Po-Hsuan Lai

ORCID: 0000-0002-4061-7107
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About
Contact & Profiles
Research Areas
  • Nutrition and Health in Aging
  • Frailty in Older Adults
  • Barrier Structure and Function Studies
  • Abdominal Trauma and Injuries
  • Pelvic and Acetabular Injuries
  • Appendicitis Diagnosis and Management
  • Alzheimer's disease research and treatments
  • Healthcare cost, quality, practices
  • Bone fractures and treatments
  • Drug Transport and Resistance Mechanisms
  • Cerebral Palsy and Movement Disorders
  • Bladder and Urothelial Cancer Treatments
  • Hip and Femur Fractures
  • Urinary Bladder and Prostate Research
  • Urinary Tract Infections Management
  • Amoebic Infections and Treatments
  • Health Systems, Economic Evaluations, Quality of Life
  • Chronic Disease Management Strategies

I-Shou University
2023-2024

E-Da Hospital
2023-2024

National Cheng Kung University Hospital
2021-2022

National Taiwan University
2021

Abstract Background Rheumatoid arthritis (RA) is characterized by synovial inflammation, cartilage damage, and systemic inflammation. RA also associated with the occurrence of neuroinflammation neurodegenerative diseases. In this study, impacts on function blood-brain barrier (BBB) disposition amyloid beta (Aβ), including BBB transport peripheral clearance Aβ, were investigated in rats collagen-induced (CIA), an animal model similarity to clinical pathological features human RA. Methods CIA...

10.1186/s12974-021-02086-2 article EN cc-by Journal of Neuroinflammation 2021-01-30

The 16-item Physical Resilience Instrument for Older Adults (PRIFOR) has good clinimetric properties; however, a shortened PRIFOR would greatly enhance physical resilience measurements in clinical settings. current analysis aimed to reduce the number of while maintaining its properties, emphasizing on factor structure and convergent validity. A longitudinal study was conducted among 863 patients aged 65 years or older. Four items with high loadings were selected generate short version...

10.1016/j.jnha.2024.100250 article EN cc-by The journal of nutrition health & aging 2024-04-26

Abstract Background Prior studies indicated a link between urinary catheter use and complications, highlighting the need for comprehensive, gender‐specific investigations. This study explored association through national retrospective cohort, emphasizing gender disparities long‐term outcomes. Methods Our utilized data from entire population covered by Taiwan's National Health Insurance Research Database 2000 to 2017. We included 148,304 patients who had undergone Foley placement their...

10.1111/jgs.18819 article EN Journal of the American Geriatrics Society 2024-02-24

Geriatric fractures including distal femur and hip are associated with high mortality rates. Currently, prognostic factors for in-hospital postoperative not identified. We aimed to evaluate overall related potential risk in elderly patients who underwent fracture surgery.A retrospective cohort study of older than 60 years, surgery between January 01, 2003, December 31, 2021, was conducted. A case-control conducted compare two age-matched groups equivalent ages at a 1:4 ratio. The rate...

10.1051/sicotj/2023035 article EN cc-by SICOT-J 2023-01-01

Health problems in older adults are often concomitant with multiple comorbidities and geriatric syndromes that involve the psychological social domains. Traditional models of disease care address health inadequately. Therefore, we applied a case management framework (assess, plan, act, coordinate, evaluate interact) to discuss how implement an elderly-centered approach integrated integrates comprehensive, multidisciplinary, continuous care. The Geriatrics Formulated by Outcome Related Care &...

10.6224/jn.202204_69(2).03 article EN PubMed 2022-04-01

<p>脾膿瘍是很少見的疾病,但若延誤診斷則有高致死率,好發於免疫功能不全患者譬如有糖尿病或肝硬化等疾病。由於糖尿病及癌症盛行率的增加及免疫抑制劑的使用,使得脾膿瘍盛行率有逐漸增加的趨勢。</p> <p>本篇個案報告為一位56歲男性,過去有高血壓及酒精性肝硬化病史,此次因畏寒、倦怠及左上腹痛至門診就醫。理學檢查發現肝脾腫大,超音波顯示肝臟腫大且邊緣不規則,脾臟有一個低迴音性病灶,經腹部電腦斷層證實為多葉型脾膿瘍。病人住院後,接受超音波導引之膿瘍引流及使用抗生素治療,順利出院。希望藉此個案報告,讓基層醫師在鑑別診斷左上腹痛時,能想到可能是少見但有致命危險的脾膿瘍,尤其是遇到肝硬化、糖尿病或免疫不全病史的病人。</p> <p> </p><p>Splenic abscess is an uncommon but complicated disease whose risk of mortality increases with delayed diagnosis and...

10.53106/168232812021123104007 article EN 台灣家庭醫學雜誌 2021-12-01
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