Amaç: Bu çalışmada, endometrioid tip endometrium kanserli vakaların üç boyutlu – transvajinal ultrasonografi ile preoperatif endometrial volüm ölçümlerinin hem intraoperatif frozen sonuçları de nihai patoloji karşılaştırılması hedeflenmiştir. Gereç ve Yöntem: ÇEndometrial biyopsi gelen, operasyon için hospitalize edilen tüm kanseri hastalarına operasyondan hemen önce GE Voluson E6 cihazı probu kullanılarak yapıldı. Endometrial ölçümü, uterin total ölçümü VOCAL yöntemi kullanılarak; kalınlığı...

In the present study, it was aimed to screen genotypes of human papillomavirus (HPV) retrospectively in women with gynecological symptoms who were admitted a tertiary care university hospital Ankara, Turkey. A total 4267 cervical swab samples aged 18-79 years sent Medical Virology Laboratory from January 2017 November 2020. Nucleic acid extraction and amplification done by an automated system. The test can detect 14 high-risk HPV (HR-HPV) types single analysis that performs real-time...

Increasing awareness of human papilloma virus (HPV) and vaccines among the target population is an important factor for decreasing rate malignancies related to HPV. The aim this cross-sectional study was determine Turkish high school college students' knowledge level HPV via a survey. scale (HPV-KS) has been developed measure about vaccination. response 'Yes' question whether participants have heard vaccine 60.8% 58.8%, respectively. lack information commonest reason not being vaccinated in...

SUMMARY OBJECTIVE: The aim of this study was to assess the results and efficiency two real-time polymerase chain reaction procedures for detecting human papillomavirus utilizing urine samples. METHODS: This comprised 151 patients who had previously tested positive in their cervical Two different commercial techniques were used identification genotyping specimens. samples evaluated via Roche Cobas test, 91 also Qiagen test. RESULTS: overall consistency swab specimens tests 44.8 44%,...

The aim of this study is to evaluate the expressions programmed death-ligand 1 (PD-L1), V-domain Ig suppressor T-cell activation (VISTA), lymphocyte gene-3 (LAG-3), and galectin-3 (GAL-3), in mismatch repair-deficient (MMRd)/MMR-proficient abnormal p53 expressing endometrial carcinomas their relationship with clinical-histopathological features. Patients who underwent surgery for carcinoma between January 2008 December 2018 were included study. Immunohistochemical analysis MLH1 , PMS2, MSH2,...

The objective of this study was to analyze the genetic alterations tumors within scope homologous recombination deficiency gene panel in patients diagnosed with synchronous endometrial ovarian cancer who have been followed for over 5 years using next-generation sequencing.

Objective: The goal of cervical screening is to identify and treat high grade intraepithelial neoplasia (HSIL), in order reduce the incidence cancer. objective this investigation was analyze sensitivity detection rate HSIL urine samples from those who tested status for HPV, as well assess contrast histopathological findings HPV-positive individuals specimens. Materials Methods: This study comprised 151 patients had previously positive HPV their samples. commercial real-time PCR techniques...

Objective: The dysregulation of metabolism is a hallmark cancer. Enzymes tricarboxylic acid (TCA) cycle have key role in pathogenesis carcinogenesis as oncometabolits. variants fumarate hydratase (FH) gene been linked to sporadic tumors and familial tumor propensity. To asses the prevalence FH endometrial carcinoma (EC) uterine leiomyomas (UL). Material Methods: This prospective study included 58 patients with EC 44 UL. were analyzed DNA samples collected from peripheral circulation. All...

Kanser, fonksiyonu hücre büyümesi ve DNA’nın bütünlüğünü koruma olan genlerdeki mutasyonlar sonucu gelişir. Mutasyonlar, germ hücrelerinde(germline)(GLM) diğer hücrelerde (somatik)(SM) olabilir. Kanserlerin %5-10’undan germline sorumludur. Erken dönemde GLM’ların tespit edilmesi; risk altındaki bireylerin belirlenmesi, takibinin yapılması azaltıcı koruyucu stratejilerin geliştirilmesi açısından önemlidir. Ayrıca son zamanlarda tümör dokusunda SM’ların tespiti, hedefe yönelik adjuvan tedaviyi...

Background/Aim: Turner syndrome (TS) is a genetic failure that influence phenotypic girls who have full or incomplete monosomy of X chromosome with variety clinical signs. The purpose this study was to estimate TS cases based on their cytogenetic findings and implications.

OBJECTIVE: Mature cystic teratoma, also known as a dermoid cyst, is the most common germ cell tumor of ovary. In this retrospective study, it aimed to evaluate clinicopathological findings patients who were operated on due preliminary diagnosis cyst. STUDY DESIGN: Between May 2013 and 2018, total 143 with cyst in our institution analyzed retrospectively. addition demographic characteristics such age, parity number size, lateralization, preoperative markers, surgical procedure, presence other...

Aim: Ovarian fibroma, fibrothecoma and thecoma are benign neoplasia of the ovary. The aim this study is to analyze clinical characteristics, histopathological results surgical management ovarian fibroma/fibrothecoma.Materials Methods: This a retrospective 51 cases who underwent treatment because adnexial mass. reported as fibroma/fibrothecomas were analyzed.Results: mean age patients 58.7 years old. avarage diameter tumours was 8.23 cm. final pathological fibrothecoma, celluler mitotic...