Alexandre de Andrade Sousa

ORCID: 0000-0002-4204-9334
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About
Contact & Profiles
Research Areas
  • Head and Neck Cancer Studies
  • Oral health in cancer treatment
  • Thyroid and Parathyroid Surgery
  • Thyroid Cancer Diagnosis and Treatment
  • Oral Health Pathology and Treatment
  • Reconstructive Surgery and Microvascular Techniques
  • Oral and Maxillofacial Pathology
  • Cleft Lip and Palate Research
  • Head and Neck Surgical Oncology
  • Cancer Diagnosis and Treatment
  • Tracheal and airway disorders
  • Tumors and Oncological Cases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Soft tissue tumors and treatment
  • Salivary Gland Tumors Diagnosis and Treatment
  • Dysphagia Assessment and Management
  • Parathyroid Disorders and Treatments
  • Immune cells in cancer
  • Vascular Tumors and Angiosarcomas
  • Colorectal and Anal Carcinomas
  • Sarcoma Diagnosis and Treatment
  • Soft tissue tumor case studies
  • Head and Neck Anomalies
  • Cancer Research and Treatments
  • Inflammatory Biomarkers in Disease Prognosis

Universidade Federal de Minas Gerais
2001-2023

Hospital das Clínicas da Universidade Federal de Minas Gerais
2010-2021

Hashimoto Municipal Hospital
2020

Biocor Institute
2020

Instituto Politecnico de Setubal
2016

University of Beira Interior
2016

Bio-Bras
2014

Federal University of São João del-Rei
2011

Hospital de Clínicas
2010-2011

Hospital de Base
2004

The aim of this study was to evaluate the time elapsed from first symptoms treatment oral and oropharyngeal cancer (OOC) identify variables associated with delay. This is an observational retrospective prospective data collection. Patients a diagnosis OOC seen at Head Neck Surgery outpatient clinic Brazilian public hospital were included followed up initiation. Participants answered questionnaire for collection socioeconomic, demographic, cultural, clinical information, as well information...

10.1590/1807-3107bor-2023.vol37.0054 article EN cc-by Brazilian Oral Research 2023-01-01

To evaluate the incidence and predictors of post-thyroidectomy definitive hypocalcemia hypoparathyroidism.We assessed ionic calcium preoperatively postoperatively (first, second 30th day) in 333 patients undergoing thyroidectomy. In those presenting hypocalcemia, measurements were also made 90 180 days after surgery, when parathormone was dosed. Patients grouped according to presence or absence evaluated age, gender, thyroid function, volume, number parathyroid glands identified need...

10.1590/s0100-69912012000600006 article EN cc-by Revista do Colégio Brasileiro de Cirurgiões 2012-12-01

Salvage laryngectomy in patients treated with organ preservation protocols is associated high rates of postoperative complications. The use non-irradiated tissue flaps pharyngeal reconstruction could reduce the incidence these complications.This study aims to evaluate usefulness pectoralis major myocutaneous flap preventing salivary fistulae during period salvage total (TL).This retrospective enrolled 31 operated between April 2006 and May 2011. All had advanced cancer at time procedure been...

10.1590/s1808-86942012000400019 article EN cc-by Brazilian Journal of Otorhinolaryngology 2012-08-01

magnesium ion concentration is directly related and phosphorus inversely to calcemia. The aim of this study was evaluate the evolution levels in patients undergoing thyroidectomy correlate these with changes calcium concentration.

10.1590/s1516-31802010000500005 article EN cc-by Sao Paulo Medical Journal 2010-01-01

Recent studies have pointed towards a role of tumour-infiltrating neutrophils in cancer biology. Investigations on oral squamous cell carcinoma indicated possible association with clinical characteristics. This study aimed to evaluate neutrophil infiltration and the neutrophil/lymphocyte ratio central areas invasive front carcinomas at different T stages, their clinicopathological features patient outcome. Clinical information was retrieved from charts patients who had undergone surgical...

10.1186/s13104-015-1541-x article EN cc-by BMC Research Notes 2015-10-14

The purpose of this study was to assess the tolerance early oral feeding after total laryngectomy.A randomized multicenter conducted that included 89 individuals subjected laryngectomy. participants were allocated 2 groups: (n = 44), feeding; and late 45), feeding. in group assessed as acceptance feeding, their food intake quantified.In group, energy expenditure protein needs not met through alone at any time during first 7 postoperative days. times attain 25% 50% by surgery 4 days,...

10.1002/hed.24063 article EN Head & Neck 2015-04-01

The aim was to explore the immunophenotype of neutrophils and lymphocytes inflammatory mediators in patients with oral squamous cell carcinoma, comparing controls; associate clinicopathological data.Blood collected from 13 controls. (CD66b, CD16, CD11a, arginase-1), T (CD4, CD8) intracellular cytokine production (IL-10, TNF, IFN-γ) evaluated by flow cytometry. Plasma concentration sVCAM-1, sTNF-RI, sTNF-RII, IL-1β measured ELISA. MPO, Lipocalin-2/NGAL, sICAM-1, p-selectin were quantified...

10.1111/jop.12575 article EN Journal of Oral Pathology and Medicine 2017-03-29

Abstract Objective: This study compared the incidence of salivary fistula between groups with an early or late reintroduction oral feeding, and identified predictive factors for fistula. Methods: A randomised trial was performed using 89 patients larynx hypopharynx cancer, assigned to 2 (early late). In group, feeding started 24 hours after total laryngectomy pharyngolaryngectomy, in it from post-operative day 7 onwards. The occurrence evaluated relation following variables: nutritional...

10.1017/s0022215114000747 article EN The Journal of Laryngology & Otology 2014-04-01

Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm that usually develops in the pleura and peritoneum. The head neck region involved only 6% of cases. Involvement parotid gland phenomenon, with 24 cases reported literature. aim this study to report an additional case SFT affecting gland, review literature on previously patient was 42-year-old male 4-cm, fibro-elastic, movable, painless nodule inferior lobe gland. lesion surgically excised and, following histopathological...

10.4317/jced.51103 article EN Journal of Clinical and Experimental Dentistry 2013-01-01

To evaluate the incidence of pharyngocutaneous fistula after total laryngectomy and try to identify its predictors.From May 2005 April 2010, 93 patients underwent laryngectomy. We evaluated complications during surgery compared them with following variables: gender, nutritional status, previous tracheotomy, tumor location, type surgery, TNM staging, prior treatment chemotherapy and/or radiotherapy, use flaps for reconstruction surgical margin. All presented advanced neoplastic disease...

10.1590/s0100-69912013000200003 article EN cc-by Revista do Colégio Brasileiro de Cirurgiões 2013-04-01

Sodium carboxymethylcellulose (SCMC) has been effective in reducing adhesion formation and corticosteroids reduce the inflammatory process. The objective of this study was to define intraperitoneal (ip) effects SCMC combined with intramuscular (im) methylprednisolone on peritoneal jejunal anastomosis healing rats. Twenty Wistar rats (200-350 g) were divided into four groups (N = 5): I III (controls) 5 21 days treatment before sacrifice, respectively; II IV (experimental groups) treatment,...

10.1590/s0100-879x2001000400012 article EN cc-by Brazilian Journal of Medical and Biological Research 2001-04-01

Several studies show the ability of macrophages to remove particles injected into bloodstream. This function seems be increased in presence acute renal failure. The objective present study was assess phagocytic main organs (spleen, liver and lung) mononuclear system postrenal failures. Fifteen rats (250-350 g) were divided three groups (N = 5): group I - control; II ligature both ureters, III bilateral nephrectomy. On third postoperative day, all animals received an iv injection 1 ml/kg...

10.1590/s0100-879x2001000900010 article EN cc-by Brazilian Journal of Medical and Biological Research 2001-09-01

Schwannomas are benign tumors arising from Schwann cells that affect the peripheral or central nerves. We report case of a patient presented with swelling tongue. The diagnosis was performed through imaging exams, videolaryngoscopy and magnetic resonance (MRI), incisional biopsy. underwent complete transoral resection lesion. rarely found in oral cavity, 46 cases described They present several ways, painless nodules to bulky masses compressive symptoms. Complete surgical excision is...

10.4322/ahns.2020.0016 article EN Archives of Head and Neck Surgery 2020-01-01
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