This paper presents experimental heat transfer results in a two-pass square channel with smooth and ribbed surfaces. The ribs are placed staggered half-V fashion the rotation orthogonal to axis. orientation varies respect plane. A change about rotating frame causes secondary flow structure associated turbulence distribution. Consequently, coefficient from individual surfaces of changes. effects number on local Nusselt ratio distributions presented. Heat coefficients show different...

Six tritium-labeled cardiac glycosides (ouabain, dihydro-ouabain, digoxin, digitoxin, convallatoxol and pro-scillaridin, each in a concentration of 10-7M) were perfused through guinea-pig hearts for 64 min, followed by 8 min washout. The resultant uptake the varied more than 100-fold, dihydro-ouabain showing lowest tissue content proscillaridin highest. In heart homogenates, marked differences found supernatant/pellet ratio with various glycosides. Upon fractionation, all instances highest...

Guinea-pig and rat hearts were perfused via the aorta at constant flow with 10-7 M digoxin-H3 for periods up to 64 min. The temperature was 28°C. then 8 min nonradioactive medium whole tissue subcellular fraction digoxin contents measured. arteriovenous difference in this system zero after 2 4 of perfusion. heart content, however, continued rise throughout perfusion, particularly during period from 32 concentration also rose nuclear, mitochondrial microsomal fractions time, fastest greatest...

Ouabain-H 3 was administered intravenously to a number of human subjects. Ouabain disappeared from plasma at rate which suggested processes with half-lives approximately minutes and 5 hours. excreted primarily in urine, biliary excretion being much less importance. Ousbain unchanged form—evidence for the presence ouabain metabolites not obtained. Coronary arteriovenous difference ouabain-H3 present only first4 following administration. A period extracorporeal circulation did regularly...

Guinea-pig hearts were perfused at constant flow via the aorta with ouabain-H8 in concentrations ranging from 1 X 10-6 M to M. Perfusion was continued for 64 minutes and followed by eight of washout. The cardiac uptake showed indications saturability this system. concentration ouabain microsomal fraction greater than heart as a whole, whereas other particulate fractions lei that whole. guinea-pig directly related sodium ions perfusing medium inversely potassium extracellular medium. ionic...

Film-cooling technology is used in high-temperature components of gas turbines to extend their service lives. Hot-gas path are susceptible damage or failure the absence film cooling. Much optimization research efforts have been focused on hole shapes, heat/mass transfer measurement techniques, and cooling performance under various mainstream coolant side operating conditions. Due recent rapid advancements areas techniques (e.g., pressure-sensitive paints fast high-resolution imaging) metal...

The ability of the nonlinear k–ε turbulence model to predict flow in a separated duct past wall-mounted, two-dimensional rib was assessed through comparisons with standard and experimental results. Improved predictions streamwise intensity mean velocities near high-speed edge shear layer downstream reattachment were obtained model. More realistic production dissipation turbulent kinetic energy also obtained. Otherwise, performance two models comparable, both performing quite well core...

Impingement heat transfer is considered one of the most effective cooling technologies that yield high localized convective coefficients. This paper studies different configurable parameters involved in jet impingement such as, exit orifice shape, crossflow regulation, target surface modification, spent air reuse, channel pulsation, and other techniques to understand which them are critical how these heat-transfer-enhancement concepts work. The aim this excite thermal sciences community...

The effects of six glycosides (ouabain, dihydro-ouabain, digitoxin, digoxin, proscillaridin and convallatoxol) on ventricular transmembrane potential contractile charcteristics were studied in order to compare their mode action. It has been generally assumed that all induce similar cardiac muscle, although potentials show wide variations. potencies most the approximately same, with dthydro-ouabain having about 1/30 others. dose-response curves digitoxin ouabain also equal. was found these...

Ouabain was catalytically tritiated using platinum oxide catalyst. The products of the reaction included ouabain-H3 and dihydro-ouabain-H3. two glycosides were separated chromato-graphically identified by color tests, chromatographic behavior infrared spectro-photometry. The route excretion ouabain dihydro-ouabain shows marked species differences. In rat, these drugs are preferentially eliminated in bile, while sheep they urine. appears to be more rapidly than both species. Studies...

Abstract The ground state of a rotating Bose-Einstein condensate trapped in two-dimensional anharmonic–anisotropic potential is analyzed numerically at the limit an infinite number particles. We find that density breaks up along x direction position space and p y momentum together with acquisition angular momentum. Side by side, anisotropies many-particle variances directions become opposite when computed many-body mean-field levels theory. All all, bosons are found to possess unique...

This paper focuses on turbine blade internal cooling. Internal cooling is achieved by passing the coolant through several rib-enhanced serpentine passages inside and extracting heat from outside of blades. Both jet impingement pin-fin-cooling are also used as a method In past number years there has been considerable progress in research this limited to reviewing few selected publications reflect recent developments

Summary Diphenylhydantoin (DPH) and potassium significantly prevent ouabain intoxication without preventing the inotropic effects of in guinea‐pig isolated heart. The antiarrhythmic effect DPH K on ouabain‐induced toxicity appears to be related their ability reduce accumulation by myocardium thereby intracellular Na changes which lead arrhythmic state.

1. The ability of isolated perfused guinea-pig (digitalis-sensitive species) and rat (digitalis-resistant hearts to accumulate radio-labelled digitalis glycosides was studied in relation the ionic composition perfusion medium.2. It observed that both species much less digoxin accumulated than digitoxin or proscillaridin.3. accumulation markedly inhibited a low sodium high potassium medium. These effects were similar, but relatively marked, with proscillaridin. Calcium magnesium removal had...