A5069683136- Bioinformatics and Genomic Networks
- Radiomics and Machine Learning in Medical Imaging
- Cell Image Analysis Techniques
- Machine Learning in Bioinformatics
- Biotin and Related Studies
- Genetics, Bioinformatics, and Biomedical Research
- Medical Imaging Techniques and Applications
- RNA Research and Splicing
- S100 Proteins and Annexins
- Radiopharmaceutical Chemistry and Applications
- Brain Tumor Detection and Classification
- Cell Adhesion Molecules Research
- Virus-based gene therapy research
- Advanced MRI Techniques and Applications
- AI in cancer detection
- Body Image and Dysmorphia Studies
- Virtual Reality Applications and Impacts
- Cytokine Signaling Pathways and Interactions
- Nuclear Structure and Function
- Psychosomatic Disorders and Their Treatments
- bioluminescence and chemiluminescence research
- Immunodeficiency and Autoimmune Disorders
- Muscle activation and electromyography studies
- Action Observation and Synchronization
- Motor Control and Adaptation
University of Zurich
2020-2025
ETH Zurich
2024-2025
Laboratory for Social and Neural Systems Research
2024
Valens Clinics
2023
University Hospital of Zurich
2016-2021
Utrecht University
2021
University of Milano-Bicocca
2016
A hand amputation is a highly disabling event, having severe physical and psychological repercussions on person's life. Despite extensive efforts devoted to restoring the missing functionality via dexterous myoelectric prostheses, natural robust control usable in everyday life still challenging. Novel techniques have been proposed overcome current limitations, among them fusion of surface electromyography with other sources contextual information. We present dataset investigate inclusion eye...
"Body integrity dysphoria" (BID) is a severe condition affecting nonpsychotic individuals. In the amputation variant of BID, limb may be experienced as not being part body, despite normal anatomical development and intact sensorimotor functions. We previously demonstrated altered brain structural (gray matter) functional connectivity in 16 men with BID long-lasting exclusive desire for left leg amputation. Here, we aimed to identify, same sample, patterns white matter connectivity....
Body integrity dysphoria (BID), a long-lasting desire for the amputation of physically healthy limbs, is associated with reduced fMRI resting-state functional connectivity somatosensory cortices. Here, we used to evaluate whether these findings could be replicated and expanded using task-based paradigm. We measured brain activations during stimulation motor tasks each four limbs in ten individuals life-long left leg fourteen controls. For leg, BID had activation right superior parietal...
During the past 60 years scientific research proposed many techniques to control robotic hand prostheses with surface electromyography (sEMG). Few of them have been implemented in commercial systems also due limited robustness that may be improved multimodal data. This paper presents first acquisition setup, protocol and dataset including sEMG, eye tracking computer vision study control. A data analysis on healthy controls gives a idea capabilities constraints procedure will applied amputees...
Motor imagery (M.I.) training has been widely used to enhance motor behavior. To characterize the neural foundations of its rehabilitative effects in a pathological population we studied twenty-two patients with rhizarthrosis, chronic degenerative articular disease which thumb-to-fingers opposition becomes difficult due increasing pain while brain is typically intact. Before and after surgery, underwent behavioral tests measure performance fMRI measurements activity. After affected hand was...
There is a constant reciprocal flow of information between the malleable sensorimotor states body and cognitive functions, some embodied cognition approaches argue that many cognitive-affective mechanisms depend on physical characteristics body. To examine such influences bodily state, current study compared patients with integrity dysphoria (BID) an amputation desire lower limb to healthy control group Implicit Association Test for self-identity self-esteem, pain evaluation task. Patients...
It has been shown that observing a face being touched or moving in synchrony with our own increases self-identification the former which might alter both cognitive and affective processes. The induction of this phenomenon, termed enfacement illusion, often relied on laboratory tools are unavailable to large audience. However, digital filters applications nowadays regularly used provide an interesting tool study similar mechanisms wider population. Digital able render faces real time while...
Asomatognosia designates the experience that one's body has faded from awareness. It is typically a somaesthetic but may target visual modality ("asomatoscopy"). Frequently associated symptoms are loss of ownership or agency over limb. Here, we elaborate on rigorous nosographic classification asomatognosia and introduce structured interview to capture both its core signs bodily estrangement. We additionally report case pure left-sided hemiasomatognosia occurring after surgical removal...
Somatoparaphrenia refers to the delusional belief, typically observed in right brain-damaged patients, that contralesional limbs belong someone else. Here, we aimed uncover neural activity associated with this productive, i.e. confabulatory, component a patient, S.P.P., large right-sided lesion of both cortical and subcortical gray white matter. He claimed his left paralyzed hand belonged mother. In block-design functional magnetic resonance (fMRI) experiment, S.P.P. imagined mother would...
Visual attention is often predictive for future actions in humans. In manipulation tasks, the eyes tend to fixate an object of interest even before reach-to-grasp initiated. Some recent studies have proposed exploit this anticipatory gaze behavior improve control dexterous upper limb prostheses. This requires a detailed understanding visuomotor coordination determine which temporal window may provide helpful information. paper, we verify and quantify motor 14 transradial amputees who were...
Abstract Despite recent advances in prosthetics, many upper limb amputees still use prostheses with some reluctance. They often do not feel able to incorporate the artificial hand into their bodily self. Furthermore, prosthesis fitting is usually tailored accommodate characteristics of an individual’s phantom sensations. These are experienced by almost all persons acquired amputation and comprise motor postural properties lost limb. This article presents validates a multimodal dataset...
During autoscopic phenomena, people perceive a double of themselves in extrapersonal space. Such clinical allocentric self-experiences sometimes co-occur with auditory hallucinations, yet experimental setups to induce similar illusions healthy participants have generally neglected acoustic cues. We investigated whether feeling the presence an could be provoked experimentally by recording participants' own versus another person's voice and movements using binaural headphones from egocentric...
Abstract Hand amputation is a highly disabling event, having severe physical and psychological repercussions on person’s life. Despite extensive efforts devoted to restoring the missing functionality via dexterous myoelectric hand prostheses, natural robust control usable in everyday life still challenging. Novel techniques have been proposed overcome current limitations, among which fusion of surface electromyography with other sources contextual information. We present dataset investigate...
Limb apparent motion perception (LAMP) refers to the illusory visual of a moving limb upon observing two rapidly alternating photographs depicting same in different postures. Fast stimulus onset asynchronies (SOAs) induce more visually guided physically impossible movements. Slow SOAs possible According motor theory LAMP, latter depends observer's sensorimotor representations. Here, we tested this independent studies by performing central (study 1) and peripheral 2) manipulation body's...
Abstract In Body Integrity Dysphoria (BID) a profound incongruity between the physical body and desired, i.e., amputated body, often leads to desire for limb amputation. Virtual reality (VR) multisensory stimulation paradigms provide powerful tools create experience of being embodied in an body. Here we investigate impact such on neural subjective responses 18 individuals with BID controls. We used both task-based resting-state MRI before after participants played immersive virtual game...