- Moyamoya disease diagnosis and treatment
- Aortic Disease and Treatment Approaches
- Cerebrovascular and genetic disorders
Beijing Tian Tan Hospital
2022
Capital Medical University
2022
Peking University
2022
Peking University International Hospital
2022
The association of DNA methylation with the pathogenesis adult ischemic moyamoya disease (MMD) is unknown. Here, we investigated genome-wide profiles in patients MMD and identified genes related to MMD. Whole blood samples were collected from 20 individuals, including 10 without any underlying healthy individuals. Genome-wide analysis was performed using Illumina 850K microarrays. Transcriptional correlation verified quantitative reverse transcription-polymerase chain reaction. In vitro...