Shambel Wedajo

ORCID: 0000-0002-3679-301X
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Research Areas
  • HIV/AIDS Research and Interventions
  • HIV/AIDS drug development and treatment
  • HIV Research and Treatment
  • Child Nutrition and Water Access
  • Global Maternal and Child Health
  • Adolescent Sexual and Reproductive Health
  • Infant Nutrition and Health
  • Pneumocystis jirovecii pneumonia detection and treatment
  • HIV, Drug Use, Sexual Risk
  • Food Security and Health in Diverse Populations
  • Breastfeeding Practices and Influences
  • Hepatitis C virus research
  • Cardiac Health and Mental Health
  • Heart Rate Variability and Autonomic Control
  • Neonatal Respiratory Health Research
  • Neonatal and Maternal Infections
  • Blood Pressure and Hypertension Studies
  • Energy and Environment Impacts
  • Medication Adherence and Compliance
  • Tuberculosis Research and Epidemiology
  • HIV/AIDS Impact and Responses
  • Air Quality and Health Impacts
  • Child Nutrition and Feeding Issues

Wollo University
2020-2024

Bahir Dar University
2022

Abstract Introduction Uncontrolled blood pressure contributes a huge contribution to many hypertension-related complications and it is one of the unbeaten problems for patients taking antihypertensive drugs. The association social support other factors with uncontrolled during covid-19 pandemic not well investigated. Therefore, this study explored determinants control status COVID-19 among hypertension who were on an treatment. Method A cross-sectional was done from March May 2021 adults...

10.1186/s12889-022-13368-6 article EN cc-by BMC Public Health 2022-05-09

This analysis is to present the burden and trends of morbidity mortality due lower respiratory infections (LRIs), their contributing risk factors, disparity across administrative regions cities from 1990 2019.This used Global Burden Disease 2019 framework estimate outcomes LRI its factors. The study uses all available data sources Cause Death Ensemble model deaths a meta-regression disease modelling technique non-fatal with 95% uncertainty intervals (UI).The includes nine region states two...

10.1136/bmjopen-2022-068498 article EN cc-by BMJ Open 2023-09-01

Depression has a multitude of clinical and public health consequences for HIV patients. The magnitude patients who failed first-line antiretroviral treatment switched to second-line therapy is becoming growing concern. However, unlike therapy, date, little attention been given mental problems in such patients, particularly the era COVID-19 pandemic. Thus, this research was conducted determine depression its determinants among on therapy.A multi-centered cross-sectional study 714 were...

10.1186/s13033-022-00536-9 article EN cc-by International Journal of Mental Health Systems 2022-06-13

Even though there are many patients on second-line antiretroviral therapy (ART) in Ethiopia, is a paucity of evidence the rate viral resuppression and its predictors. Therefore, this study aimed to determine time identify predictors among adults ART South Wollo public hospitals, northeast Ethiopia.A retrospective-cohort design was employed using enrolled from August 28, 2016 April 10, 2021. Data were collected structured data-extraction checklist with sample size 364 February 16 March 30,...

10.2147/hiv.s406372 article EN cc-by-nc HIV/AIDS - Research and Palliative Care 2023-07-01

Abstract Background Composite Index of Anthropometric Failure (CIAF) combines all three forms anthropometric failures to assess undernutrition status children. There is no study on CIAF identify the real and severe form under nutrition among Ethiopian children that addressed community level factors. So, this determined identified important factors which helps design appropriate intervention strategies by using multi-level advanced statistical model. Methods The included 5,530 five utilized a...

10.1186/s12889-024-18625-4 article EN cc-by BMC Public Health 2024-04-24

The persistent efforts of HIV/AIDS epidemiology remain one the world's most important community health threats. To avoid becoming an epidemic, UNAIDS has set three 90% fast-track targets for 2020, and Ethiopia also changed its implementation since 2015. However, achievement in Amhara region have yet to be evaluated at end programme period.The aim this study was assess Trends HIV Infection Antiretroviral Treatment outcome Eastern Regional from 2015 2021, Northeast Ethiopia.A retrospective...

10.2147/hiv.s411235 article EN cc-by-nc HIV/AIDS - Research and Palliative Care 2023-07-01

Tuberculosis (TB) is major public health concern and Isoniazid Preventive Therapy (IPT) helps to prevent TB development among patients living with human immune deficiency virus (PLWHIV). However, the evidence limited especially in study area. Therefore, this aimed determine prevalence factors associated IPT users non-IPT of PLWHIV Dessie, Ethiopia. A comparative cross-sectional was employed for1 month Dessie. total 326 respondents were selected using systematic random sampling. Bivariable...

10.1038/s41598-022-16437-3 article EN cc-by Scientific Reports 2022-08-05

Background The proportion of HIV patients on second-line antiretroviral therapy is becoming a growing public health concern, especially in low-income country setting. However, unlike first-line therapy, to date, very little known about the outcomes Ethiopia context. Thus, this study was conducted determine rate treatment failure, death, and their predictors among receiving therapy. Methods A retrospective cohort 642 people living with Dessie Comprehensive Specialized Hospital from October...

10.1371/journal.pone.0269235 article EN cc-by PLoS ONE 2022-06-01

Background: Virological failure is defined as having viral load measurement greater or equal to 1000 copies/mm 3 after at least six-month exposure antiretroviral therapy. According the Joint United Nations Programme on HIV/AIDS (UNAIDS-2018) report, globally nearly one in five patients first-line therapy had experienced virological failure. In line with this, Ethiopia federal ministry of health also reported that four year 2016. To date, very little known about predictors local context....

10.2147/hiv.s267629 article EN cc-by-nc HIV/AIDS - Research and Palliative Care 2020-11-01

In Ethiopia, first-line antiretroviral therapy failure is growing rapidly. However, unlike therapy, to date, very little known about the outcomes of second-line therapy. Thus, this study assessed rate viral re-suppression and attrition care their predictors among people living with HIV on therapy.A retrospective cohort was conducted 642 at Dessie Comprehensive Specialized Hospital from October 2016 November 2019. A proportional Cox regression model computed explore (viral load less than 1000...

10.2147/hiv.s323445 article EN cc-by-nc HIV/AIDS - Research and Palliative Care 2021-09-01

Abstract Background Medication adherence plays a pivotal role in achieving the desired treatment outcomes. The proportion of HIV patients on second-line antiretroviral therapy is becoming growing public health concern. However, to date, little attention has been given medication adherence. Moreover, association between facility characteristics and yet not tested. Thus, this research was conducted determine magnitude examine facility-level determinants among ART. Methods A cross-sectional...

10.1186/s12981-022-00441-8 article EN cc-by AIDS Research and Therapy 2022-03-26

Background: Neonates are commonly admitted to neonatal intensive care units, and the type(s) of admission determine outcome neonate. Therefore, we sought assess magnitude associated factors at selected hospitals in Wollo, northeast Ethiopia 2022. Methods: A cross-sectional study on 422 mother–neonate pairs was conducted. Data were collected by face-to-face interviews reviewing patient records then entered analyzed using EpiData version 3.1 Stata 14, respectively. Binary logistic regression...

10.2147/rrn.s418964 article EN cc-by-nc Research and Reports in Neonatology 2023-11-01

Abstract Background Birth weight remains as one of the facing factors and leading causes child suffering worldwide. This is a major problem especially in low middle income countries most importantly vulnerable populations like refugee. However, there limited evident yet study area. Objective The aim this was to assess birth associated among host refugee neonates at health facilities Gambella Region. Methods A facility based comparative cross-sectional applied settings. total five hundred...

10.1101/2022.06.27.22276951 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2022-06-27

Abstract Background Birth weight remains as one of the facing factors and leading causes child suffering worldwide. This is a major problem especially in low middle income countries most importantly vulnerable populations like refugee. However, there limited evident yet study area. Objective The aim this was to assess birth associated among host refugee neonates at health facilities Gambella Region. Methods A facility based comparative cross-sectional applied settings. total five hundred...

10.21203/rs.3.rs-1790323/v1 preprint EN cc-by Research Square (Research Square) 2022-07-22

Abstract Background: In Ethiopia, first line antiretroviral therapy failure is growing rapidly. However, unlike therapy, to date, very little known about the outcomes of second therapy. Thus, this study assessed rate viral re-suppression and retention care their predictors among HIV infected patients on Methods: A retrospective cohort was conducted 642 at Dessie Comprehensive Specialized Hospital, northeast Ethiopia from October 2016 November 2019. Proportional Cox regression model computed...

10.21203/rs.3.rs-193273/v1 preprint EN cc-by Research Square (Research Square) 2021-02-16
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