A5082068103- Carcinogens and Genotoxicity Assessment
- Animal testing and alternatives
- Pesticide Exposure and Toxicity
- Immunotoxicology and immune responses
- Biotechnology and Related Fields
- Effects and risks of endocrine disrupting chemicals
- Biosimilars and Bioanalytical Methods
- Genetically Modified Organisms Research
- Biomedical Ethics and Regulation
- Health Systems, Economic Evaluations, Quality of Life
- Cancer Genomics and Diagnostics
- HER2/EGFR in Cancer Research
- Molecular Biology Techniques and Applications
- Indoor Air Quality and Microbial Exposure
- Monoclonal and Polyclonal Antibodies Research
- Lymphoma Diagnosis and Treatment
- Pharmacogenetics and Drug Metabolism
- Statistical Methods in Clinical Trials
- Contact Dermatitis and Allergies
- Viral Infectious Diseases and Gene Expression in Insects
- Allergic Rhinitis and Sensitization
- Gene expression and cancer classification
- Air Quality and Health Impacts
LabCorp (United States)
2021
Covance (United Kingdom)
2009-2019
Covance (United States)
2007-2011
Current regulatory thinking allows for the use of single control groups rodent carcinogenicity testing although there has been a trend until recently to dual groups. To date, virtually nothing published on whether shift from will affect identification tumorigenic risk potential in these studies. A recent evaluation data rat (Baldrick, Toxicol Pathol 2005, 33: 283–291) showed that no major differences tumor incidences between were found, some interstudy variation occurred and cases notable...
The Ames test has established use in the assessment of potential mutagenicity tobacco products but generally been performed using partitioned exposures (e.g. total particulate matter [TPM], gas vapor phase [GVP]) rather than whole smoke (WS). VITROCELL®VC10® exposure system offers multiple platforms for air liquid interface (ALI), or agar (AAI) case to mimic vivo-like conditions assessing toxicological impact fresh WS vitro assays. goals this study were 1) qualify demonstrate functionality...
The Vitrocell® VC10® smoke exposure system offers multiple platforms for air liquid interface (ALI) and agar (AAI) that mimic in vivo conditions assessing toxicological impact of whole using vitro assays. aim this study was to investigate compare dosimetry techniques may be employed during combustible cigarette the smoking robot. following were assessed: (1) quartz crystal microbalances (QCMs), (2) aerosol photometers (using area under curve, AUC), (3) fluorescence anhydrous dimethyl...
ABSTRACT The allergy vaccine Pollinex® Quattro Grass, developed for the prevention/relief of allergic symptoms caused by grass pollen in adults and children, contains extracts 12 pollens rye cereal (all chemically modified glutaraldehyde), adsorbed onto l ‐tyrosine with addition immunostimulatory adjuvant monophosphoryl lipid A (MPL®). This paper represents first publication on genetic toxicology data such a vaccine. An Ames test using five strains Salmonella typhimurium at concentrations up...
The assessment of potential cytotoxicity or genotoxicity combustible tobacco products has historically been performed using partitioned exposures (i.e. total particulate matter [TPM], gas vapor phase [GVP]) rather than whole smoke. VITROCELL® VC10® smoke exposure system offers multiple platforms for air liquid interface (ALI) agar (AAI) to mimic in vivo-like conditions assessing the toxicological impact vitro assays (e.g. cytotoxicity, mutagenicity and DNA modifications). aims this study...