- RNA Interference and Gene Delivery
- Extracellular vesicles in disease
- Transgenic Plants and Applications
- Electrospun Nanofibers in Biomedical Applications
- Plant tissue culture and regeneration
- Plant Genetic and Mutation Studies
- Silk-based biomaterials and applications
- MicroRNA in disease regulation
Huazhong University of Science and Technology
2020
Wuhan University
2020
China Medical University
2000
Large segmental bone regeneration remains a great challenge due to the lack of vascularization in newly formed bone. Conventional strategies primarily combine scaffolds with seed cells and growth factors modulate osteogenesis angiogenesis. Nevertheless, cell-based therapies have some intrinsic issues regarding immunogenicity, tumorigenesis, bioactivity off-the-shelf transplantation. Exosomes are nano-sized (50-200 nm) extracellular vesicles complex composition proteins, nucleic acids lipids,...