A5074499144- Bacterial Genetics and Biotechnology
- Bacterial biofilms and quorum sensing
- Antibiotic Resistance in Bacteria
- Inhalation and Respiratory Drug Delivery
- Vibrio bacteria research studies
- Plant Reproductive Biology
- Polysaccharides and Plant Cell Walls
- Plant Molecular Biology Research
- Lipid Membrane Structure and Behavior
McGill University
2011-2014
Bacteria become highly tolerant to antibiotics when nutrients are limited. The inactivity of antibiotic targets caused by starvation-induced growth arrest is thought be a key mechanism producing tolerance. Here we show that the tolerance nutrient-limited and biofilm Pseudomonas aeruginosa mediated active responses starvation, rather than passive effects arrest. protective controlled starvation-signaling stringent response (SR), our experiments link SR-mediated reduced levels oxidant stress...
As a ubiquitous environmental organism and an important human pathogen, Pseudomonas aeruginosa readily adapts responds to wide range of conditions habitats. The intricate regulatory networks that link quorum sensing other global regulators allow P. coordinate its gene expression cell signaling in response different growth stressors. Upon nutrient transitions starvation, as well stresses, the stringent is activated, mediated by signal (p)ppGpp. produces family molecules called HAQ...
The function of a putative galacturonosyltransferase from Arabidopsis (Arabidopsis thaliana; At1g02720; GALACTURONOSYLTRANSFERASE-LIKE5 [AtGATL5]) was studied using combination molecular genetic, chemical, and immunological approaches. AtGATL5 is expressed in all plant tissues, with highest expression levels siliques 7 DPA. Furthermore, its positively regulated by several transcription factors that are known to regulate seed coat mucilage production. localized both endoplasmic reticulum...