A5074872021- Dialysis and Renal Disease Management
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Healthcare Policy and Management
- Central Venous Catheters and Hemodialysis
- Renal Transplantation Outcomes and Treatments
- Diabetes and associated disorders
- Vascular Procedures and Complications
- Reproductive Health and Technologies
- Capital Investment and Risk Analysis
- Diabetes Management and Research
- Organ Donation and Transplantation
- Adolescent and Pediatric Healthcare
- Palliative Care and End-of-Life Issues
- Organ Transplantation Techniques and Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Kidney Disease and Diabetes
- Blood Pressure and Hypertension Studies
- Radiation Dose and Imaging
- Renal and Vascular Pathologies
- Acute Kidney Injury Research
- Transplantation: Methods and Outcomes
- Pancreatic function and diabetes
- Ovarian function and disorders
- Neurological Complications and Syndromes
University of California, San Francisco
2016-2025
University of California, Los Angeles
2018-2024
University of California System
2016-2023
King's Fertility
2022
King's College Hospital
2022
UCLA Health
2018-2020
Berry (United States)
2016-2017
Courant Institute of Mathematical Sciences
2017
New York University
2017
Agency for Toxic Substances and Disease Registry
2016
Purpose To develop and validate a deep learning algorithm that predicts the final diagnosis of Alzheimer disease (AD), mild cognitive impairment, or neither at fluorine 18 (
Radiomics is an emerging technology for imaging biomarker discovery and disease-specific personalized treatment management. This paper aims to determine the benefit of using multi-modality radiomics data from PET MR images in characterization breast cancer phenotype prognosis. Eighty-four features were extracted 113 patients. Unsupervised clustering based on MRI radiomic created three subgroups. These derived subgroups statistically significantly associated with tumor grade (p = 2.0 × 10-6),...
Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease, is a progressive and fatal neuromuscular disease for which no cure or viable treatment has been identified. ALS, like most noncommunicable diseases, not nationally notifiable in the United States. The prevalence of ALS States during 2010-2011 was estimated to be 3.9 cases per 100,000 persons general population. Updated estimates are needed help monitor status, better understand etiology, identify risk factors...
Background: There has been a recent trend towards starting dialysis at higher estimated glomerular filtration rates (eGFRs) in children, with no identified survival benefits. We aimed to determine whether there are similar trends the timing of preemptive kidney transplant and eGFR (≥15 ml/min/1.73 m 2 ) was associated clinical outcomes among US children. Methods: performed retrospective cohort study 1,514 children United States Renal Data System who received between 2006-2019. In primary...
Background and Objectives: Prior research has linked higher body-mass index (BMI) greater visceral adiposity with more rapid progression of early-stage autosomal dominant polycystic kidney disease (ADPKD). We now evaluate the association between overweight obesity in early- late-stage patients ADPKD to end-stage (ESKD). Design, Setting, Participants, Measurements: Participants (Study A; N=556; eGFR: 91±17 mL/min/1.73m 2 ) B; N=483; 48±12 who participated HALT PKD trials were categorized by...
Abstract Background and Objectives Diabetic ketoacidosis (DKA) rates in the United States are rising. Prior studies suggest higher younger populations, but no have evaluated national trends pediatric populations differences by subgroups. As such, we sought to examine DKA. Methods We used 2006, 2009, 2012, 2016 Kids’ Inpatient Database identify DKA admissions among a nationally representative sample of youth ≤20 years old. estimate admission per 10 000 population, charges, length stay (LOS),...
Significance Statement The Advancing American Kidney Health Initiative aims to increase rates of utilization peritoneal dialysis (PD) in the United States. One first steps PD is successful catheter placement, which can be performed by surgeons, interventional radiologists, or nephrologists. We examined association between operator subspecialty and risk needing a follow-up procedure 90 days after initial implantation. Overall, we found that 15.5% catheters required revision, removal, second...
There are limited data on the degree of variability in practices surrounding prioritization referrals for transplant evaluation and criteria candidacy their association with transplantation rates. We surveyed programs across United States between January 2020 May to determine current pre-transplantation practices. examined relation these reported outcomes waitlisted patients at responding 2015 March 2021 using Scientific Registry Transplant Recipients data. used adjusted Cox models random...
Background. Hyponatremia before liver transplant (LT) increases risk of post-LT neurological complications in patients with decompensated cirrhosis, but it is unknown to what extent change sodium from pre- influences central nervous system (CNS) sequelae. We assessed the relationship between delta and prevalence CNS during LT hospitalization. Methods. performed retrospective single-center chart review 1265 adults cirrhosis who underwent (2011–2020). Delta defined as difference maximum within...
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There is a paucity of data on the risk factors for hyperosmolar hyperglycemic state (HHS) compared with diabetic ketoacidosis (DKA) in pediatric type 2 diabetes (T2D).We used national Kids' Inpatient Database to identify admissions DKA and HHS among those T2D years 2006, 2009, 2012, 2019. Admissions were identified using ICD codes. Those aged <9yo excluded. We descriptive statistics summarize baseline characteristics Chi-squared test logistic regression evaluate associated admission...
Background Use of eGFR to determine preemptive waitlisting eligibility may contribute racial/ethnic disparities in access waitlisting, which can only occur when the falls ≤20 ml/min per 1.73 m 2 . an alternative risk-based strategy for reduce these inequities ( e.g. , a kidney failure risk equation [KFRE] estimated 2-year failure) rather than standard threshold determining waitlist eligibility. Our objective was model amount waittime that could be accrued by race and ethnicity, applying two...
Insulin pump use in type 1 diabetes management has significantly increased recent years, but we have few data on its impact inpatient admissions for acute complications.We used the 2006, 2009, 2012, and 2019 Kids' Inpatient Database to identify all-cause hospital those with without documented insulin failure. We described differences (1) prevalence of complications, (2) severity illness during hospitalization disposition after discharge, (3) length stay (LOS) costs.We identified 228 474...