- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Systemic Lupus Erythematosus Research
- Spondyloarthritis Studies and Treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Lymphoma Diagnosis and Treatment
- Orthopedic Infections and Treatments
- Multiple Sclerosis Research Studies
- Pregnancy-related medical research
- Bone and Joint Diseases
- Musculoskeletal Disorders and Rehabilitation
- Chronic Lymphocytic Leukemia Research
- Orthopedic Surgery and Rehabilitation
- Systemic Sclerosis and Related Diseases
- Tuberculosis Research and Epidemiology
- Orthopaedic implants and arthroplasty
- Inflammatory Bowel Disease
- Workplace Health and Well-being
- Adolescent and Pediatric Healthcare
- Renal Diseases and Glomerulopathies
- Motivation and Self-Concept in Sports
- Autoimmune Bullous Skin Diseases
- Gastroesophageal reflux and treatments
- Microscopic Colitis
- HER2/EGFR in Cancer Research
Ghent University Hospital
2022
Reinier de Graaf Hospital
2007-2020
Haga Hospital
2012
Leiden University Medical Center
2012
Reade
2012
Amsterdam UMC Location Vrije Universiteit Amsterdam
2009
Amsterdam University Medical Centers
2009
Abstract Objective To compare the effectiveness of 2 Internet‐based physical activity interventions for patients with rheumatoid arthritis (RA). Methods A total 160 physically inactive RA who had a computer Internet access were randomly assigned to an program individual guidance, bicycle ergometer, and group contacts (individualized training [IT] group; n = 82) or providing only general information on exercises (general [GT] 78). Outcome measures included quantity (questionnaire monitor),...
<h3>Background</h3> COBRA (for 'COmbinatie therapie Bij Rheumatoide Artritis') combination therapy is effective for the treatment of rheumatoid arthritis (RA), but long-term safety unknown. This study evaluates survival, comorbidities and joint damage in original trial cohort. <h3>Methods</h3> In trial, 155 patients with early RA were treated sulfasalazine (SSZ) monotherapy (SSZ group) or a step-down prednisolone, methotrexate (MTX) SSZ (COBRA group). The current 11-year follow-up invited...
Abstract Objective A sufficient level of physical activity is important in reducing the impact disease rheumatoid arthritis (RA) patients. According to self‐determination theory, achievement and maintenance related goal setting ownership, which can be supported by health professionals. Our objective was examine association between extent RA patients 1) believe that a set themselves (autonomous regulation) or others (coerced 2) feel rheumatologists (autonomy supportiveness). Method random...
Abstract Objective Work disability is a major consequence of inflammatory rheumatic conditions. Evidence regarding the effectiveness interventions aimed at prevention or reduction work in diseases limited. We conducted randomized controlled trial to investigate multidisciplinary job‐retention vocational rehabilitation (VR) program patients with condition who were risk for job loss. Methods A total 140 chronic randomly assigned either VR (n = 74) usual outpatient care (UC) 66). Patients group...
Abstract Objective To investigate the effectiveness of 4 different treatment strategies for recent‐onset rheumatoid arthritis (RA) on 2‐year patient‐reported outcomes, including functioning and quality life. Methods A total 508 patients with RA were randomly assigned to 1) sequential monotherapy, 2) step‐up combination therapy, both starting methotrexate, 3) initial a tapered high‐dose prednisone, or 4) therapy methotrexate infliximab. Treatment was adjusted every 3 months if Disease...
<h3>Objectives:</h3> Osteoporosis is a well-known extra-articular phenomenon in patients with uncontrolled, long-standing rheumatoid arthritis (RA). In the present study, extent of osteoporosis and reduced bone mineral density (BMD) disease-related demographic factors that are associated BMD were examined recently diagnosed, active RA. <h3>Methods:</h3> total hip lumbar spine was measured using dual-energy <i>x</i> ray absorptiometry 381 diagnosed RA, who had never been treated DMARDs or...
To assess the engagement in and satisfaction with an Internet-mediated physical activity intervention individual supervision patients rheumatoid arthritis (RA).The studied was one of two strategies aimed at enhancing RA that were being compared a randomized controlled trial. A total 82 patients, all experienced using Internet e-mail registered three different rheumatology out-patient clinics, randomly allocated to individualized (52 weeks). They had access personal schedules received by...
We describe the usage of various assistive devices and identify factors associated with in patients rheumatoid arthritis (RA). A cross-sectional, multicentre study was performed three outpatient rheumatology clinics Netherlands. Two hundred forty RA participated study. The main measures were questionnaires a semi-structured interview regarding possession 21 common ISO9999 categories orthopaedic footwear, personal care, mobility, household adaptations for housing. Potential included...
Despite the proven health benefits, patients with rheumatoid arthritis (RA) are found to be less physically active than their healthy peers. The aim of this study was examine what extent and how physical activity, defined as any bodily movement resulting in energy expenditure, is currently promoted by care providers RA they perceive competencies educational needs. For cross-sectional study, Dutch rheumatologists, rheumatology clinical nurse specialists, expert therapists were sent a postal...
Objectives. To compare the prevalence of and predictors for sustained drug-free remission in two cohorts patients with recent-onset RA treated DAS-driven therapy or non-DAS-driven therapy. Methods. Sustained was assessed after 5 years follow-up 508 (DAS ≤ 2.4) a randomized treatment cohort, 424 who received prospective inception cohort. The design cohort required systematic joint assessments restart Predictors were identified by univariable multivariable logistic regression each separately...
Objectives. To investigate the maintenance of physical activity 12 months after two 1-year Internet-based interventions in patients with RA.
To evaluate the role of purpose in life among people with rheumatoid arthritis (RA), a questionnaire comprising Purpose Life test (PIL) and dimension Psychological Well-Being (PWB-pil) was sent to random sample 300 patients RA. Additional questions comprised sociodemographic disease characteristics, physical, mental social functioning, coping (Coping rheumatic stressors questionnaire), quality (RAND-36). Associations between on one side two measures other associations physical dimensions...
To compare the effectiveness and acceptability of silver ring splints (SRS) commercial prefabricated thermoplastic (PTS) in treating swan neck deformities patients with rheumatoid arthritis (RA).Consecutive RA a mobile deformity were included randomized, crossover trial. In 2 different sequences, used both for 4 weeks, washout period weeks. Afterward, preferred splint another 12 The primary outcome measure was dexterity measured Sequential Occupational Dexterity Assessment (SODA). Secondary...
<h3>Objective:</h3> To assess the duration and probability of maintaining low disease activity once a score (DAS) is achieved in recent onset rheumatoid arthritis (RA) patients. <h3>Methods:</h3> The BeSt study randomised trial comparing four different treatment strategies patients with onset, active RA. Treatment adjustments were mandatory as long DAS was >2.4. If ⩽2.4, continued after 6 months, tapered to maintenance dose. We analysed thrice-monthly calculations order ⩽2.4....
To identify hand function problems and the reasons for choosing a specific finger splint in patients with rheumatoid arthritis (RA) swan neck deformities. A qualitative study was performed alongside randomized, controlled cross-over trial comparing effectiveness of two types splints (the silver ring [SRS] prefabricated thermoplastic [PTS]) 50 RA Questions on patients' main problem type were at baseline after using each splint. The analyses included identification meaning units (sub)concepts...
Abstract Objective To evaluate the implementation of an intensive group exercise program in patients with rheumatoid arthritis (RA). Methods In 4 regions The Netherlands, Rheumatoid Arthritis Patients Training was implemented on a limited scale. Evaluation using RE‐AIM model included: Reach, proportion target population participating; Efficacy, effects muscle strength, aerobic capacity, functional ability, and psychological functioning; Adoption, adoption by stakeholders; Implementation,...
Abstract Introduction This study aimed to compare the engagement in moderate- and vigorous-intensity PA axSpA patients with without current physical therapy (PT). Methods In this cross-sectional study, a survey, including PT treatment (yes/no) PA, using ‘Short QUestionnaire ASsess Health-enhancing PA’ (SQUASH), was sent 458 from three Dutch hospitals. From SQUASH, proportions meeting aerobic recommendations (≥ 150 min/week moderate-, ≥ 75 or equivalent combination; yes/no) were calculated....
Abstract Objectives Physiotherapy is recommended in the management of people with axial Spondyloarthritis (axSpA), new insights into its preferred content and dosage evolving. This study aimed to describe use preferences regarding individual group physiotherapy among axSpA. Methods A cross-sectional survey was conducted axSpA living Netherlands (NL) Switzerland (CH). Results 713 participated (56.7% male, median age 55 years, ASAS-Hi-score 4.2). Response rates were 45% (n = 206) NL 29% CH...
<h3>Objectives</h3> To evaluate the 1 year clinical outcomes of remission steered therapy in early arthritis, initially with methotrexate (MTX) and a tapered high dose prednisone, case followed by tapering medication to zero, no randomization two combination strategies. <h3>Methods</h3> IMPROVED is multicenter trial 479 patients (symptoms <2 years) rheumatoid arthritis (RA 2010 criteria) 131 undifferentiated (UA) baseline Disease Activity Score (DAS) ≥1.6. All started MTX 25mg/wk...
<h3>Background</h3> Physical activity (PA) according to public health guidelines is effective and safe for people with rheumatic musculoskeletal diseases, including axial spondyloarthritis (axSpA), should be promoted by healthcare providers.<sup>1</sup> In axSpA, in particular high intensity aerobic PA beneficial, yet this was found incompletely implemented physical therapy programs.<sup>2</sup> Studies describing axSpA patients without are lacking. <h3>Objectives</h3> To describe the...