A5004973143- Laser-Ablation Synthesis of Nanoparticles
- Laser-induced spectroscopy and plasma
- Electrohydrodynamics and Fluid Dynamics
- Analytical chemistry methods development
- Laser Material Processing Techniques
- Ocular and Laser Science Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Surface Polishing Techniques
- Laser-Matter Interactions and Applications
- Industrial Gas Emission Control
- Chemical Thermodynamics and Molecular Structure
- Biodiesel Production and Applications
- Cyclone Separators and Fluid Dynamics
- Laser Design and Applications
- Laser-Plasma Interactions and Diagnostics
- Surface Roughness and Optical Measurements
University of Szeged
2019-2024
Abstract We studied the application of pulsed laser ablation (PLA) for particle size reduction in non-steroidal anti-inflammatory drugs (NSAIDs). Grinding poorly water-soluble NSAID crystallites can considerably increase their solubility and bioavailability, thereby necessary doses be reduced significantly. used tablets ibuprofen, niflumic acid meloxicam as targets. Nanosecond pulses were applied at various wavelengths (KrF excimer laser, λ = 248 nm, FWHM 18 ns Nd:YAG 1 532 nm/λ 2 1064 6 ns)...
Recently, the number of water insoluble and poorly soluble drug compounds has increased significantly. Therefore, growing interest been witnessed in different particle size reduction techniques to improve dissolution rates, transport characteristics bioavailability drugs. Laser ablation proven be an alternative method production nano- micrometre-sized particles without considerable chemical damage. We present nanosecond laser pastilles distilled water, targeting meloxicam, a nonsteroidal...
Abstract We investigated the application of pulsed laser ablation (PLA) for production magnetic nanoparticles (MNPs)/drug nanocomposites. Magnetic drug delivery vehicles can provide a multifunctional theranostic platform and allow combination diagnostics, monitoring therapeutics. applied nanosecond pulses at two different wavelengths (Nd:YAG laser, λ 1 = 532 nm/ 2 1064 nm, FWHM 6 ns) target tablets consisting mixture ibuprofen (as model drug) magnetite NPs in various mass ratios....
In this paper, improved operation of a high-contrast, high-brightness ultraviolet laser system is described. The based on conventional short-pulse dye/excimer design, modified to contain 3 KrF excimer amplifiers and the recently developed nonlinear Fourier-filtering stage for contrast improvement. final amplifier accepts beam size ~4x4 cm2, producing 100 mJ energy short-pulses using two-beam interferometric multiplexing setup. Temporal measurements output showed positively chirped pulses...
Abstract Ablation with ultrashort laser pulses as a surface micromachining tool was studied using hybrid die-excimer system that has high energy per pulse (tens of mJ’s), about 600 fs duration and low repetition rate (2 Hz). The effect ablation on the material microstructure this pulsed studied. Micropillars were fabricated by spot size hundreds micrometers. Two methods tested for micromachining. Multiple standing sample resulted in columnar microscturcure around micropillars. This unwanted...