- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Respiratory Support and Mechanisms
- Innovation and Knowledge Management
- Respiratory and Cough-Related Research
- Entrepreneurship Studies and Influences
- Smoking Behavior and Cessation
- Innovation Policy and R&D
- Health and Lifestyle Studies
- Firm Innovation and Growth
- Energy, Environment, Economic Growth
- Supply Chain Resilience and Risk Management
- Chronic Disease Management Strategies
- Nasal Surgery and Airway Studies
- Innovative Teaching Methods
- Biomedical and Engineering Education
- Delphi Technique in Research
- Engineering Education and Curriculum Development
- Medical research and treatments
- Injury Epidemiology and Prevention
- COVID-19 Pandemic Impacts
- International Business and FDI
- University-Industry-Government Innovation Models
- School Health and Nursing Education
- Obstructive Sleep Apnea Research
Pontificia Universidad Católica de Chile
2013-2024
Massachusetts Institute of Technology
2009-2020
Hospital Clínico Universitario de Caracas
2012
Central University of Venezuela
2012
Hospital Clínico de la Universidad Católica
1997
Hammersmith Hospital
1990-1991
London Postgraduate Medical and Dental Education
1988
The aim of the present study was to evaluate association between history tuberculosis and airflow obstruction. A population-based, multicentre carried out included 5,571 subjects aged ≥40 yrs living in one five Latin American metropolitan areas: Sao Paulo (Brazil); Montevideo (Uruguay); Mexico City (Mexico); Santiago (Chile); Caracas (Venezuela). Subjects performed pre- post-bronchodilator spirometry were asked whether they had ever been diagnosed with by a physician. overall prevalence...
Little information exists regarding the epidemiology of chronic bronchitis phenotype in unselected obstructive pulmonary disease (COPD) populations. We examined prevalence COPD and non-COPD subjects from PLATINO study, investigated how it is associated with important outcomes. Post-bronchodilator forced expiratory volume 1 s/forced vital capacity <0.70 was used to define COPD. Chronic defined as phlegm on most days, at least 3 months per year for ≥2 yrs. also analysed another definition:...
There is evidence to suggest sex differences exists in chronic obstructive pulmonary disease (COPD) clinical expression. We investigated health status perception, dyspnoea and physical activity, factors that explain these using an epidemiological sample of subjects with without COPD. PLATINO a cross-sectional, population-based study. defined COPD as post-bronchodilator forced expiratory volume 1 s/forced vital capacity ratio <0.70, evaluated perception (Short Form (SF)-12 questionnaire)...
The effect of inspiratory muscle training (IMT) on exercise capacity in patients with chronic airflow limitation (CAL) has been debated. present study was planned to further investigate the effects IMT performance. Twenty (aged 62+/-1 yrs; forced expiratory volume one second/forced vital (FEV1/FVC) 36+/-2%) were trained 30 min daily for 6 days a week during 10 weeks, either 30% (Group 1) or 10% 2) peak maximal pressure (PI,max) as load. Exercise performance evaluated by distance walked...
Pulmonary function has been extensively studied in unilateral diaphragmatic paralysis (UDP), but there is scarce information regarding inspiratory muscle this condition. We therefore 8 patients with UDP (Group 1: age 48.3 +/- 2.1 yr of age, means SD) as well 7 and concomitant cardiopulmonary disease 2: 60.6 13 age). Twelve young normal subjects were also (32.3 7.7 Maximal static transdiaphragmatic mouth pressure measured at FRC. Gastric (Pga), esophageal (Pes), (Pdi) swings during quiet...
The aim of this study was to describe the impact using bronchodilators on prevalence Chronic Obstructive Pulmonary Disease in a population-based survey (Platino study). A cluster sampling subjects 40 years age or older, representative metropolitan areas 5 Latin American cities (Sao Paulo, Mexico, Montevideo, Santiago and Caracas) chosen. Spirometry according ATS standards done before after inhalation 200 micrograms salbutamol 5183 subjects. Prevalences airflow obstruction were estimated...
The PLATINO project was launched in 2002 order to study the prevalence of chronic obstructive pulmonary disease (COPD) Latin America. Because smoking is main risk factor for COPD, detailed data on it were obtained. aim this paper evaluate and incidence initiation among middle-aged older adults (40 years or older). Special emphasis given association between schooling.PLATINO a multicenter comprising five cross-sectional population-based surveys approximately 1,000 individuals per site Sao...
Purpose This study explores the structure of founders’ hybrid personal identities and their relationship to social venture performance. The authors hypothesize that founders experience tension between commercial goals as a paradox rooted in values. Design/methodology/approach surveyed 112 enterprise Chile used structural equation modeling test hypotheses about self-transcendent values (i.e. promotion others’ welfare care for nature) self-enhancement pursuing own interests power over others)...