A5013387868- Neonatal Respiratory Health Research
- Ultrasound in Clinical Applications
- Congenital Diaphragmatic Hernia Studies
- Neonatal and fetal brain pathology
- Neonatal and Maternal Infections
- Respiratory viral infections research
- COVID-19 Impact on Reproduction
- Pneumonia and Respiratory Infections
- Pleural and Pulmonary Diseases
- Pregnancy and Medication Impact
- Sepsis Diagnosis and Treatment
- Parvovirus B19 Infection Studies
- Central Venous Catheters and Hemodialysis
- Vaccine Coverage and Hesitancy
- Infant Development and Preterm Care
- Infectious Encephalopathies and Encephalitis
- Myasthenia Gravis and Thymoma
- Thyroid and Parathyroid Surgery
- Dermatological and COVID-19 studies
- COVID-19 and healthcare impacts
- Inflammasome and immune disorders
- Autoimmune and Inflammatory Disorders Research
- Blood Coagulation and Thrombosis Mechanisms
- Kawasaki Disease and Coronary Complications
- Ectopic Pregnancy Diagnosis and Management
Bambino Gesù Children's Hospital
2021-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2022
Università Cattolica del Sacro Cuore
2017
Subcutaneous fat necrosis (SCFN) in newborns is an uncommon and self-limiting non-infectious panniculitis. It can occur the first weeks of life full-term with hypoxic-ischemic encephalopathy who underwent therapeutic hypothermia. Hypercalcemia may develop has been implicated as cause several complications nephrocalcinosis. previously reported to appear only after resolution skin lesions. Herein, we report how hypercalcemia be evident already at diagnosis subcutaneous hypothermia associated...
Abstract TBX4 gene, located on human chromosome 17q23.2, encodes for T-Box Transcription Factor 4, a transcription factor that belongs to the T-box gene family and it is involved in regulation of some embryonic developmental processes, with significant impact respiratory skeletal illnesses. Herein, we present case female neonate persistent pulmonary hypertension (PH) who underwent extracorporeal membrane oxygenation (ECMO) first day life then resulted have novel variant identified by...
Abstract Objectives The diagnostic accuracy of presepsin (P-SEP) in the newborn is still under evaluation. Methods In a multicenter study, we studied P-SEP as marker late-onset sepsis (LOS) critical newborns with underlying disorders, to define most accurate cut-off distinguish infected from uninfected patients. Results Sixty-nine/351 without infections at admission developed LOS. median value T0 (admission) was 518.0 ng/L (IQR 313.0–789.0), significant differences related diseases (p=0.52)....
Abstract Objective To propose an early lung ultrasound (LUS) score for the prediction of need respiratory assistance in newborns gestational age (GA) ≥ 33 weeks presenting distress. Study Design and Setting Multicenter, prospective observational study third‐level neonatal intensive care units. Patient Selection Infants with GA + 0 distress within 3 h life. Methods Three LUS each patient were collected: life (T0), at 4–6 (T1), resolution symptoms (T2). The primary aim was to assess validity...
(1) Background: Infections in pregnancy can lead to miscarriage, premature birth, infections newborns, and developmental disabilities babies. Infected infants, symptomatic at have long-term sequelae, asymptomatic babies are also increased risk of developing sensorineural outcomes. Targeted therapy the pregnant mother reduce fetal neonatal harm. (2) Aim study: To explore association between symptoms time onset sequelae infected children born from mothers who contracted an infection during...
Bronchiolitis severity can be assessed using different clinical scores. Some of the most used are Wang Severity Score (WBSS), Kristjansson Respiratory (KRS), and Global (GRSS), calculated on vital parameters conditions.To assess which three scores better predicts need for respiratory support length hospital stay in neonates infants younger than months, admitted to neonatal units bronchiolitis.Neonates months from October 2021 March 2022 were included this retrospective study. The all...
Introduction: The use of a lung ultrasound (LUS) score has been described in the early phases neonatal respiratory distress syndrome; however, there is still no data regarding application LUS to neonates with congenital diaphragmatic hernia (CDH). objective this observational cross-sectional study was explore, for first time, postnatal changes patterns CDH, creation new specific CDH-LUS score. Methods: We included all consecutive prenatal diagnosis CDH admitted our Neonatal Intensive Care...
Abstract Aim To compare Presepsin (presepsin) levels in plasma and urine of uninfected newborn infants with perinatal asphyxia those controls. Methods In this prospective study, we enrolled 25 full‐term 19 We measured presepsin whole blood or urine. neonates asphyxia, compared at four time points. Results urinary matched each other any point. At admission, the median value was similar both groups ( p = 0.74), while were higher hypoxic 0.05). Perinatal seemed to increase serum CRP...
(1) Background: Massive social efforts to prevent the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic have affected epidemiological features infections. (2) Methods: The study aims describe trend hospitalizations for bronchiolitis among newborns and infants up three months life in Rome (Italy), pre-COVID-19 era during pandemic. (3) Results: We observed a marked decrease number neonates with after national lockdowns 2020 first 2021 similar caused by syncytial...
Intracranial hemorrhage may represent a complication of the perinatal period that affects neonatal morbidity and mortality. Very poor data exist about possible association between mutations type IV collagen a1 chain ( COL4A1 ) gene development intracranial hemorrhage, only sporadic reports focus on intracerebral bleedings already developing in utero or infants with such mutation. This study presents case series term neonates affected by no apparent risk factors for this condition, who were...
In the literature, there are no studies about transfusion threshold for neonates with hypoxic-ischemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). order to facilitate accurate interpretation of coagulation results in these neonates, we aimed generate specific reference intervals this population.
Background The lung ultrasound (LUS) score can be a useful tool to predict the need for respiratory support and length of hospital stay in infants with bronchiolitis. Objective To compare features neonates up three months age bronchiolitis determine whether LUS scores (range 0–36) differ coinfections or not. Methods Neonates younger than admitted neonatal units from October 2022 March 2023, who underwent evaluation on admission, were included this retrospective study. Results We 60 patients...
Abstract Background Particulate contamination due to infusion therapy (administration of parenteral nutrition and medications) carries a potential health risk for infants in neonatal intensive care units (NICUs). This particulate consists metals, drug crystals, glass fragments, or cotton fibers can be generated by packaging, incomplete reconstitution, chemical incompatibilities. In-line filters have been shown remove micro-organisms, endotoxin, air, particles critically ill adults older...