A5042882484- Colorectal and Anal Carcinomas
- Hidradenitis Suppurativa and Treatments
- Head and Neck Surgical Oncology
- Pituitary Gland Disorders and Treatments
- Cytomegalovirus and herpesvirus research
- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Mosquito-borne diseases and control
- Spinal Fractures and Fixation Techniques
- Seaweed-derived Bioactive Compounds
- Intracranial Aneurysms: Treatment and Complications
- Nerve injury and regeneration
- Corneal Surgery and Treatments
- Herpesvirus Infections and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- CNS Lymphoma Diagnosis and Treatment
- Peripheral Nerve Disorders
- CRISPR and Genetic Engineering
- Orthopedic Surgery and Rehabilitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Autoimmune Bullous Skin Diseases
- Glioma Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Erythropoietin and Anemia Treatment
- Bone Tumor Diagnosis and Treatments
Mackay Memorial Hospital
2016-2025
Mackay Medical College
2015-2025
Creative Commons
2023
National Taiwan University
1999-2012
Oxidative stress is identified as a major inducer of retinal pigment epithelium (RPE) cell dysregulation and associated with age-related macular degeneration (AMD). The protection RPE disorders plays an essential role in the pathological progress diseases. pharmacological functions fucoxanthin, characteristic carotenoid, including anti-inflammatory antioxidant properties, may ameliorate outstanding bioactivity against premature senescence cellular dysfunction. This study demonstrates that...
Background: Tonsillectomy is a common surgery in the US, with possible postoperative complications.While small studies indicate depressive symptoms may occur, large-scale evidence lacking on tonsillectomy-depression link.Methods: We conducted retrospective cohort study using TriNetX US collaborative network, offering de-identified electronic health data from 59 healthcare organizations (HCOs) United States.In this study, people being diagnosed of chronic tonsillitis between January 2005 and...
Peripheral nerve injury (PNI) commonly leads to motor or sensory dysfunction, with grafts being the standard treatment for neurorrhaphy. Despite advancements in biomaterials nerve-tissue engineering, rate of regeneration remains slow. Therefore, this study aims improve further understanding impact syndecan-3 (SDC3)-modified small intestine submucosa (SIS) on reconstruction by employing two advanced approaches: cation recruitment and local growth factor delivery. Immunofluorescence staining...
Fucoxanthin is a carotenoid with many pharmaceutical properties that found in brown seaweed. However, the effects of fucoxanthin on corneal innervation and intense eye pain have not been extensively examined. To clarify protective roles underlying mechanisms ocular lesions, we investigated beneficial by which ameliorates ultraviolet B (UVB)-induced denervation trigeminal pain. Treatment enhanced expression nuclear factor erythroid 2-related 2 cornea. Inhibition typical epithelial exfoliation...
Ultraviolet B (UVB) irradiation is the most common cause of radiation damage to eyeball and a risk factor for human corneal damage. We determined protective effect fucoxanthin, which carotenoid found in edible seaweed, on ocular tissues against oxidative UVB-induced injury. The experimental rats were intravenously injected with fucoxanthin at doses 0.5, 5 mg/kg body weight/day or vehicle before UVB irradiation. Lissamine green surface staining showed that caused serious surface, including...
Inflammation and oxidative stress are closely related processes in the pathogenesis of various ocular diseases. Uveitis is a disorder uvea tissues that causes extreme pain, decreases visual acuity, can eventually lead to blindness. The pharmacological functions fucoxanthin, isolated from brown algae, induce variety therapeutic effects such as reduction repression inflammation reactions. However, specific anti-inflammatory fucoxanthin on pathogen-associated molecular pattern (PAMP)...
Introduction While an association between hidradenitis suppurativa (HS) and inflammatory arthritis has been reported in clinical studies, the potential link HS gout remains uncertain. As share common immunological pathways, we conducted a retrospective cohort study to determine whether patients are at increased risk of developing future. Methods This multicenter obtained information through US collaborative network, subset TriNetX research network. Patients diagnosed with January 01, 2005,...
The F1 protein of Yersinia pestis is a major antigen for triggering immunity against plague in animals. It was currently used as model to establish technology platform highly efficient antibody induction. antigen-loaded liposomes (F1-liposomes) were prepared using the patent formulation platform. F1-liposome further tested vitro phosphate-buffered saline (PBS) solvent and its content determined by bicinchoninic acid (BCA) assay. F1-liposomes administered into immunocompetent Balb/c mice...
Meningioma is one of the most common primary brain neoplasms with poor outcomes. The present study was aimed to determine clinical and surgical characteristics intracranial meningiomas associated tumor recurrence complications. A total 138 patients undergoing resection between Jan 2003 Dec 2014 were included followed for period at least 12 months. demographic possibly assessed, including age, gender, symptoms, pathology data, parameters, preoperative postoperative Karnofsky Performance Scale...
This study developed an optical module for laser headlamps with a tunable light field. Laser have high and low beam lighting functions that are applied by changing the numbers of unit headlamps. For regulatory validation, we validated project in accordance Regulation No. 112 Economic Commission Europe (ECE) to determine whether results meet requirements or not. The proposed design increased distance 2.14 times decreased size mechanism 45% relative values LED High were provided same sources.
Cytomegalovirus (CMV) infections are still a global health problem, because the latent viruses persist in humans and cause recurring diseases. Currently, there no therapies for CMV active limited by side effects other problems. It is impossible to eradicate animals. HCMV (human CMV) specific human diseases; however, it difficult study due its host specificity long life cycle. Fortunately, MCMV (murine provides an excellent animal model. Here, three pairs of transcription activator-like...