- COVID-19 Clinical Research Studies
- Asthma and respiratory diseases
- Energy and Environment Impacts
- Respiratory and Cough-Related Research
- Air Quality and Health Impacts
- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- COVID-19 and Mental Health
- Inhalation and Respiratory Drug Delivery
- SARS-CoV-2 and COVID-19 Research
- Medical Imaging and Pathology Studies
- Immunodeficiency and Autoimmune Disorders
- Parasitic Infections and Diagnostics
- Urticaria and Related Conditions
- Heme Oxygenase-1 and Carbon Monoxide
- Amoebic Infections and Treatments
- Sepsis Diagnosis and Treatment
- COVID-19 impact on air quality
- Intestinal Malrotation and Obstruction Disorders
- Lung Cancer Research Studies
- Airway Management and Intubation Techniques
- Cervical and Thoracic Myelopathy
- Gastrointestinal disorders and treatments
- Peripheral Neuropathies and Disorders
- Adrenal Hormones and Disorders
Shahid Sadoughi University of Medical Sciences and Health Services
2013-2024
Sarem Cell Research Center
2020
Hopital Universitaire Hedi Chaker
2008
This study was designed to determine the accuracy of bronchoalveolar lavage fluid cytology (BAL) using histopathologic examination transbronchial biopsy specimens as gold standard in diagnosis lung carcinoma at our center.A retrospective conducted investigate a total 388 patients who were suspected having cancer and had undergone fiberoptic bronchoscopy Shahid Sadoughi hospital from 2006 2011. Lung masses proven be malignant by histology.Transbronchial (TBLB) identified malignancy 183 cases,...
We present an uncommon case of a carcinoid tumour the bronchus that was diagnosed during pregnancy in 28-year-old woman. The patient admitted at emergency department with massive haemoptysis. Owing to patient's critical condition, she underwent urgent flexible bronchoscopy. Bleeding controlled by local injection 500 mg tranexamic acid and electrocautery. After bleeding has stopped, multiple specimens were taken. Histological examination confirmed typical tumour. repeated haemoptysis, treated...
Bronchial anthracosis is caused by the deposition of carbon, silica or asbestos particles in mucosal and submucosal cells macrophages, it can lead to chronic bronchial obstruction. Certain studies have reported an association between infection with Mycobacterium tuberculosis. This study aimed compare samples obtained from bronchoscopy patients without for investigating prevalence tuberculosis.This was a cross-sectional conducted 2010 2013. A total 514 underwent diagnostic pulmonary diseases....
Background Asthma is one of the respiratory disorders caused by chronic airway inflammation. IL-4 has been identified as participating interleukins in severity asthma. Objective A case-control study was conducted to determine association rs1805010, a single nucleotide polymorphism interleukin 4 receptor α chain, with asthma and immunoglobulin E IL-17A serum levels Iranian populations. Methods ELISA used investigate relationship between three different varieties SNP I50V levels, well total...
Background and aims Allergic asthma has a considerable burden on the quality of life. A significant portion moderate-to-severe allergic patients need omalizumab, an anti-immunoglobulin-E monoclonal antibody, as add-on therapy. In this phase III clinical trial P043 (Zerafil ® , CinnaGen, Iran) efficacy, safety, immunogenicity were compared with Xolair (the originator omalizumab). The primary outcome was rate protocol-defined exacerbations. Methods Exacerbation rates, Asthma Control Test (ACT)...
Pulmonary trichomoniasis is an underdiagnosed disease. In most cases, there underlying clinical condition related to immunosuppression. The results of molecular biology techniques indicate that trichomonad infections have been significantly underestimated. A 7-year-old girl with a medical history suspected juvenile rheumatoid arthritis presented fever, chills, and productive cough. Her chest computed tomography scan indicated pericardial effusion consolidation in the left lower lobe. direct...
Introduction: Over the past 20 years, seven coronaviruses have caused more or less severe respiratory diseases in humans. Among these, most important ones are SARS-CoV and coronavirus, a similar virus that has created pandemic called Covid-19 since 2019, belonging to b-category of beta-coronaviruses Sarbecovirus. This is due kind spike-like structure ACE2 receptor (angiotensin converting enzyme 2) bind surface host cells. Often, dysfunction protease after viral infection leads RAAS...
Background: Black dust deposited in the lungs is called anthracosis. By damaging bronchial mucosa, anthracosis can affect mucociliary cleaning function. Initial reports indicate that there a relationship between and pulmonary tuberculosis. Due to obstructive effects of on distal airways disruption proper sampling bronchoalveolar lavage (BAL), other diagnostic methods are necessary for estimating tuberculosis prevalence these patients. The aims this study was evaluate tissue samples adjacent...
Exposure to toxic materials predisposes the lungs infectious agents and inflammatory responses. The present study was performed on patients with anthracosis caused by exposure fossil fuels in previous years, histopathological features of airways' normal-appearing tissue were compared anthracotic plaques these patients.Bronchoscopic evaluations bakery workers who directly contact fuels. Samples taken from (Group A) or seemingly intact tissues at their periphery B). Pathological done after...
Abstract The study was designed to assess the association of ACE I/D polymorphism with severity and prognosis COVID-19 in Iranian population. Hence, 186 adult patients were categorized into three clinical groups based on COVID-19: 1) Outpatients or mild symptomatic as control; 2) Hospitalized severe cases; 3) Inpatients led ICU/death critically ill needed mechanical ventilation. possible risk comorbidities serum level C-reactive protein evaluated two cases. results showed that frequency D I...
Introduction: About 50% of patients with metastatic cancers suffer from malignant pleural effusion. The goals treatment for these should be to relieve pain, restore normal function, reduce or eliminate hospitalization, and make efficient use medical care resources. Objectives: This study aimed evaluate the effect negative pressure suction on success rate pleurodesis bleomycin Patients Methods: was conducted as before-after interventional study, without randomization. For all patients, 1...
<b>Objectives:</b> Gold standard of anthracosis diagnosis is bronchoscopy. Many patients suffer from progressive pulmonary disease for many years after discontinuation exposure to fossil fuel. We hypothesized that smoke inhalation fuels causes diffuse bronchi involvement and it acts like a foreign body inside the therefore inflammation process will continue even in absence fuels. The goal study was compare histopathological features healthy appearing tissue airways with anthracotic plaques...
Introduction: Embryonic development of the gastrointestinal tract is a very complex process and therefore number congenital malformations fetus reported to be numerous varied.The most common site for atresia, after esophagus, duodenum.Duodenal atresia absence or complete blockage part duodenal lumen.This seen in perinatal examinations as polyhydramnios pregnancy ultrasounds.Early detection intestinal obstruction essential prevent further complications.Patient Information: The present study...
Desquamative interstitial pneumonia (DIP) is a form of lung disease that directly related to smoking. In addition smoking, other factors have been implicated in its etiology, including: systemic disorders, dangerous materials the environment, drugs and infectious agents. By reviewing literature, we find there are very rare cases indicate infections as causing DIP. Here author report on 58-year-old male who was addict complained dry cough with dyspnea for one month. TBLB performed pathology...
Investigating the Therapeutic Effect of β-Interferon and Methylprednisolone on COVID- 19 Patients'Consequence: A Non- Randomized, Double-Blinded, Controlled Study
Peripheral neuropathy may be reversible or permanent. Hence, we would like to present a 38-years-old man without any previous medical history admitted ShahidSadoughi Hospital in Yazd terms of reduced force all four limbs, shortness breath, cough and hemoptysis. Electromyography nerve conduction velocity study was performed after the para-clinical examinations Guillain–Barré syndrome considered first diagnosis. Regarding pulmonary symptoms, sinusitis bilateral alveolar opacities, positive...