A5060829596- Cerebral Palsy and Movement Disorders
- Balance, Gait, and Falls Prevention
- Muscle activation and electromyography studies
- Botulinum Toxin and Related Neurological Disorders
- Stroke Rehabilitation and Recovery
- Infant Development and Preterm Care
- Vestibular and auditory disorders
- Diabetic Foot Ulcer Assessment and Management
- Children's Physical and Motor Development
- Heart Rate Variability and Autonomic Control
- Prosthetics and Rehabilitation Robotics
- Occupational Health and Performance
- Gait Recognition and Analysis
- Video Surveillance and Tracking Methods
- Lysosomal Storage Disorders Research
- Child Nutrition and Feeding Issues
- Injury Epidemiology and Prevention
- Cardiomyopathy and Myosin Studies
- Genetic Neurodegenerative Diseases
- Neurogenetic and Muscular Disorders Research
University of Delaware
2021-2024
Mitchell Institute
2024
Texas A&M University
2024
Parents' Place of Maryland
2022
National Institutes of Health Clinical Center
2017-2021
National Institutes of Health
2020
Connectivity of somatosensory cortex (S1) and cerebellum with the motor (M1) is critical for balance control. While both S1-M1 cerebellar-M1 connections are affected aging, implications altered connectivity control not known. We investigated relationship between standing in middle-aged older adults. Our secondary objective was to investigate how cognition balance. results show that greater related postural sway during standing. This may be indicative an increase functional recruitment...
Individuals with cerebral palsy (CP) have deficits in processing of somatosensory and proprioceptive information. To compensate for these deficits, they tend to rely on vision over proprioception single plane upper lower limb movements standing. It is not known whether this also applies walking, an activity where the threat balance higher. Through study, we used visual perturbations understand how individuals without CP integrate input walking control. Additionally, probed mechanisms driving...
Recumbent stationary cycling is a potential exercise modality for individuals with cerebral palsy (CP) that lack the postural control needed upright exercises. Functional electrical stimulation (FES) of lower extremity muscles can help such reach intensities are required aerobic benefits. The aim this study was to examine effect and without FES assistance no-intervention group on cardiorespiratory fitness children CP. Thirty-nine participants were randomized underwent an 8-week FES-assisted...
Functional electrical stimulation (FES) walking interventions have demonstrated improvements to gait parameters; however, studies were often confined of one or two muscle groups. Increased options such as number groups targeted, timing delivery, and level are needed address subject-specific deviations. We aimed demonstrate the feasibility using a FES system with increased during in children cerebral palsy (CP). Three physical therapists designed individualized programs for six CP target...
Clinical evaluation of balance has relied on forceplate systems as the gold standard for postural sway measures. Recently, based wireless inertial sensors have been explored, mostly in adult population, an alternative given their practicality and lower cost. Our goal was to validate body-worn against measures typically developing children during tests quiet stance.
Gait analysis has applications in medical diagnosis, biometrics, and development of therapeutic rehabilitation interventions (such as orthotics, prosthetics, exoskeletons). While offering accurate measurements, gait laboratories are expensive, not scalable, easily accessible. In a pandemic-afflicted world, where telemedicine is crucial, there need for subject-driven data remote collection. This study proposed purely procedure reproducible scalable collection real-life data. To evaluate the...
Abstract Aim To investigate the relationship between somatosensory deficits, specifically ankle and hip joint position sense, two-point discrimination, vibration on (1) responses to visual perturbations during walking (2) response improvements while receiving a sensory-centric treatment, i.e., stochastic resonance (SR) stimulation, in individuals with without cerebral palsy (CP). Methods Twenty-eight (14 CP, 14 age-and sex-matched controls) walked virtual reality cave perturbations. We...
This is the first study to objectively measure gait, balance, and upper limb coordination in a group of patients with NPC1 compare results age gender matched controls. also report effect sizes these measures. Spatiotemporal gait analysis, static dynamic posturography, reaching motion analysis were performed. The findings showed that subjects had statistically significant deficits on 12 out 16 parameters investigated compared controls, large for all but 1 parameter. When ranking variables...
Smoothness is a hallmark of skilled, coordinated movement, however, mathematically quantifying movement smoothness nuanced. Several metrics exist, each having its own limitations and may be specific to particular motion such as upper limb reaching. To date, there no consensus on which metric the most appropriate for assessing cycling in children with cerebral palsy (CP). We evaluated ability four preexisting metrics, dimensionless jerk, spectral arc length measure, roughness index,...
Abstract Introduction: Individuals with cerebral palsy (CP) compensate for deficits in somatosensory processing by relying on visual input over proprioception balance control. Upweighting, i.e., increasing reliance proprioception, helps free up vision high-level use like navigation and obstacle avoidance. We hypothesize that children CP will be able to upweight reduce if their is improved. A promising technique improve the of Stochastic Resonance (SR) stimulation, which uses random,...
Stationary cycling is a practical exercise modality in children with cerebral palsy (CP) that lack the strength for upright exercises. However, there of robust, sensitive metrics can quantitatively assess motor control during cycling. The purpose this brief report was to characterize differences CP and typical development by developing novel quantify smoothness rhythm. Thirty one spastic diplegic 10 cycled on stationary cycle. Cycling measured cross-correlating crank angle an ideal pattern...
Instrumented gait mat systems have been regarded as one of the gold standard methods for measuring spatiotemporal parameters. However, their portable walkways confine walking to a restricted area and limit number cycles collected. Wearable inertial sensors are potential alternative that allow more natural behavior fewer space restrictions. The objective this pilot study was establish concurrent validity body-worn against walkway system in older children.Twenty-one participants (10 males)...
Wearable systems can evaluate a subject's gait without the need to meet therapist. Some of these wearables are in form smartphone built-in sensors. Gait characteristics give us knowledge health status individuals with movement disorders. In this study, we designed gyroscope-based application for quantifying parameters through sensor. This method uses custom created algorithm measuring person's manner walking. The outcome is an inexpensive tracking prognosis disease and monitoring patient...
Introduction. Spinal and bulbar muscular atrophy (SBMA) is a neuromuscular disorder that leads to progressive weakness of extremity muscles. Dynamic balance during functional tasks has not been reported in people with SBMA. Objectives. (1) To evaluate the ability safely complete forward lunge (FL), step quick turn (SQT), up over (SUO), (2) determine presence severity dynamic impairments by comparing performance normative data, (3) investigate relationship between lower strength each task....