- Musculoskeletal pain and rehabilitation
- Therapeutic Uses of Natural Elements
- Meta-analysis and systematic reviews
- Medical and Biological Ozone Research
- Vascular Malformations and Hemangiomas
- Occupational Health and Burnout
- Health and Medical Studies
- Hemodynamic Monitoring and Therapy
- Salivary Gland Tumors Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Autoimmune and Inflammatory Disorders Research
- Cutaneous Melanoma Detection and Management
- Non-Invasive Vital Sign Monitoring
- Delphi Technique in Research
- Occupational health in dentistry
- Nonmelanoma Skin Cancer Studies
- Complementary and Alternative Medicine Studies
- Health Systems, Economic Evaluations, Quality of Life
- Global Health Care Issues
- Mechanical Circulatory Support Devices
- Orthopedic Infections and Treatments
- Health Education and Validation
- Youth, Drugs, and Violence
Centro Hospitalar Tondela-Viseu
2024
Universidade Tiradentes
2017-2020
The systematic review of randomized clinical trials is crucial to assess the safety and effectiveness intermediate procedures. objective this article present a tutorial for planning execution meta-analysis trial studies. literature type research that organizes, criticizes, integrates available evidence published in health field. Systematization leads less bias, however, quality reviews may not always be perceived due way it described articles. information disclosed articles free bias. steps...
<h3>Background:</h3> Patients with spondyloarthritis (SpA) using tumor necrosis factor inhibitors (TNFi) can have an inadequate response, discontinuation rates of up to 50-60% in two years [1]. For several years, TNFis were the only biologic disease-modifying anti-rheumatic drugs (bDMARDs) available for SpA and introduction IL-17 (IL-17i) changed treatment paradigm [2]. Switching another mechanism action (MOA) or cycling TNFi after failure first (1<sup>st</sup>) is still a debatable topic....
Objetivo: O objetivo do presente estudo foi apresentar um tutorial para planejamento e execução de ensaios clínicos randomizados. Materiais métodos: Uma busca realizada na base dados digital MEDLINE via PubMed. A seguinte estratégia utilizada: "randomized controlled trial"[Publication Type] OR trials as topic"[MeSH Terms] trial"[All Fields]. manual também realizada. Resultados: apresenta discute os seguintes tópicos grande importância estudos randomizados: randomizados, itens metodológicos...