A5076215152- Clinical Reasoning and Diagnostic Skills
- Neurological Disease Mechanisms and Treatments
- Electronic Health Records Systems
- Neuroinflammation and Neurodegeneration Mechanisms
- Biomedical Text Mining and Ontologies
- Adolescent Sexual and Reproductive Health
- HIV/AIDS Research and Interventions
- Cytomegalovirus and herpesvirus research
- Antimicrobial Resistance in Staphylococcus
- Neurogenesis and neuroplasticity mechanisms
- Sepsis Diagnosis and Treatment
- Reproductive tract infections research
- Neuroscience and Neuropharmacology Research
- Radiology practices and education
- Immunodeficiency and Autoimmune Disorders
- Hematopoietic Stem Cell Transplantation
- Herpesvirus Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- Machine Learning in Healthcare
- Parvovirus B19 Infection Studies
- Polyomavirus and related diseases
- HIV, Drug Use, Sexual Risk
- Poxvirus research and outbreaks
- Bacillus and Francisella bacterial research
- RNA regulation and disease
University of California, Los Angeles
2016-2025
New York University
2022-2024
UCLA Health
2019
Argerich Hospital
2004
Significance White matter stroke is a common clinical problem that leads to widespread cognitive and sensorimotor deficits. The incidence of white sharply age-associated; imaging studies indicate that, over age 80, virtually all us will have strokes. Little known the repair processes after stroke. Here, we report tissue identify Nogo receptor 1 (NgR1) ligands as inhibitors. We show functional recovery are indeed possible in aged brains when an engineered NgR1 decoy systemically administered...
Sexually transmitted infections (STIs) are associated with adverse outcomes in pregnancy, including mother-to-child HIV transmission. Yet there limited data on the prevalence and correlates of STI pregnant women by status low- middle-income countries, where syndromic management is routine.
Background: Pediatric hematopoietic stem cell transplant (pHSCT) patients are at risk for many life-threatening post-transplant complications, notably relapse, graft-versus-host disease (GvHD), and infection. Methods: This retrospective study reviewed 10 years of pHSCT a single institution, assessing factors post-transplantation viral infections (herpes simplex virus (HSV), varicella-zoster (VZV), Epstein-Barr (EBV), cytomegalovirus (CMV), human herpes 6 (HHV6), adenovirus (ADNV), polyoma 1...
Subcortical white matter stroke is a common subtype. White stimulates adjacent oligodendrocyte progenitor cells (OPCs) to divide and migrate the lesion, but OPCs have only limited differentiation into mature oligodendrocytes. To understand molecular systems that are active in OPC responses stroke, were virally labeled laser-captured region of partial damage infarct male mice. RNAseq indicates two distinct transcriptomes associated with proliferative limited-regeneration phases after stroke....
<title>Abstract</title> <bold>Background</bold> Objective measures and large datasets are needed to determine aspects of the Clinical Learning Environment (CLE) impacting resident performance. Artificial Intelligence (AI) offers a solution. Here, authors sought what CLE might be performance as measured by clinical reasoning documentation quality assessed AI. <bold>Methods</bold> In this observational, retrospective cross-sectional analysis hospital admission notes from Electronic Health...
The 2022 mpox outbreak in New York City posed challenges to rapidly scaling up treatment capacity. We describe a telehealth model launched during this that facilitated healthcare provider capacity, and was able adhere Centers for Disease Control Prevention (CDC)-sponsored expanded access investigational new drug (EA-IND) protocol tecovirimat. Sixty-nine patients were evaluated prescribed tecovirimat through visits at NYC Health + Hospitals/Bellevue NYU Langone from June August 2022....
Pregnant and postpartum women in Southern Africa are at increased risk of HIV infection. Pre-exposure prophylaxis pregnancy periods could significantly reduce the acquisition transmission pregnancy. Participants a community health clinic Cape Town completed survey about demographic sexual behaviors, prior knowledge pre-exposure prophylaxis. We evaluated factors associated with using multivariable logistic regression. enrolled 50 pregnant 37 women, whom 51% were HIV-uninfected. Twenty-nine...
<sec> <title>BACKGROUND</title> Clinical reasoning is an essential skill, yet physicians receive limited feedback. Artificial intelligence holds promise to fill this gap. </sec> <title>OBJECTIVE</title> We report the development of both named entity recognition (NER), logic-based and large language model (LLM)-based assessments CR documentation in electronic health record (EHR) across two institutions. <title>METHODS</title> Two note sets were retrieved from EHR at each institution (NYU...
Clinical reasoning (CR) is an essential skill; yet, physicians often receive limited feedback. Artificial intelligence holds promise to fill this gap. We report the development of named entity recognition (NER), logic-based and large language model (LLM)-based assessments CR documentation in electronic health record across 2 institutions (New York University Grossman School Medicine [NYU] Cincinnati College [UC]). The note corpus consisted internal medicine resident admission notes...
Background: Blood cultures are a fundamental tool in the diagnosis of infections, but they can lead to clinical confusion and waste resources when yield false results. To optimize blood-culture orders at our institution, we developed an evidence-based guideline (Fig. 1) be used by frontline providers on nonneutropenic hospitalized adult inpatients. We retrospectively reviewed charts patients with positive blood evaluate whether infectious diseases (ID) attending physicians were able...
A133 Previous studies proved that patients with Chaga‘s disease showed endothelial dysfunction in all the stages of illness. Aim: To evaluate function renal transplant and to compare them a group no chronic disease. Methods: Sixteen normal left ventricular were studied, eleven (transplant 51± 9 y/o) five (control 43± 12 p = ns. Nine out had hypertension was treated as follows: enalapril=2 patients, losartan=1 patient, beta blockers or channel calcium blockers=8 pts. Two hyperlipidemia one...
Background Umbilical cord blood (UCB) transplantation has been demonstrated to be associated with higher risk of viral infections, but few studies have examined the rates infections and morbidity in pediatric population. Patients methods Retrospective assessment all patients who received an UCB transplant at UCLA from January 2007 December 2017. Pre-transplant screening included serologies for CMV, HSV, EBV hepatitis viruses. Prophylaxis was administered seropositive CMV consisting...
Background: Staphylococcus aureus is a common cause of healthcare associated infections and with high mortality. S. colonization skin mucosa contributes to its pathogenesis. Universal aureu s decolonization reduces methicillin-resistant (MRSA) other bloodstream among ICU patients. However, universal in acute-care settings has not shown similar benefit. We describe targeted protocol implemented at large academic hospital across intensive care settings. assessed the impact on –related...
Abstract Background Staphylococcus aureus is a common cause of healthcare associated infections and with high mortality. Universal S. decolonization reduces methicillin-resistant (MRSA) other bloodstream among ICU patients. However, universal in acute care settings has not shown similar benefit. We describe screening targeted protocol implemented at an academic hospital across intensive settings. The goal this study was to assess the impact on rates invasive infections. Methods Adult...