A5091781501- Electrospun Nanofibers in Biomedical Applications
- biodegradable polymer synthesis and properties
- Advanced Sensor and Energy Harvesting Materials
- Advanced Polymer Synthesis and Characterization
- Nanocomposite Films for Food Packaging
- Polymer Surface Interaction Studies
- Synthesis and properties of polymers
- Conducting polymers and applications
- Silk-based biomaterials and applications
- Polymer Nanocomposite Synthesis and Irradiation
- Hydrogels: synthesis, properties, applications
- Fiber-reinforced polymer composites
- Silicone and Siloxane Chemistry
- Chemistry and Chemical Engineering
- Graphene research and applications
- Biopolymer Synthesis and Applications
- Fullerene Chemistry and Applications
- Carbon Nanotubes in Composites
- Antimicrobial agents and applications
- Electrochemical sensors and biosensors
- Curcumin's Biomedical Applications
- History and advancements in chemistry
- Surfactants and Colloidal Systems
- Advanced Drug Delivery Systems
- Photopolymerization techniques and applications
Bulgarian Academy of Sciences
2015-2024
Institute of Polymers
2015-2024
Military Medical Academy
2009-2010
University of Mons
2007-2010
Institute of Molecular Biology
2007-2009
University of Liège
2006
Centre National de la Recherche Scientifique
1996
Université de Montpellier
1996
Institut National des Sciences Appliquées de Lyon
1977
Institut de Chimie
1971
PLA/PEO/PLA triblock copolymers bearing short poly(l-lactic acid) blocks, with the number average degree of polymerization each PLA block = 2, 4, 8, and 12, were synthesized by ring opening l-lactide initiated poly(ethylene glycol) in presence CaH2. The length PEO blocks was varied using parent PEG different degrees 14, 26, 49, respectively, according to SEC NMR. 1H 13C NMR showed resulting did not contain any detectable homopolymer as side product. use DMSO-d6 solvent for analyses, instead...
A series of triblock PLA/PEO/PLA copolymers were synthesized by polymerization l-lactide in the presence PEG2000, a bifunctional OH-terminated poly(ethylene glycol) (M̄n = 1800) using Zn metal or CaH2 as catalyst. The resulting analyzed various techniques including 1H and 13C nuclear magnetic resonance, size-exclusion chromatography, X-ray diffractometry, optical microscopy, differential scanning calorimetry. NMR spectra showed that catalyzed lactide under selected experimental conditions to...
1H and 13C NMR analyses of l- d.l-lactic acid oligomers were found considerably improved by recording spectra in DMSO-d6 instead CDCl3. Systematic comparison oligomer led to the identification a neighboring effect which was shown be linearly additive. Assignment all chemical shifts belonging different constitutive units realized up octamer. Furthermore, well-identified positions resonances chain end used determine absolute average degree polymerization issued from polycondensation. Data also...
Abstract Continuous defect‐free nanofibers containing chitosan (Ch) or quaternized (QCh) were successfully prepared by one‐step electrospinning of Ch QCh solutions mixed with poly[( L ‐lactide) ‐co‐ ( d,l ‐lactide)] in common solvent. XPS revealed the surface chemical composition bicomponent electrospun mats. Crosslinked Ch‐ and QCh‐containing exhibited higher kill rates against bacteria S. aureus E. coli than corresponding solvent‐cast films. SEM observations showed that hybrid mats very...
Nanofibrous materials containing the antitumor drug doxorubicin hydrochloride (DOX) were easily prepared using a one-step method by electrospinning of DOX/poly(l-lactide-co-d,l-lactide) (coPLA) and DOX/quaternized chitosan (QCh)/coPLA solutions. The pristine DOX-containing mats characterized ATR-FTIR X-ray photoelectron spectroscopy (XPS). release rate DOX from fibers increased with increase in content. process was diffusion-controlled. MTT cell viability studies revealed that incorporation...
Abstract The first successful preparation of chitosan-containing nanofibres was achieved by electrospinning chitosan/poly(ethylene oxide) (PEO) blend aqueous solutions. diameters the were in range 40 - 290 nm and decreased with increasing chitosan content decreasing total concentration. An increase applied field strength leads to an diameter a broadening size distribution. possibility prepare containing model drug potassium 5-nitro-8-quinolinolate (K5N8Q), broad-spectrum antimicrobial...
Poly(L-lactide) (PLLA)/polyethylene glycol (PEG) mixed solutions were successfully electrospun into micro-or nanofibrous polymer mats. The fiber diameter was in the range 100nm-6μm. effect of concentration spinning and ratio PLLA/PEG on morphology investigated. hydrophilicity tuned by varying ratio. tissue compatibility scaffolds screened using two different cell models human dermal fibroblasts osteoblast-like line MG-63. Both types cells attached uniformly approximately equally to all...
Novel fibrous materials of stereocomplex between high-molecular-weight poly(d- or l-)lactide (HMPDLA HMPLLA) and diblock copolymers consisting poly(l- d-)lactide poly(N,N-dimethylamino-2-ethyl methacrylate) blocks, respectively (PLLA-block-PDMAEMA PDLA-block-PDMAEMA), were prepared by solution electrospinning. Fibers with mean diameters ranging from 1400 to 1700 nm obtained. The formation was evidenced differential scanning calorimetry (DSC) X-ray diffraction (XRD) analyses. Annealing at 100...
Microfibrous materials with a targeted design based on poly(L-lactic acid) (PLA) and poly(!-caprolactone) (PCL) were prepared by electrospinning combining electrospraying.Several approaches used: (i) of common solution the two polymers, (ii) simultaneous separate solutions PLA PCL, (iii) in conjunction electrospraying PCL solution, (iv) alternating layer-by-layer deposition solutions.The mats heated at melting temperature (60°"), thus achieving fibers/particles thermal sealing fibers.The...