- Hematopoietic Stem Cell Transplantation
- COVID-19 Clinical Research Studies
- Lymphoma Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Neutropenia and Cancer Infections
- Inhalation and Respiratory Drug Delivery
- Renal Transplantation Outcomes and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Acute Myeloid Leukemia Research
- Chronic Lymphocytic Leukemia Research
- Antibiotics Pharmacokinetics and Efficacy
- Antimicrobial Resistance in Staphylococcus
- Polyomavirus and related diseases
- Lipoproteins and Cardiovascular Health
- Pharmacological Receptor Mechanisms and Effects
- Blood disorders and treatments
- Parvovirus B19 Infection Studies
- Respiratory and Cough-Related Research
- Cholinesterase and Neurodegenerative Diseases
- Viral-associated cancers and disorders
- Infective Endocarditis Diagnosis and Management
- Long-Term Effects of COVID-19
- Medicinal Plants and Neuroprotection
- Organ Transplantation Techniques and Outcomes
- Asthma and respiratory diseases
Inonu University
2020-2023
Turgut Özal Tıp Merkezi
2023
The MAO enzyme is presented in the brain and peripheral tissues a significant that responsible for deamination of biogenic amines thus regulation neurotransmitter levels. reaction these neurotransmitters with produces aldehyde free amine. consists two isoforms, MAO-A MAO-B, which are characterized by amino acid sequence, three-dimensional structure, substrate preference, inhibitor selectivity. Dopamine, tyramine, tryptamine substrates both isoforms inhibitors such as clorgiline selegiline,...
The safety profile of favipiravir in patients with severe renal impairment has not been investigated and available data are insufficient. study aimed to compare the incidence favipiravir-associated adverse events amongst varying function statuses.
and comorbidities of the patient (3).Late complications following allo-HSCT include chronic GVHD, idiopathic pneumonia,
We present the case of a 73-year-old male patient who was hospitalised with infective endocarditis, and report an elevation in his blood creatine phosphokinase (CPK) after receiving daptomycin rosuvastatin therapy concomitantly. His previous home-scheduled medications included apixaban, ivabradine, metformin, 20 mg, ginkgo biloba trimetazidine, he continued to receive these at hospital. After three sets cultures were taken, empirical treatment started vancomycin gentamicin. On eighth day...
Aralık 2019'da Çin'in Wuhan şehrinde tanımlanan ve hızla yayılan SARS-CoV-2 virüsü, küresel bir pandemiye yol açmıştır. T.C. Sağlık Bakanlığının önerdiği mevcut tedavi protokolündeki ilaçlar (hidroksiklorokin, azitromisin, lopinavir/ritonavir, favipiravir, tocilizumab) da dâhil olmak üzere, COVID-19 hastalığının tedavisi için henüz kanıtlanmış ilaç yoktur. Bununla birlikte, pek çok molekülün in vitro veya klinik çalışmalarla etkinliği araştırılmaktadır. Arbidol, ribavirin, niklozamit,...
Objective: In this study, we aimed to investigate the association between inhaler use skills and general anxiety or coronavirus scores in patients with respiratory diseases. Material Method: Inhaler techniques of 70 asthma chronic obstructive pulmonary disease (COPD) were evaluated by three clinical pharmacists. A pulmonologist assessed patients' using Hamilton Anxiety Rating Scale (HAM-A) Coronavirus (CAS). We used IBM SPSS 25.0 as a software program for related statistical analysis Result...
Objective: Medication nonadherence (MNA) is a main problem in patients with asthma and COPD. Association of anxiety MNA confusing not clear. Improper inhaler technique an unintentional component MNA. In this study, we aimed to investigate the association between medication usage skills general or coronavirus scales. Materials methods: Inhaler techniques 70 COPD were evaluated by three clinical pharmacists. The scores calculated pulmonologist according Hamilton Anxiety Rating Scale (HAM-A)...
Şiddetli akut solunum sendromu-koronavirüs-2, Aralık 2019'da Çin'in Wuhan şehrinde tespit edilmiş yeni bir koronavirüstür. Koronavirüs hastalığı-2019 [coronavirus disease-2019 (COVID-19)] için spesifik terapötik ajan mevcut değildir. Hastalığın tedavisi ve yayılımının önlenmesi seyahat kısıtlamaları, hasta izolasyonu destekleyici tıbbi bakım ile sağlanmaktadır. T.C. Sağlık Bakanlığı COVID19 tedavi kılavuzunda hidroksiklorokin, lopinavir/ritonavir, azitromisin, favipiravir interlökin-6...
Objective: Similar to other regimens, the specific role of fludarabine-amsacrine-cytarabine (FLAMSA) regimen before allogeneic transplantation has still unclear. We compared results patients who received either FLAMSA or busulfan-fludarabine (BuFlu) prior transplantation.
 Materials and Methods: Patients underwent administered reduced-intensity conditioning (RIC) regimens were included in this study. divided into two groups (BuFlu FLAMSA) according applied RIC regimens.
 Results: A...
The aim of this trial is to investigate the risk factors BK viruria and effect on mortality in patients undergoing hematopoietic stem cell transplantation (HSCT). data 247 who underwent HSCT between 01.01.2011-01.12.2017 Inonu University Faculty Medicine Department Hematology were retrospectively analyzed. was defined as positive at any copy level urine. Of patients, 97 (39.2%) detected have virus-positive. Patients with virus urine younger than negative multiple myeloma had a lower rate...
Aim: Vincristine-doxorubicin-dexamethasone (VAD) was the commonly used first-line treatment for multiple myeloma (MM) patients with renal failure before bortezomib entered clinical practice. In this trial, we aimed to compare effect of VAD and bortezomib-cyclophosphamide-dexamethasone (VCD) chemotherapy regimens on improving kidney function in MM failure. Materials Methods: The records our center between January 2010 February 2020 were retrospectively analyzed. Patients who received or VCD...