- HIV Research and Treatment
- Suicide and Self-Harm Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Receptor Mechanisms and Signaling
- Immune Cell Function and Interaction
- interferon and immune responses
- Jewish and Middle Eastern Studies
- Middle East and Rwanda Conflicts
- Psychosomatic Disorders and Their Treatments
- Nicotinic Acetylcholine Receptors Study
- Child and Adolescent Psychosocial and Emotional Development
- Biblical Studies and Interpretation
Rosalind Franklin University of Medicine and Science
2021-2022
Columbia University
2018-2019
University of St. Thomas - Minnesota
2012
Behavioral measures are increasingly used to assess suicidal thoughts and behaviors.Some measures, such as the Suicide Stroop task, have yielded mixed findings in literature.An understudied feature of these behavioral has been their psychometric properties, which may affect probability detecting significant effects reproducibility.In largest investigation its kind, we tested internal consistency concurrent validity Task, drawing from seven separate studies (N=875 participants, 64% female,...
HIV infection of astrocytes leads to restricted gene expression and replication but abundant early genes Tat, Nef Rev. A great deal neuroHIV research has so far been focused on Tat protein, its effects astrocytes, roles in neuroHIV. In the current study, we aimed determine their function. Using transfection or VSVG-pseudotyped viruses, showed that down-modulated glial fibrillary acidic protein (GFAP) expression. We then also led decreased GFAP mRNA The transcriptional regulation was further...
Abstract HIV-associated neurocognitive disorders (HAND) in the era of combination antiretroviral therapy are primarily manifested as impaired behaviours, glial activation/neuroinflammation and compromised neuronal integrity, for which there no effective treatments currently available. In current study, we used doxycycline-inducible astrocyte-specific HIV Tat transgenic mice (iTat), a surrogate HAND model, determined effects PNU-125096, positive allosteric modulator α7 nicotinic acetylcholine...
Ancient texts present the reader with an insurmountable challenge—namely, distance. Concerning book of Lamentations, which was a response to destruction Temple in 586 bce, readers are too removed from raw experience grief that gave rise lament first place. One way overcome this obstacle—though imperfectly—is juxtapose Lamentations more recent and better documented horror. This article offers analysis women children juxtaposed experiences Holocaust. The goal study is not replace Holocaust;...