Christine Firk

ORCID: 0000-0002-3310-0011
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About
Contact & Profiles
Research Areas
  • Child and Adolescent Psychosocial and Emotional Development
  • Maternal Mental Health During Pregnancy and Postpartum
  • Stress Responses and Cortisol
  • Neuroendocrine regulation and behavior
  • Tryptophan and brain disorders
  • COVID-19 and Mental Health
  • Infant Health and Development
  • Biochemical effects in animals
  • Child Abuse and Trauma
  • Autism Spectrum Disorder Research
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Mental Health Research Topics
  • Attention Deficit Hyperactivity Disorder
  • Child and Adolescent Health
  • Health disparities and outcomes
  • Attachment and Relationship Dynamics
  • Mental Health Treatment and Access
  • Breastfeeding Practices and Influences
  • Early Childhood Education and Development
  • Adolescent Sexual and Reproductive Health
  • Functional Brain Connectivity Studies
  • Adipose Tissue and Metabolism
  • Protein Hydrolysis and Bioactive Peptides
  • Digital Mental Health Interventions
  • Obsessive-Compulsive Spectrum Disorders

Catholic University of Applied Sciences of North Rhine – Westphalia
2020-2024

Catholic University of Applied Sciences
2020-2022

RWTH Aachen University
2013-2022

Universitätsklinikum Aachen
2013-2022

Klinik und Poliklinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters
2013-2020

Hussman Institute for Autism
2017

University of California, San Francisco
2017

University of California, Los Angeles
2017

University of California, Davis
2017

American Academy of Child and Adolescent Psychiatry
2016-2017

Social-Emotional competencies evolve early in life. For example, emotion regulation is learned primarily the context of mother-child interaction, which may allow for maternal influences to shape children's social-emotional development. The aim current study was longitudinally examine determinants development a community-based sample first-time mothers (N = 61, aged 22-39 years). Specifically, we used structural equation modeling how difficulties and subclinical depression directly...

10.1002/imhj.21765 article EN Infant Mental Health Journal 2019-02-07

Reduced brain serotonin function is acknowledged as a vulnerability factor for affective disturbances. Since the production of limited by availability its plasma dietary amino acid precursor tryptophan (TRP), beneficial effects tryptophan-rich alpha-lactalbumin whey protein (ALAC) have recently been studied. The ALAC remain rather modest, and alternative sources may be more effective.We tested whether hydrolyzed (HPROT) has greater on TRP/large neutral acids (LNAA) ratio mood than intact in...

10.1007/s00213-008-1254-0 article EN cc-by-nc Psychopharmacology 2008-07-22

Dyadic interactions between children and depressed mothers have been characterized as less synchronous with lower maternal sensitivity, fostering an inharmonious, insecure attachment relationship mother child. Thus, these may experience enhanced early life stress are at higher risk of disturbed socioemotional development. Recently, this association has also found in women mild depressive symptoms. However, potential confounding effects mother's history own rearing experiences or infant...

10.1159/000447597 article EN Psychopathology 2016-01-01

It has been suggested that an early deficit in the human mirror neuron system (MNS) is important feature of autism. Recent findings related to simple hand and finger movements do not support a general dysfunction MNS Studies investigating facial actions (e.g., emotional expressions) have more consistent, however, mostly relied on passive observation tasks. We used new variant compatibility task for assessment automatic mimicry responses allowed simultaneous control attention stimuli....

10.1002/aur.1654 article EN Autism Research 2016-06-28

Correcting for motion is an important consideration in infant functional near-infrared spectroscopy studies. We tested the performance of conventional correction methods and compared probe data quality metrics collected at different ages (5, 7, 12 months) during stimulus presentation (video versus live). While 5-month-olds had slower maximum head speed than 7- or 12-month-olds, hemodynamic response recovery errors were similar across ages. Data was also between video live presentation....

10.1117/1.nph.5.1.015004 article EN Neurophotonics 2018-02-13

Polymorphisms of the serotonin transporter gene (5-HTTLPR) may be associated with increased vulnerability to acute tryptophan depletion (ATD) and depression especially following stressful life events. The aim present study was investigate effects ATD in subjects different 5-HTTLPR profiles before after stress exposure on affective cognitive–attentional changes. Eighteen homozygotic short alleles (S′/S′) 17 long (L′/L′) participated a double-blind, placebo-controlled, crossover design measure...

10.1007/s00213-008-1428-9 article EN cc-by-nc Psychopharmacology 2008-12-15

A functional polymorphism within the serotonin transporter gene (5-HTTLPR) has been reported to modulate emotionality and risk for affective disorders. The short (S) allele less efficacy than long (L) associated with enhanced emotional reactivity. One possible contributing factor high in S carriers may be inefficient use of cognitive strategies such as reappraisal regulate responses. aim present study was test whether 5-HTTLPR genotype modulates neural correlates emotion regulation. To...

10.1093/scan/nsr091 article EN Social Cognitive and Affective Neuroscience 2012-02-17

Infant crying elicits caregiving behaviors, which are indispensable for fulfilling the infant's needs. However, infant can also evoke negative and angry feelings in caregiver. Therefore, parents need to regulate their own emotions sensitively respond distressed infant. Thus, current study aims examine neural basis of emotional reactivity regulation response using functional MRI primiparous mothers (N = 26). Amygdala activation was negatively associated with maternal sensitivity nonhostility...

10.1037/emo0000373 article EN Emotion 2017-11-20

Abstract Background The ongoing Covid-19 pandemic not only threatens physical health, but also affects the mental health of people. Yet, consequences do affect all members society equally. We therefore assessed burden individuals who are at increased risk severe illness from compared to low during first lockdown (March, 2020) in Germany. Furthermore, we investigated variables mediating effect being an individual serve on depression. Methods Adult German residents ( n = 2.369) provided...

10.1186/s12889-022-13593-z article EN cc-by BMC Public Health 2022-06-14

The measures taken to contain the COVID-19 pandemic have led significant changes in people's daily lives. This paper examines substance use during first lockdown (March-July 2020) and investigates mental health burdens users with increased consumption of alcohol, nicotine or tetrahydrocannabinol (THC) Germany compared unchanged reduced consumption.In a cross-sectional online survey, 2369 people were asked about their Germany.Of participants, 28.5% alcohol use, 28.8% tobacco products, 20.6%...

10.3390/ijerph191912801 article EN International Journal of Environmental Research and Public Health 2022-10-06

Background Previous studies have reported that cognitive deficits occur in patients with anorexia nervosa ( AN ) and these may represent a predisposition towards developing or perpetuate the disorder. Specifically, dysfunctional implicit learning contribute to development of highly resistant dieting behaviours are fundamental persistence Thus, aims this study were (a) investigate sequence adolescent before after weight recovery (b) elucidate associated neural mechanisms acute relative...

10.1111/jcpp.12384 article EN Journal of Child Psychology and Psychiatry 2015-01-26

Children of adolescent mothers present a high-risk group for child neglect and maltreatment. Previous findings suggest that early interventions can reduce maltreatment by improving the quality mother-child interaction, particularly maternal sensitivity. The aim current study is to evaluate effects intervention program using home visits video-feedback regarding interaction (STEEP-b) plus psychiatric treatment mother in cases where mental illness compared with TAU (treatment as usual, is,...

10.1186/s13063-015-0747-5 article EN cc-by Trials 2015-05-26

Individuals with a family history of depression may be more likely to develop due an innate vulnerability their serotonergic system. However, even though constitute risk factor in the development depression, it does not seem sufficient cause depressive episode. Based on previous data, is suggested that stress mediating factor. This study examined role serotonin (5-HT) coping individuals or without depression. Nineteen healthy first-degree relatives patients (FH+) and 19 controls (FH−) were...

10.1007/s00213-008-1125-8 article EN cc-by-nc Psychopharmacology 2008-06-12

Abstract Social work students experience high levels of stress, which makes them vulnerable to stress-related disorders such as depression. Attachment security has been associated with better stress regulation . Another factor that is closely attachment mentalization, i.e., the ability reflect about one's own and others’ mental states, may also influence way people cope stress. The main aim study was investigate impact mentalization on depression, anxiety in social students. 460 completed...

10.1007/s10615-023-00882-2 article EN cc-by Clinical Social Work Journal 2023-07-13

Abstract Background Recent studies report that LGBTQ + people have experienced high levels of mental health problems during COVID-19-related social distancing. Given the well-established association between isolation and health, main aim current study was to investigate differences in (perceived) support individuals compared heterosexual, cisgender explore whether hypothesized higher burden is (partly) mediated by or support. Methods N = 531 participants indicating belonging community 1826...

10.1186/s40359-023-01265-5 article EN cc-by BMC Psychology 2023-08-29
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