A5014381494- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Pulmonary Hypertension Research and Treatments
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Bacterial Genetics and Biotechnology
- Cardiac Imaging and Diagnostics
- Tracheal and airway disorders
- Aortic Disease and Treatment Approaches
- Congenital Diaphragmatic Hernia Studies
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Ultrasound in Clinical Applications
- Enzyme Structure and Function
- Protein Structure and Dynamics
Nemours Children's Health System
2024
Children's Hospital of Philadelphia
2017-2021
Icahn School of Medicine at Mount Sinai
2019-2020
University of Pennsylvania
2017-2018
Emory University
2016-2017
Baylor College of Medicine
2017
Cincinnati Children's Hospital Medical Center
2017
Hauptman-Woodward Medical Research Institute
2009
Background— Outcomes after right ventricle (RV) decompression in infants with pulmonary atresia intact ventricular septum vary widely. Descriptions of outcomes are limited to small single-center studies. Methods and Results— Neonates undergoing RV for were included from 4 pediatric centers. Primary end point was reintervention post-RV decompression; secondary points circulation type at latest follow-up. Ninety-nine patients (71 28 virtual atresia) underwent median 3 (25th–75th, 2–5) days...
Abstract Background Transcatheter right ventricle decompression in neonates with pulmonary atresia and intact ventricular septum is technically challenging, risk of cardiac perforation death. Further, despite successful decompression, re-intervention on the valve common. The association between technical factors during risks complications are not well described. Methods This a multicentre retrospective study among participating centres Congenital Catheterization Research Collaborative....
Elucidating the structures of membrane proteins is essential to our understanding disease states and a critical component in rational design drugs. Structural characterization protein begins with its detergent solubilization from lipid bilayer purification within functionally stable protein-detergent complex (PDC). Crystallization PDC typically occurs by changing solution environment decrease solubility promote interactions between exposed hydrophilic surface residues. As have been observed...