 4 study was to investigate effects remifentanil left ventricle (LV) function patients with dysfunction. performed 30 spontaneously breathing subjects (aged 60-80 years)

10.1186/s12871-024-02425-9 article EN cc-by BMC Anesthesiology 2024-02-01

Objective Aortic pulse wave velocity (AoPWV), one of the parameters showing arterial stiff ness, has been investigated in diff erent patient groups as a predictor cardiovascular diseases. The purpose our study is to investigate correlation between AoPWV and coronary artery disease (CAD) its severity.Methods results One hundred three patients who were not diagnosed with CAD but scheduled have angiography (CAG) suspicion included study. PWV was measured tonometry device before CAG. Patients...

10.1080/ac.70.3.3080636 article EN Acta Cardiologica 2015-06-01

Abstract Background It may sometimes be difficult to differentiate subtle ST ‐segment elevation ( STE ) due anterior myocardial infarction MI from benign variant BV . Recently, two related formulas were proposed for this purpose. However, they have never been tested in an external population. Materials and methods Consecutive patients May 2017 January 2018, who admitted with the diagnosis of acute STEMI , enrolled. Electrocardiograms systematically reviewed only ones included. First 200...

10.1111/anec.12568 article EN Annals of Noninvasive Electrocardiology 2018-06-25

Left ventricular hypertrophy (LVH) involves increased muscular mass of the left ventricle due to cardiomyocyte size and is caused by cardiomyopathies. Several microRNAs (miRNAs) have been implicated in processes that contribute heart disease. This study aimed examine miRNA-133, miRNA-26 miRNA-378 as candidate biomarkers define prognosis patients with LVH.The group consisted 70 who were diagnosed LVH 16 unaffected individuals served control group. Real-time polymerase chain reaction (RT-PCR)...

10.21873/invivo.12417 article EN In Vivo 2021-01-01

We investigated the relationship between NT-ProBNP and mortality in a general population-based cohort.A total of 2021 out 4650 participants from previously published HAPPY study were included. Mean follow-up was 84.5 ± 10.4 months. After adjusting for risk factors, high levels LogNT-proBNP predicted all-cause death (HR: 3.23; 95% CI: 2.20-4.75; p < 0.001) cardiovascular 3.85; 2.37-6.26; 0.001). Regression analysis revealed that an independent predictor 2.85; 1.91-4.24; 3.02; 1.84-4.95;...

10.2217/bmm-2018-0120 article EN Biomarkers in Medicine 2018-09-07

10.5543/tkda.2015.90228 article cc-by-nc-nd Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology 2024-01-01

10.1016/j.jcin.2017.08.010 article EN publisher-specific-oa КАРДИОЛОГИЯ УЗБЕКИСТАНА 2017-11-16

diac structure and function in obese patients. This study was an examination of the short-term effects sleeve gastrectomy on body measurements diastolic function.A total 41 consecutive patients who were scheduled to undergo a procedure included study. Baseline echocardiographic follow-up counterpart data, including excess weight loss percentages, recorded.The mean age 42.85+-11.47 years. Of total, 21 (51.1%) female. The mass index (BMI) 44.86+-5.62 kg/m². duration 91.24+-44.48 days....

10.5543/tkda.2018.95994 article EN cc-by-nc-nd Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology 2018-01-01

Myocarditis is associated with increased morbidity and mortaity in patients Covid-19 infection. Little known about the true nature exact pathogenesis of myocardial involvement these patients. 44 year old patient admitted exertional dyspnea. He had previous coronary artery bypass surgey received hemodialysis for lupus nephritis. was diagnosed infection 1 month ago. Echocardiography revealed decreased left ventricular ejection fraction global longitudinal strain (GLS). Coronary computerized...

10.22541/au.170666072.21671654/v1 preprint EN Authorea (Authorea) 2024-01-31

In a subgroup of patients with inferior myocardial infarction (MI), both the right coronary artery (RCA) and circumflex (Cx) show potentially culprit lesions, angiography may be insufficient to determine which is responsible for clinical presentation. Although many electrocardiographic (ECG) algorithms have been proposed identifying infarct-related in MI, it unclear whether current discriminative power identify real these patients.The diagnosis acute MI underwent were enrolled study. The...

10.14744/anatoljcardiol.2020.24583 article EN cc-by-nc The Anatolian Journal of Cardiology 2020-01-01

The aim of this study was to determine adiponectin and copeptin levels that might be prognostic for cardiovascular mortality (CvsM) in ST-segment elevation myocardial infarction (STEMI) patients who had percutaneous coronary intervention (PCI).Patients underwent PCI between November 2010 April 2011 were enrolled followed more than eight years. baseline, demographic angiographic findings, in-hospital follow up, laboratory results including levels, echocardiographic data the evaluated.There 78...

10.5830/cvja-2023-046 article EN PubMed 2023-10-04

1388 Sudden cardiac death etiology were analyzed using Chi-square test.Multiple logistic regression was used to identify predictors of unfavorite outcome.Results: During the study period, a total 24,605 deaths transferred, among them, 4927 (20.0%) OHCA with mean age 73.5 years, 60.3% male, and 88.1% possible etiology.The proportions in increasing from 2011 2016 (87.0% 97.4%, P<0.001, Fig 1 A).The rates StH, SE return spontaneous circulation (ROSC) when ambulance arrived (and decline BAED...

10.1093/eurheartj/ehx493.p6430 article EN European Heart Journal 2017-08-01

Abstract Introduction Although ST-segment elevation (STE) has been used synonymously with acute coronary occlusion (ACO), current STE criteria miss nearly one-third of ACO and cause a substantial amount false catheterization laboratory activations. Purpose We sought whether new ACO/non-ACO myocardial infarction (MI) paradigm would result in better identification the patients who need reperfusion therapy. Methods A total 3000 were enrolled STEMI, non-STEMI control groups. combined endpoint...

10.1093/ehjci/ehaa946.1755 article EN European Heart Journal 2020-11-01

Background: The authors investigated the relationship between weight loss after sleeve gastrectomy and change in atrial electromechanical delay values. Methods: A total of 41 patients were included. primary end point was any effect on parameters. Results: mean body 25.50 ± 11.07 kg. There a significant correlation interatrial left intra-atrial delays (Pearson's coefficient: 0.575 0.871, respectively; p < 0.001). Only significantly related to (regression 0.707; 0.01). Conclusion: In this...

10.2217/fca-2021-0093 article EN Future Cardiology 2022-03-17
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