A5090421379- Origins and Evolution of Life
- Molecular Spectroscopy and Structure
- Mass Spectrometry Techniques and Applications
- Analytical Chemistry and Chromatography
- Photoreceptor and optogenetics research
- Photosynthetic Processes and Mechanisms
- Astro and Planetary Science
- Advanced Chemical Physics Studies
- Advanced biosensing and bioanalysis techniques
- Molecular Communication and Nanonetworks
- Metabolism, Diabetes, and Cancer
- Block Copolymer Self-Assembly
- Micro and Nano Robotics
- Chemical Analysis and Environmental Impact
- Protist diversity and phylogeny
- Pancreatic function and diabetes
- Diffusion and Search Dynamics
- Gene Regulatory Network Analysis
- Innovation, Sustainability, Human-Machine Systems
- Molecular spectroscopy and chirality
- Spaceflight effects on biology
- Planetary Science and Exploration
- Biochemical and Molecular Research
- Hydrogels: synthesis, properties, applications
- Light effects on plants
AstraZeneca (United Kingdom)
2023
Institut de Chimie de Nice
2014-2021
Université Côte d'Azur
2014-2021
Centre National de la Recherche Scientifique
2014-2021
University of Bristol
2020-2021
Max Planck-Bristol Centre for Minimal Biology
2020
Oxford Research Group
2020
University of Oxford
2020
Institut d'Astrophysique Spatiale
2017
Université Paris-Sud
2017
Making ribose in interstellar ices Astrobiologists have long speculated on the origin of prebiotic molecules such as amino acids and sugars. Meinert et al. demonstrated that numerous can be formed an interstellar-analog sample containing a mixture simple water, methanol, ammonia. They irradiated with ultraviolet light under conditions similar to those expected during formation solar system. This yielded wide variety sugars, including ribose—a major constituent ribonucleic acid (RNA). Science...
The recent devastating pandemic has drastically reminded humanity of the importance constant scientific and technological progress. A strong interdisciplinary dialogue between academic industrial scientists various specialties, entrepreneurs, managers public is paramount in triggering new breakthrough ideas which often emerge at interface disciplines. following sections, compiled by a highly diverse group authors, are summarizing recently achieved game-changing leaps science technology....
Significance In molecular clouds out of which stars and planetary systems form, simple solid-state molecules made in large part H 2 O, CO, CO , CH 3 OH, NH are abundantly present. these environments, energetic thermal processes on ices, can be simulated the laboratory, lead to complex organic matter. Possibly at origin matter our Solar System incorporated into planetesimals, this material may considered as a potential source for prebiotic chemistry telluric planets, following process that...
Photoelectron circular dichroism (PECD) manifests itself as an intense forward/backward asymmetry in the angular distribution of photoelectrons produced from randomly-oriented enantiomers by photoionization with circularly-polarized light (CPL). As a sensitive probe both dynamics and chiral molecular potential, PECD attracts much interest especially recent performance related experiments visible VUV laser sources. Here we report, use quasi-perfect CPL synchrotron radiation using double...
Collective decision making by living cells is facilitated exchange of diffusible signals where sender release a chemical signal that interpreted receiver cells. A variety nonliving artificial cell models have been developed in recent years mimic various aspects diffusion-based intercellular communication. However, localized secretion diffusive from individual protocells, which critical for mimicking biological sender–receiver systems, has remained challenging to control precisely. Here, we...
Life, as it is known to us, uses exclusively L-amino acid and D-sugar enantiomers for the molecular architecture of proteins nucleic acids. This Minireview explores current models original symmetry-breaking influence that led exogenic delivery Earth prebiotic molecules with a slight enantiomeric excess. We provide short overview enhancements detected in bodies extraterrestrial origin, such meteorites, interstellar ices simulated laboratory. Data are interpreted from different points view,...
The detection of biosignatures on Mars is outstanding interest in the current field astrobiology and drives various fields research, ranging from new sample collection strategies to development more sensitive techniques. Detailed analysis organic content analog materials collected extreme environments Earth improves understanding biosignature preservation under conditions similar those Mars. In this article, we examined biological fingerprint several locations Atacama Desert (Chile), which...
Abstract Since the pioneering work of Emanuel Gil‐Av and his associates at Weizmann Institute Science direct gas chromatographic resolution enantiomers has found its application in different fields natural sciences, even expanding to space research astrobiology. In these domains chiral molecules prebiotic relevance is particular interest, since determination ratios between l ‐ d ‐enantiomers within non‐terrestrial samples assumed shed light on origin biomolecular homochirality beginnings...
Abstract The design and synthesis of a novel acid‐degradable polyethylene glycol‐based N ‐hydroxysuccinimide (NHS) ester‐activated crosslinker is reported. reactive towards nucleophiles features central ketal functional group that stable at pH > 7.5 rapidly hydrolyses 6.0. used to (i) fabricate polysaccharide hydrogels exhibit controlled degradation upon exposure an acidic environment or via endogenous enzyme activity; (ii) construct hydrogel‐filled protein‐polymer microcompartments...
Abstract Das uns bekannte Leben kontrolliert den ausschließlichen Gebrauch von L ‐Aminosäure‐ und D ‐Zucker‐Enantiomeren zum molekularen Aufbau Proteinen Nukleinsäuren. In diesem Kurzaufsatz wird aktuellen Modellen Symmetriebruch in Biomolekülen nachgegangen, die Transport erdäußerer präbiotischer Moleküle umfassen. Der stellt Enantiomerenüberschüsse dar, wie sie extraterrestrischen Körpern Meteoriten simuliertem interstellarem Eis nachgewiesen wurden. Die Daten werden aus verschiedenen...
Abstract Chemical reactions occurring within liquid‐liquid phase separated systems drive numerous biological processes and have likely been involved in the emergence of first cellular compartments. Herein we report a reaction whose product distribution is drastically affected by presence interface. Under conditions, system produces dynamic library increasingly complex oligomeric structures. This reactivity sharp contrast to results under homogeneous conditions; when there no separation only...
Abstract Collective decision making by living cells is facilitated exchange of diffusible signals where sender release a chemical signal that interpreted receiver cells. Biologists have started to unravel the underlying physicochemical determinants control effective communication distance using genetically modified However, systems are inherently challenging manipulate and study systematically quantitatively. Therefore, development generic tunable abiotic mimics featuring compartmentalized...
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