- Advancements in Battery Materials
- Advanced Battery Materials and Technologies
- Supercapacitor Materials and Fabrication
- Hydrogen Storage and Materials
- Advanced Battery Technologies Research
- Semiconductor materials and interfaces
- Extraction and Separation Processes
- Rare-earth and actinide compounds
- Semiconductor materials and devices
- Advanced battery technologies research
- Ammonia Synthesis and Nitrogen Reduction
- Magnetic Properties of Alloys
- Catalytic Processes in Materials Science
- Gas Sensing Nanomaterials and Sensors
- X-ray Diffraction in Crystallography
- Conducting polymers and applications
- Transition Metal Oxide Nanomaterials
- Crystallization and Solubility Studies
- Advanced Memory and Neural Computing
- COVID-19 Clinical Research Studies
- Chemical Synthesis and Characterization
- Electrocatalysts for Energy Conversion
- Metal and Thin Film Mechanics
- SARS-CoV-2 and COVID-19 Research
- Advanced Chemical Physics Studies
Tottori University
2016-2025
Shionogi (Japan)
2022-2025
Saga University
2025
Osaka University
1989-2023
National Institute for Materials Science
2017-2019
Graduate School USA
2016-2019
Tottori College
2017
Nagoya University
2016
Chiba University
2016
Green Chemistry
2016
This phase 2b part of a randomized 2/3 study assessed the efficacy and safety ensitrelvir for mild-to-moderate coronavirus disease 2019 (COVID-19) during Omicron epidemic.Patients were (1:1:1) to orally receive fumaric acid 125 mg (375 on day 1) or 250 (750 placebo once daily 5 days. The co-primary endpoints change from baseline in severe acute respiratory syndrome 2 (SARS-CoV-2) titer 4 time-weighted average up 120 hours total score predefined 12 COVID-19 symptoms. Safety was through...
We evaluated the charge–discharge performance of a Sn4P3 negative electrode in an ionic liquid electrolyte comprised N-methyl-N-propylpyrrolidinium bis(fluorosulfonyl)amide (Py13-FSA) and NaFSA. also conducted cyclic voltammetry transmission electron microscopy for to reveal reaction mechanism. It was suggested that Na15Sn4 Na3P are formed via phase separation first sodiation elemental Sn P by following desodiation with Na ions subsequent cycles. The exhibited high Coulombic efficiency 99.1%...
Elemental Si has a high theoretical capacity and attracted attention as an anode material for energy density lithium-ion batteries. Rapid fading is the main problem with Si-based electrodes; this mainly because of massive volume change in during lithiation-delithiation. Here, we report that combining ionic-liquid electrolyte charge limit 1000 mA h g-1 significantly suppresses expansion, improving cycle life. Phosphorus-doping also enhances suppression increases Li+ diffusion coefficient. In...
Neutron elastic scattering was used to determine the structure of as-received and lithiated amorphous SiO which has been proposed as an anode material for lithium ion secondary batteries. Based on a comparison between total radial distribution functions it suggested that is composed three-dimensional tetrahedral network similar silica glass metallic silicon clusters, latter were finely dispersed in matrix. On other hand, electrochemically showed typical negative correlation together with...
Rutile-type titanium oxide (TiO2) is a resource-rich and inexpensive material with one-dimensional ion-diffusion path along the c-axis. However, it has received no attention as an anode for Na-ion batteries because of its low electronic conductivity limited ion diffusion in ab-plane direction. We have revealed first time reversible Na insertion–extraction reaction rutile TiO2 recently reported improvement performances by doping various impurity elements such Nb5+, Ta5+, In3+. In this Review,...
As anode materials of Li-ion and Na-ion batteries, the electrochemical insertion/extraction reactions Li Na were investigated for a rutile-type Nb-doped TiO2 synthesized by sol–gel method. We changed particle crystallite sizes rutile powders annealing at various temperatures between 100 1000 °C prepared thick-film electrodes consisting powders. The performances remarkably improved not only in battery but also with reduced temperature 400 from °C. revealed that showing better high-rate...
It is reported that silicon (Si) anodes with a smaller crystallite size show better electrochemical performance in lithium‐ion batteries (LIBs); Si particles different diameters are also used. However, it yet to be clarified whether the attributed or particle diameter. The effect of on its anode using having same diameter and sizes investigated. Longer cycle life obtained for size, due small amount amorphous Li‐rich Li—Si phase formed during charging. likely form greater larger leading...
We investigated the impacts of MnO2 crystal structures and Fe doping into on photoelectrochemical charge–discharge properties composite electrodes composed TiO2 polymorphs (α-, β-, γ-, δ-phases) in aqueous Na2SO4 solution. In a conventional electrochemical capacitor, α-MnO2 electrode delivered highest specific capacitance among undoped because its larger tunnel structure compared with β- γ-MnO2. Since electronic conductivity δ-MnO2 was very low, performance poor despite large interlayer...
This exploratory analysis of the double-blind, phase 3, SCORPIO-SR trial assessed effect ensitrelvir in preventing post coronavirus disease 2019 (COVID-19) condition (PCC). Patients with mild-to-moderate COVID-19 were randomized (1:1:1) within 120 h symptom onset; received 5-day oral 125 mg (375 on day 1), 250 (750 or a matching placebo once daily; and for severity typical PCC symptoms using self-administered questionnaire. In total, 341, 317, 333 patients 125-mg, 250-mg, groups,...
Abstract Background Ensitrelvir is an oral SARS-CoV-2 3CL protease inhibitor developed to treat COVID-19. In the Phase3 SCORPIO-SR trial targeting mild/moderate COVID-19 patients, proportion of patients who experienced Post Condition (PCC) until Day 337 was lower in ensitrelvir groups than placebo group [A. Fukushi et al. The Ninth ESWI Influenza Conference]. Here we report effect on PCC less symptomatic enrolled another part, Phase2b/3. Proportion with Post-COVID-19 and risk reduction...
To address the coronavirus disease 2019 (COVID-19) pandemic, several antiviral agents targeting severe acute respiratory syndrome 2 (SARS-CoV-2) have been developed for clinical use. However, antivirals that can be administered irrespective of risk factors were lacking until approval ensitrelvir fumaric acid (hereafter, ensitrelvir) in Japan, which took effect November 2022. Ensitrelvir is an oral SARS-CoV-2 3C-like protease inhibitor currently approved Japan and Singapore. This narrative...
Thick-film electrodes of composite active materials consisted Si and various metal silicides, FeSi2/Si, VSi2/Si, or MmSi2/Si, were prepared by mechanical alloying followed gas deposition for anodes Li-ion batteries. We investigated a relationship between the performance these properties silicide, electrical resistivity, referential breaking strength, thermodynamic stability. The MmSi2/Si electrode exhibited superb cycling performance, where discharge capacity 380 mA h g-1 was maintained even...
The effect of pre-lithiation on the electrochemical performance Si negative electrodes for lithium-ion batteries was studied. A pre-volume-expansion induced by is expected to decrease relative change in volume during charge-discharge reactions. Suppression should improve cycle performance, Coulombic efficiency, and so on. When mechanically pre-doped Li extracted from Li-Si alloy first cycle, an electrode exhibited poor just like a Si-alone electrode. On other hand, Li1.00Si improved higher...
Single-crystalline Nb-doped TiO2 particles were hydrothermally synthesized for Na-storage materials. Annealing in air changed the particle color from blue to white. The successful introduction of oxygen vacancies into without annealing was confirmed by lattice expansion, reduced electrical resistivity, a Raman peak shift, and presence {110} stacking faults due streaks along ⟨110⟩ reciprocal directions electron diffraction. significantly enhanced reversible capacity electrode because improved...