Sabrina Beaulieu

ORCID: 0000-0002-4133-8417
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About
Contact & Profiles
Research Areas
  • Neuropeptides and Animal Physiology
  • Receptor Mechanisms and Signaling
  • Pain Mechanisms and Treatments
  • Neuroendocrine regulation and behavior

Université de Sherbrooke
2020-2021

Therapeutic hypothermia represents a brain-protective strategy for multiple emergency situations, such as stroke or traumatic injury. Neurotensin (NT), which exerts its effects through activation of two G protein-coupled receptors, namely NTS1 and NTS2 induces strong long-lasting decrease in core body temperature after central administration. Growing evidence demonstrates that is the receptor subtype mediating hypothermic action NT. As such, potent agonists designed on basis minimal...

10.3389/fchem.2020.00406 article EN cc-by Frontiers in Chemistry 2020-06-05
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