Abstract Mesenchymal stem cells (MSCs) have been the focus of an emerging treatment for osteoarthritis. However, few studies reported about outcomes intra-articular injection autologous adipose-derived mesenchymal (AD-MSCs). This study aimed to assess efficacy and safety a single AD-MSCs patients with knee It was prospective double-blinded, randomized controlled, phase IIb clinical trial. were administered 12 (MSC group), group compared knees normal saline (control group) up 6 months. All...

Background: Gait disturbances characterized by asymmetries in lower limb strength and gait patterns are frequently observed stroke patients, which increases variability fall risk. However, the extent to asymmetry influences this population remains unclear. Methods: This cross-sectional study included 84 participants, comprising survivors age- sex-matched healthy older adults. A portable dynamometer was used assess strength, inertial measurement units analyze parameters. Asymmetry indices...

Deep learning (DL) is an advanced machine approach used in diverse areas, such as image analysis, bioinformatics, and natural language processing. A convolutional neural network (CNN) a representative DL model that advantageous for recognition classification. In this study, we aimed to develop CNN detect meniscal tears classify tear types using coronal sagittal magnetic resonance (MR) images of each patient.We retrospectively collected 599 cases (medial meniscus = 384, lateral 167, medial...

Background and Objectives: This study aimed to investigate the prevalence of sarcopenia in patients undergoing total knee arthroplasty (TKA) for advanced osteoarthritis (OA), assess whether accompanying OA affects patient-reported outcome measures (PROMs) after TKA. We evaluated which predisposing factors could influence development with OA. Material Methods: A 445 whose body composition, muscle strength, physical performance be measured before primary TKA were enrolled. Sarcopenia was...

Background: The purpose of this study was to evaluate the clinical and radiographic results treatment AO/OTA type C pilon fracture via anterolateral approach using a low-profile plate combined with medial minimally invasive osteosynthesis (MIPO). Methods: We retrospectively reviewed 28 ankles fractures that were treated MIPO. Mean age 46 years (range, 19 75), mean follow-up period 25 months 14 50). Clinical assessed visual analogue scale (VAS) American Orthopaedic Foot & Ankle Society...

The aim of this study was to investigate whether the degree patellar cartilage loss confirmed during index surgery affects clinical and radiologic outcomes total knee arthroplasty (TKA) performed without resurfacing.We prospectively divided 2012 patients with a minimum follow-up 12 months into two groups according intraoperatively graded lesions using International Cartilage Repair Society (ICRS) system: group 1, grades 0‒2 (n = 110); 2, 3‒4 102). Relevant locations, such as medial, lateral,...

Mesenchymal stem cells (MSCs) are emerging as an attractive option for osteoarthritis (OA) of the knee joint, due to their marked disease-modifying ability and chondrogenic potential. MSCs can be isolated from various organ tissues, such bone marrow, adipose tissue, synovium, umbilical cord blood, articular cartilage with similar phenotypic characteristics but different proliferation differentiation potentials. They differentiated into a variety connective tissues bone, cartilage,...

This study aimed to assess the clinical and radiological outcomes of hybrid fixation for Danis-Weber type C ankle fractures with a syndesmotic injury.From January 2016 April 2018, we retrospectively reviewed consecutive patients who underwent injury minimum follow-up 12 months. We excluded achieved syndesmosis stability after fracture fixation. In all patients, allowed partial weightbearing at 4 weeks postoperatively. evaluated visual analog scale pain, Olerud-Molander score, American...

Abstract The aim of this study was to investigate the overall incidence venous thromboembolism (VTE) and assess efficacy chemoprophylaxis prevent VTE following medial open-wedge high tibial osteotomy (MOWHTO) in Asian patients. A total 133 patients who consecutively underwent MOWHTO for treatment knee osteoarthritis with varus deformity were enrolled. All preoperative ultrasonography computed tomography venography on postoperative day 5 detect deep vein thrombosis (DVT). Patients divided...

We aimed to evaluate the 5-year follow-up outcomes of an intra-articular bone marrow aspirate concentrate (BMAC) injection in patients with knee osteoarthritis. This is first study report following BMAC injections over a period. Seventy knees 37 patients, including 33 bilateral knees, were investigated. The primary outcome was visual analogue scale (VAS) score for pain joint, and secondary International Knee Documentation Committee score, 36-Item Short Form Health Survey injury...

Friction Stir Welding (FSW) was developed, it is successfully commercialized in the field of transportation vehicles. In this study, we analyzed defects A2024-T4 alloy using non-destructive test radiograph, ultrasonic, electrical conductivity and destructive microstructure observation, tensile strength. As results experiment, mapping obtained. Fine which were not detected radiograph ultrasonic test, enabled efficient detection by difference sound pressure color. The values decreased as...