A5076200839- Pancreatic and Hepatic Oncology Research
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Hepatocellular Carcinoma Treatment and Prognosis
- Surgical Simulation and Training
- Pancreatitis Pathology and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Cytokine Signaling Pathways and Interactions
- Colorectal Cancer Surgical Treatments
- Aortic aneurysm repair treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Inflammatory Biomarkers in Disease Prognosis
- Anatomy and Medical Technology
- Ultrasound and Hyperthermia Applications
- Cancer Genomics and Diagnostics
- Renal cell carcinoma treatment
- Congenital Anomalies and Fetal Surgery
- Gastrointestinal Tumor Research and Treatment
- Neuroendocrine Tumor Research Advances
- Inflammasome and immune disorders
- Advances in Oncology and Radiotherapy
- Infectious Aortic and Vascular Conditions
- COVID-19 and healthcare impacts
Institutul Regional de Gastroenterologie Prof. Dr. Octavian Fodor
2015-2025
Iuliu Hațieganu University of Medicine and Pharmacy
2021-2025
Technical University of Cluj-Napoca
2024
Clinical Emergency Hospital Bucharest
2015-2024
Yahoo (United Kingdom)
2023
Radboud University Medical Center
2019
Sint Maartenskliniek
2018-2019
Radboud University Nijmegen
2019
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca
2019
University College London
2006
To assess safety and efficacy of repeated B-cell depletion with rituximab in patients rheumatoid arthritis (RA).Thirty-seven refractory RA entered into a programme B-lymphocyte (up to 5 cycles, 89 cycles total) protocols based on the anti-CD20 monoclonal antibody, rituximab, have been observed over periods >5 yrs (n = 22) or 3-5 14).Twenty two subjects followed up for yrs. Average duration benefit per cycle was 15 months (maximum 43 months), time re-treatment 20 months. Nineteen remain...
Background: Oncological surgery during the COVID-19 pandemic was performed only in carefully selected cases, due to variation allocation of resources. The purpose this study highlight impact lockdown on presentation, diagnosis, and surgical management colorectal cancers as well post-pandemic changes area. Material methods: This single center, retrospective comparative contained 1687 patients, divided into three groups with equal time frames two years, consisting a pre-pandemic, pandemic,...
The pathogenesis of chronic joint inflammation remains unclear, although the involvement pathogen recognition receptors has been suggested recently. In present article, we describe role two members NACHT-LRR (NLR) family, Nod1 (nucleotide-binding oligomerization domain) and Nod2 in a model acute induced by intraarticular injection Streptococcus pyogenes cell wall fragments. Here, show that deficiency resulted reduced protection against early cartilage damage. contrast, gene-deficient mice...
The status of predictive biomarkers in metastatic colorectal cancer is currently underdeveloped. Our study aimed to investigate the value six circulating exosomal miRNAs derived from plasma (miR-92a-3p, miR-143-3p, miR-146a-5p, miR-221-3p, miR-484, and miR-486-5p) for chemosensitivity, resistance patterns, survival. Thirty-one patients were selected before receiving first-line irinotecan- or oxaliplatin-based chemotherapy. Blood samples harvested at baseline 4-6 months after initiation...
Pancreatic cancer is an aggressive malignancy, surgery being the only potentially curative treatment. The systemic inflammatory response important factor in development of cancer. There still controversy regarding its role pancreatic cancer.Our study a retrospective observational cohort study. We included patients diagnosed with ductal adenocarcinoma (PDAC), who underwent surgical resection our hospital, between January 2012 and December 2019. gathered information from preoperative...
Hydatid liver disease remains an important issue in endemic areas, which may require immediate surgery. Although laparoscopic surgery is on the rise, presence of certain complications conversion to open approach.To compare results treatment and approach context a 12-year single institution experience, perform further comparison between from current study those previous study.Between January 2009 December 2020, 247 patients underwent for hydatic our department. Of patients, 70 treatment. A...
Background: En bloc removal of the kidney with tumor thrombus excision in a multidisciplinary team remains standard treatment for renal cell carcinoma (RCC) extension. In order to minimize hemodynamic impact surgical blood loss, intraoperative salvage (IOCS) techniques can decrease need allogeneic and prevent transfusion related complications. Objective: this article, we evaluated safety IOCS during radical nephrectomy inferior vena cava thrombectomy under cardiopulmonary bypass or without...
Introduction: Image-guided invasive procedures on the liver require a steep learning curve to acquire necessary skills. The best and safest way achieve these skills is through hands-on courses that include simulations phantoms of different complications, without any risks for patients. There are many market made various materials; however, there few multimodal phantoms, only two cast in 3D-printed mold. Methods: We created virtual mold by segmenting CT scan. InVesalius Autodesk Fusion 360...
Surgical treatment of toracoabdominal aortic aneurysms (TAAA) represents a difficult problem for the vascular surgeon and may become formidable challenge in an emergency procedure. In patient with hemodynamic instability, protective measures as cerebral spinal fluid drainage bio-pump against cord, visceral renal ischemia, be ineffective or impracticable.We report our experience 51 emergency-operated patients TAAA out 660 treated between 1994 2014; 48 (94%) were hemodynamically unstable, 3...