Lauren T. Callaghan

ORCID: 0000-0002-3662-8620
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About
Contact & Profiles
Research Areas
  • Pleural and Pulmonary Diseases
  • Inflammasome and immune disorders
  • RNA and protein synthesis mechanisms
  • Antimicrobial Resistance in Staphylococcus
  • Infections and bacterial resistance
  • Gun Ownership and Violence Research
  • Diversity and Career in Medicine
  • Antimicrobial Peptides and Activities
  • Streptococcal Infections and Treatments
  • Medical Education and Admissions
  • Foreign Body Medical Cases
  • Intimate Partner and Family Violence
  • Innovations in Medical Education
  • Pneumothorax, Barotrauma, Emphysema
  • Homicide, Infanticide, and Child Abuse

Baylor College of Medicine
2023-2024

The University of Texas Southwestern Medical Center
2022

Texas Christian University
2019

Type 3 Secretion System (T3SS) is a highly conserved virulence structure that plays an essential role in the pathogenesis of many Gram-negative pathogenic bacteria, including Pseudomonas aeruginosa. Exotoxin T (ExoT) only T3SS effector protein expressed all T3SS-expressing P. aeruginosa strains. Here we show recognition leads to rapid phosphorylation cascade involving Abl / PKCδ NLRC4, which results NLRC4 inflammasome activation, culminating inflammatory responses limit infection wounds. We...

10.1038/s41467-022-28967-5 article EN cc-by Nature Communications 2022-03-11

Staphylococcus aureus is a leading cause of infection in the United States, and due to rapid development resistance, new antibiotics are constantly needed. trans -Translation particularly promising antibiotic target because it conserved many bacterial species, critical for survival, unique among prokaryotes.

10.1128/aac.02362-18 article EN Antimicrobial Agents and Chemotherapy 2019-01-25

Abstract Objectives The emergency medicine (EM) physician workforce is largely composed of white men. Despite recruitment efforts over the past decade, there has not been a significant increase trainees with underrepresented racial and ethnic identities in EM (URM). Prior studies have focused on institutional strategies to improve diversity, equity, inclusion (DEI) residency but limited describing URM trainees’ perspectives. We sought assess perspectives DEI application selection process....

10.1002/aet2.10888 article EN AEM Education and Training 2023-06-01

To characterize the sociological risk factors for firearm intimate partner violence (IPV) among women in Texas, with a focus on lethal predictors to aid screening and intervention guidelines.

10.1089/jwh.2024.0279 article EN Journal of Women s Health 2024-09-04

Abstract Esophagopericardial fistulas are an extremely rare structural defect that may arise from malignant or iatrogenic etiologies. This article reports the case of a patient with cardiac tamponade secondary to hydropneumopericardium esophagopericardial fistula. Given high morbidity and mortality this condition, describes challenges in diagnosis clinical decision-making improve early identification interdisciplinary management.

10.14503/thij-24-8443 article EN cc-by-nc Texas Heart Institute Journal 2024-01-01
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