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Anna Ng

ORCID: 0000-0002-3902-4769
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About
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A5104302246
Research Areas
  • Galectins and Cancer Biology
  • Monoclonal and Polyclonal Antibodies Research
  • Glycosylation and Glycoproteins Research

Columbia University
 2025

Columbia University Irving Medical Center
 2022

 Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathy
OPENALEX - Publications 
Sindhuri Prakash Nicholas J. Steers Yifu Li Elena Sánchez Miguel Verbitsky and 30 more Isabel Robbins Jenna Simpson Sharvari Pathak Milan Raška Colin Reily Anna Ng Judy Liang Natalia DeMaria Amanda Katiraei Kelsey O'Stevens Clara Fischman Samantha L. Shapiro Susheel Kodali J. Allen McCutchan Heekuk Park Djamila Eliby Marco Delsante Landino Allegri Enrico Fiaccadori Monica Bodria Maddalena Marasà Elizabeth Raveché Bruce A. Julian Anne‐Catrin Uhlemann Krzysztof Kiryluk Hong Zhang Vivette D. D’Agati Simone Sanna‐Cherchi Jan Novák Ali G. Gharavi

Aberrant O-glycosylation of the IgA1 hinge region is a characteristic finding in patients with IgA nephropathy (IgAN) and thought to contribute immune-complex formation kidney injury. Other studies have suggested that abnormalities mucosal immunity lymphocyte homing are major contributors disease. We identified family IgAN segregating heterozygous predicted loss-of-function (LOF) variant GALNT14, gene encoding N-acetylgalactosaminyltransferase 14, one enzymes involved mucin-type protein...

10.1172/jci181164 article EN cc-by Journal of Clinical Investigation 2025-03-18
 Analysis of Galnt14 Null Mice Link O-Glycosylation Defects With Elevated IgA Levels via Altered B-Cell Homing
OPENALEX - Publications 
Nicholas J. Steers Sindhuri Prakash-Polet Kelsey O. Stevens Anna Ng Judy Liang and 2 more Jan Novák Ali G. Gharavi

10.1681/asn.20223311s1779b article EN Journal of the American Society of Nephrology 2022-11-01
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