A5057268701- Stress Responses and Cortisol
- Adipose Tissue and Metabolism
- Tryptophan and brain disorders
- Circadian rhythm and melatonin
- Heart Rate Variability and Autonomic Control
- Apelin-related biomedical research
- Pharmacological Effects and Toxicity Studies
- Erythropoietin and Anemia Treatment
- Thyroid Disorders and Treatments
- Anesthesia and Sedative Agents
- Pharmacology and Obesity Treatment
- Optimism, Hope, and Well-being
- 3D Printing in Biomedical Research
- Coordination Chemistry and Organometallics
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pharmacological Receptor Mechanisms and Effects
- Liver Disease Diagnosis and Treatment
- Exercise and Physiological Responses
- Genetics and Neurodevelopmental Disorders
- Cardiac Arrest and Resuscitation
- Botulinum Toxin and Related Neurological Disorders
- Regulation of Appetite and Obesity
- Cultural and Sociopolitical Studies
- Mindfulness and Compassion Interventions
- Digital Storytelling and Education
Balıkesir University
2019-2025
Ankara University
2016-2021
Epoetin alfa is a derivative of the erythropoietin hormone. This study aims to investigate epoetin effect on anxiety-like behaviors. Adult female Wistar Albino rats were divided into Control (n = 8), 1000 U Epoetien alfa, and 2000 alpha. was administered intraperitoneally once week for 4 weeks. The animals then subjected open field test, elevated plus maze, light-dark box, behaviors video recorded. significantly reduced in both low- high-dose groups dose-independent manner. anxiolytic seen...
We aimed to investigate the anxiolytic effect of darbepoetin alpha (DEPO), an erythropoietin derivative, in a neuroinflammation model regarding different behaviors and biological pathways.
Diabetes is a metabolic disorder characterized by hyperglycemia and impaired insulin secretion or action.Psychological comorbidities, such as depression anxiety, are more common in people with diabetes.Exercise results anxiolytic effects, demonstrated numerous studies.This study aims to evaluate potential effects of aerobic exercise streptozotocin (STZ)-induced diabetes.Male Wistar albino rats (n=40) were randomly divided into four groups control, exercise, diabetes, diabetes +...
We aimed to examine the level of hippocampal neurogenesis, and assess learning anxiety some proteins involving insulin signaling pathways in rats with Metabolic Syndrome (MetS); reveal relationship among them.Totally, 30 Wistar-albino were used. The divided into three groups: Control, MetS, MetS+Ins. Immunohistochemical staining was performed evaluate levels neurogenesis markers; Doublecortin (DCX), Neuronal-Differentiation-1 (NeuroD1), Ki67, Neuronal nuclear protein (NeuN). Then, cleaved...
New Findings What is the central question of this study? We evaluated effects diabetes and exercise on lipopolysaccharide‐induced acute lung injury. By providing a comprehensive analysis redox status, blood gases histological parameters, we aimed to contribute ongoing debate in literature. are main findings its importance? demonstrated preventive effect exercise, but did not alter severity Abstract Acute injury (ALI) life‐threatening respiratory condition. Diabetes (DM) metabolic disease...
Stress, which triggers many physiological and behavioral responses in the organism, is an important risk factor that plays a role origin of psychiatric disorders such as depression anxiety. This study aimed to investigate inflammation, oxidative stress status, anxiety, depression-like behaviors adolescent rodents exposed chronic intermittent cold stress. Adolescent male rats were subjected modified model (21 days, 1 hour day, 4°C). Depression-like evaluated sucrose preference forced swimming...
Pregabalin is an antiepileptic drug that binds to the alpha-2/delta unit at presynaptic voltage-dependent calcium channels. We aimed investigate effect of acute and chronic pregabalin administration on anxiety depression-like behaviors.
Öz
Background: Ketamine is a widely used anesthetic agent. Although the potential adverse effects of ketamine use in juvenile age are uncertain, certain studies reported that children exposed to recurrent anesthesia could face an increased risk neurodevelopmental deficits motor function and behavioral risks. We aimed investigate long-term repeated exposure various doses on anxious behavior locomotor activity rats. background: Objective: objective: Methods: Thirty-two Wistar Albino male rats...
Hypothyroidism is one of the common diseases worldwide that occurs when thyroid gland unable to produce enough hormone for body's metabolic needs. Thyroid hormones play a critical role in activity brain, and hypothyroidism has important effects on neuropsychiatric function. The incidence depressive syndrome higher patients with hypothyroidism. However, mechanism depression other psychiatric disorders caused by stil unclear. symptomatic manifestations are diverse it possible model many them...
Giriş: Kronik stres maruziyeti homeostaz durumunu bozmakta ve immun değişikliklere yol açmaktadır. Eritrosit dağılım genişliği nötrofil lenfosit oranı, sistemik inflamasyonu değerlendirmede kullanılabilmektedir. Bu çalışmada kronik modelinin, adolesan dönem sıçanlarda hematolojik parametreleri nasıl etkilediği incelenmiştir. Yöntemler: 16 adet Wistar albino erkek sıçan, kontrol grubu olarak iki gruba ayrılmıştır. Stres grubuna modifiye edilmiş aralıklı soğuk modeli 28 gün boyunca...
Purpose: Although being physically active may not seem more important to medical students than their classes, physical activity is for human health. As seen in different methodological studies, affects cognitive functions. Few of these studies are related youth. Therefore, we aimed analyze and parameters association between each other cross sectional study.
 Materials Methods:138 from all classes a faculty were included the study. Medical completed three scales. Physical was determined...