A5071712221- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Pelvic and Acetabular Injuries
- Spine and Intervertebral Disc Pathology
- Orthopaedic implants and arthroplasty
- Bone fractures and treatments
- Hip disorders and treatments
- Hip and Femur Fractures
- Shoulder Injury and Treatment
- Tendon Structure and Treatment
- Total Knee Arthroplasty Outcomes
- Pleural and Pulmonary Diseases
- Botulinum Toxin and Related Neurological Disorders
- Orthopedic Surgery and Rehabilitation
- Shoulder and Clavicle Injuries
- Cerebral Palsy and Movement Disorders
- Trauma Management and Diagnosis
- Foot and Ankle Surgery
- Sports injuries and prevention
- Cardiac, Anesthesia and Surgical Outcomes
- Vascular Procedures and Complications
- Elbow and Forearm Trauma Treatment
- Nerve Injury and Rehabilitation
- Pneumothorax, Barotrauma, Emphysema
- Venous Thromboembolism Diagnosis and Management
Great North Children's Hospital
2017-2025
Royal Victoria Infirmary
2013-2024
Northumbria Healthcare NHS Foundation Trust
2015-2024
North Tyneside General Hospital
2014-2021
Newcastle University
2021
British Columbia Children's Hospital
2020-2021
Queen's Medical Centre
2012-2020
Setting Scoliosis Straight Foundation
2020
Shriners Hospitals for Children - Philadelphia
2020
Rady Children's Hospital-San Diego
2020
Spinal fusion remains the gold standard in treatment of idiopathic scoliosis. However, anterior vertebral body tethering (AVBT) is gaining widespread interest, despite limited data on its efficacy. The aim our study was to determine clinical efficacy AVBT skeletally immature patients with scoliosis.All consecutive scoliosis treated enrolled a longitudinal, multicentre, prospective database between 2013 and 2016 were analyzed. All by one two surgeons working at independent centres. Data...
Study Design. Analysis of explanted MAGnetic Expansion Control (MAGEC) growing rods. Objective. To analyze MAGEC rods used in management early onset scoliosis and identify the mode failure such cases. Summary Background Data. Magnetically controlled are increasingly as option choice for scoliosis. However, being more complex than conventional they perhaps likely to succumb multifarious modes. In addition, metallosis has been reported around failed Methods. Explanted from seven UK spinal...
Prospective case series.Determine the efficacy of anterior vertebral body tethering (AVBT) in skeletally immature patients.The value AVBT is currently unclear given paucity available data.Consecutive patients with idiopathic scoliosis were treated between 2012 and 2018 by one two surgeons working at independent centers followed up for >2 years. Data collected prospectively supplemented retrospectively where necessary. Outcomes measured preoperatively, first erect radiograph (FE), 1-year...
Background Understanding the cell functionality during disease progression or drugs’ mechanism are major challenges for precision medicine. Predictive models describing biological phenotypes can be challenging to obtain, particularly in scenarios where sample availability is limited, such as case of rare diseases. Here we propose a new method that reproduces fibroadipogenic expansion occurs muscle wasting. Methods We used immortalized progenitor cells (FAPs) and differentiated them into...
The Nottingham Hip Fracture Score (NHFS) was developed to assess the risk of death following a fracture hip, based on pre-operative patient characteristics. We performed an independent validation NHFS, assessed degree geographical variation that exists between different units within United Kingdom and attempted define NHFS level is associated with high mortality. calculated retrospectively for consecutive patients presenting hip two hospitals in England. observed 30-day mortality each cohort...
Study Design. Laboratory analysis of explanted MAGnetic Expansion Control (MAGEC) growing rods. Objective. The aim this study was to measure the force produced by MAGEC rods compared with new and assess influence clinical variables. Summary Background Data. are increasingly used in early-onset scoliosis. Some data available describing structure rods, but date, no has assessed their function. Methods. Explanted were received from seven UK one Danish center. on activation external remote...
Study Design. Laboratory analysis of explanted MAGnetic Expansion Control (MAGEC) rods. Objective. The aim this study was to identify the in vivo lengthening MAGEC Summary Background Data. Little data is available regarding achieved by Methods. Cases were identified from largest series independently analyzed growth rods determined distance between first “growth mark” and actuator. instrumented spinal calculated for each construct. Constructs considered functional if all could lengthen with...
Abstract Becker muscular dystrophy (BMD) is characterised by fiber loss and expansion of fibrotic adipose tissue. Several cells interact locally in what known as the degenerative niche. We analysed muscle biopsies controls BMD patients at early, moderate advanced stages progression using Hyperion imaging mass cytometry (IMC) labelling single sections with 17 markers identifying different components muscle. developed a software for analysing IMC images studied changes composition spatial...
Study Design. Analysis of explanted MAGnetic Expansion Control (MAGEC) growing rods. Objective. The aim this study was to quantify the rate locking pin breakage in MAGEC rods and compare with manufacturer's data. Summary Background Data. On June 25, 2019, NuVasive released an Urgent Field Safety Notice stating that manufactured before March 26, 2015 had a higher than expected 5%. For made on or after date, no breakages occurred. Methods. From our independent explant database 139 supplied...
Prospective cohort study.Prospectively compare patient-reported as well clinical and radiologic outcomes after anterior or posterior surgery for right thoracic adolescent idiopathic scoliosis (AIS) in a single center by the same surgeons.Anterior spinal instrumentation arthrodesis are both well-established treatments of AIS. The majority studies comparing 2 approaches have focused on radiographic outcomes. There remains paucity prospectively gathered surgical approaches.Forty-two consecutive...
Aims The interaction between surgical lighting and laminar airflow is poorly understood. We undertook an experiment to identify any effect contemporary lights have on flow recommend practical strategies limit negative effects. Materials Methods Neutrally buoyant bubbles were introduced into the field of a simulated setup for routine total knee arthroplasty in theatre. Patterns observed number remaining above over time identified. Five different configurations assessed. Data analysed using...
Dislocation of the acromioclavicular joint is a relatively common injury and number surgical interventions have been described for its treatment. Recently, synthetic ligament device has become available successfully used, however, like other non-native solutions, compromise must be reached when choosing non-anatomical locations their placement. This cadaveric study aimed to assess effect different clavicular anchorage points Lockdown on reduction dislocations, suggest an optimal location. We...
Surgical reconstruction of the dislocated acromioclavicular joint often requires exposure and instrumentation coracoid. This carries risks to surrounding neurovascular structures. We present a safe simple technique primary fixation joint, relying on mechanical principles biological repair, without need for metalwork. By avoiding coracoid we hope this approach will appeal general orthopedic surgeon. have found that is suited both acute chronic dislocation.
We present the case of an immunocompetent man who presented with multiple and progressive cranial nerve palsies. The cause was found to be aspergillosis petrous bone, arising as a result chronic fungal otitis media. Despite treatment local excision systemic anti-fungal therapy, he died after suffering subarachnoid haemorrhage. Diagnosis rests upon prompt radiological imaging acquisition tissue for histological examination culture but cannot made without awareness condition.